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Cited by 256

The DOI matches its Crossref record; 203 of the 203 references it cites were found in a registry or an index.

Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease

Open access
Attanasio, John, Wherry, E. John·2016·Immunity

Abstract

Costimulatory and inhibitory receptors play a key role in regulating immune responses to infections. Recent translation of knowledge about inhibitory receptors such as CTLA-4 and PD-1 into the cancer clinic highlights the opportunities to manipulate these pathways to treat human disease. Studies in infectious disease have provided key insights into the specific roles of these pathways and the effects of their manipulation. Here, recent studies are discussed that have addressed how major inhibitory and costimulatory pathways play a role in regulating immune responses during acute and chronic infections. Mechanistic insights from studies of infectious disease provide opportunities to further expand our toolkit to treat cancer and chronic infections in the clinic.

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Metadata

Authors
Attanasio, J., & Wherry, E. J.
Venue
Immunity
Publisher
Elsevier BV
Published
2016-05
Volume
44
Issue
5
Pages
1052-1068
ISSN
1074-7613 (ISSN-L)
OpenAlex
W2403151371
Cited by
256
References
203
FWCI
14.47
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease. https://app.cochat.ai/papers/10.1016/j.immuni.2016.04.022
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Attanasio, J., & Wherry, E. J. (2016). Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease. Immunity. https://doi.org/10.1016/j.immuni.2016.04.022

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.