Cited by 37Child Welfare and AdoptionChild Abuse and TraumaChild and Adolescent Psychosocial and Emotional Development

Course of Disinhibited Social Engagement Disorder From Early Childhood to Early Adolescence

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Guyon-Harris, Katherine L., Humphreys, Kathryn L., Fox, Nathan A., Nelson, Charles A., Zeanah, Charles H.·2018·Journal of the American Academy of Child & Adolescent Psychiatry

Abstract

Objective Disinhibited social engagement disorder (DSED) is poorly understood beyond early childhood. The course of DSED signs in a sample of children who experienced severe, early deprivation from early childhood to early adolescence was examined using variable-centered (linear mixed modeling) and person-centered (growth mixture modeling) approaches.Method The study included 124 children with a history of institutional care from a randomized controlled trial of foster care as an alternative to institutional care and 69 community comparison children matched by age and sex. DSED signs were assessed at baseline (mean age 22 months), 30, 42, and 54 months of age, and 8 and 12 years of age using a validated caregiver report of disturbed attachment behavior.Results Variable-centered analyses based on intent-to-treat groups indicated that signs of DSED decreased sharply for children randomized to foster care and decreased slightly but remained high for children randomized to care as usual. Person-centered analyses showed 4 profiles (i.e., elevated, persistent modest, early decreasing, and minimal). Elevated and persistent modest courses were associated with greater placement disruptions (F 3,99 = 4.29, p = .007, partial eta-squared [η 2] = 0.12), older age at placement into foster care (F 3,56 = 3.41, p < .05, partial η 2 = 0.16), and more time in institutional care (F 3,115 = 11.91, p < .001, partial η 2 = 0.24) compared with decreasing and minimal courses.Conclusion Early and sustained placement into families after deprivation is associated with minimal or decreasing signs of DSED across development. Shortening the amount of time children spend in institutions and preserving placements could help decrease signs of DSED into early adolescence in previously institutionalized children.

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Crossref · 10.1016/j.jaac.2018.02.009

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  • Among children who received the intervention, individual differences in the timing of placement into foster care between 6 and 33 months and in placement stability were associated with outcomes in several areas.

    “Consistent with previous analyses of discrete timepoints and domains (15-17, 19, 29), we found that, among children who received the intervention, individual differences in timing of placement into foster care between the ages of 6-33 months and the stability of this placement were associated with outcomes in several areas.”

    From A Comprehensive Multilevel Analysis of the Bucharest Early Intervention Project: Causal Effects on Recovery From Early Severe Deprivation (2023) · cites this paper as [16]

    The Results section reports that, among children assigned to foster care, age at placement was associated with DSED course; the Discussion also links placement disruptions to more DSED signs. These passages support the claim for DSED, but do not establish outcomes in several areas or specify a placement-age range of 6–33 months. Page numbers are not available in our copy. (LLM, conf=0.85)

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  • Prior publications have documented the effects of the foster care intervention across development extensively.

    “The effects of the foster care intervention across development have been documented extensively (e.g., [14][15][16][17][18][19]).”

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References 43 · Cited by 37

Research works printed but not linked: 1

  1. [27]Grimm KJ Ram N Estabrook R Growth Modeling: Structural Equation and Multilevel Modeling Approaches New York, NY Guilford Press 2016 https://www.guilford.com/books/Growth-Modeling/Grimm-Ram-Estabrook/9781462526062/summary. Accessed July 20, 2017

Authors
Guyon-Harris, K. L., Humphreys, K. L., Fox, N. A., Nelson, C. A., & Zeanah, C. H.
Affiliations
  • Tulane University (US)
  • University of Maryland, College Park (US)
  • Boston Children's Hospital (US)
Corresponding author
Zeanah, Charles H.
Venue
Journal of the American Academy of Child & Adolescent Psychiatry
Publisher
Elsevier BV
Published
2018-05
Volume
57
Issue
5
Pages
329-335.e2
ISSN
0890-8567 (ISSN-L)
OpenAlex
W2792519310
Cited by
37
References
43
Citations by year
2026: 1 · 2025: 2 · 2024: 2 · 2023: 5 · 2022: 5 · 2021: 9 · 2020: 4 · 2019: 4 · 2018: 5
FWCI
10.96
Type
journal article
Language
en
Open access
Locations
  • Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Mental Health (F32MH107129, R01MH091363)
Topics
  • Social Sciences › Safety Research › Child Welfare and Adoption
  • Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords
disinhibited social engagement disorder, foster care, attachment disruption, developmental course, placement disruption, age at placement, caregiver reports, early deprivation, early adolescence
MeSH terms
Child, Child, Institutionalized, Child, Preschool, Female, Foster Home Care, Humans, Infant, Longitudinal Studies, Male, Surveys and Questionnaires, Social Behavior Disorders, Randomized Controlled Trials as Topic, Caregivers, Reactive Attachment Disorder

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