Mangiferin antagonizes TNF-α-mediated inflammatory reaction and protects against dermatitis in a mice model

Zhao, Yunpeng; Wang, Wenhan; Wu, Xihai; Ma, Xiaoqian; Qu, Ruize; Chen, Xiaomin; Liu, Chenghao; Liu, Yaoge; Wang, Xiaokai; Yan, Pengcheng; Zhang, Hao; Pan, Jingrui; Li, Weiwei

doi:10.1016/j.intimp.2017.02.014

Mangiferin antagonizes TNF-α-mediated inflammatory reaction and protects against dermatitis in a mice model

This study aimed to investigate whether mangiferin played a protective role in a well-established dermatitis mouse model and tumor necrosis factor alpha (TNF-α)-induced RAW264.7 macrophages. Contact dermatitis is an inflammatory skin disease in the clinic, while its underlying mechanism still rem…