Essential oils from Eugenia spp.: In vitro antiproliferative potential with inhibitory action of metalloproteinases
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β-Caryophyllene has demonstrated antimicrobial, anticarcinogenic, anti-inflammatory, antioxidant, anxiolytic-like, and local anesthetic effects and anticancer properties, including against prostate, breast, pancreatic, skin, leukemia, lymphatic, and cervical cancer.
“It has demonstrated antimicrobial, anticarcinogenic, anti-inflammatory, antioxidant, anxiolytic-like, and local anesthetic effects and anticancer properties, including against prostate, breast, pancreatic, skin, leukemia, lymphatic, and cervical cancer [11,14,21,37,38,39,40,41].”
From Clove essential oil (Syzygium aromaticum L. Myrtaceae): Extraction, chemical composition, food applications, and essential bioactivity for human health (2021) · cites this paper as [38]
β-Caryophyllene can act as a chemosensitizer, improving the effectiveness of drugs against tumor cells.
“β-Caryophyllene can act as a chemosensitizer, improving the effectiveness of drugs against tumor cells [37,38,40].”
From Clove essential oil (Syzygium aromaticum L. Myrtaceae): Extraction, chemical composition, food applications, and essential bioactivity for human health (2021) · cites this paper as [38]
β-Caryophyllene is effective against Anopheles subpictus (LC50 = 41.66 μg/mL), Aedes albopictus (LC50 = 44.77 μg/mL), and Culex tritaeniorhynchus (LC50 = 48.17 μg/mL).
“It is also effective against Anopheles subpictus (LC50 = 41.66 μg/mL), Aedes albopictus (LC50 = 44.77 μg/mL), and Culex tritaeniorhynchus (LC50 = 48.17 μg/mL).”
From Clove essential oil (Syzygium aromaticum L. Myrtaceae): Extraction, chemical composition, food applications, and essential bioactivity for human health (2021) · cites this paper as [38]
β-Caryophyllene decreases cell growth and proliferation in colon cancer, interferes with the stages of tumor development, and reduces the activity of extracellular matrix metalloproteinases.
“These studies suggest that β-caryophyllene decreases cell growth and proliferation in colon cancer, interfering with the stages of tumor development and reducing the activity of extracellular matrix metalloproteinases.”
From Clove essential oil (Syzygium aromaticum L. Myrtaceae): Extraction, chemical composition, food applications, and essential bioactivity for human health (2021) · cites this paper as [38]
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References 68 · Cited by 17
- Authors
- Aranha, E. S. P., de Azevedo, S. G., dos Reis, G. G., Silva Lima, E., Machado, M. B., & de Vasconcellos, M. C.
- Affiliations
- Universidade Federal do Amazonas (BR)
- Venue
- Industrial Crops and Products
- Publisher
- Elsevier BV
- Published
- 2019-12
- Volume
- 141
- Pages
- 111736
- ISSN
- 0926-6690 (ISSN-L)
- OpenAlex
- W2972038239
- Cited by
- 17
- References
- 68
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 1 · 2023: 4 · 2022: 3 · 2021: 3 · 2020: 1
- FWCI
- 1.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Industrial Crops and Products (publishedVersion)
- Funders
- oordination for the Improvement of Higher Education Personnel
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Insect Pest Control Strategies
- Keywords
- essential oils, antiproliferative activity, cytotoxicity, metalloproteinases, MMP-2, MMP-9, caryophyllene oxide, α-copaene, MCF-7 cells, DNA damage, cell migration, anticancer activity
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