The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics
Open accessAbstract
Background Merkel cell carcinoma (MCC) incidence rates are rising and strongly age‐associated, relevant for an aging population. Objective Determine MCC incidence in the United States and project incident cases through the year 2025. Methods Registry data were obtained from the SEER‐18 Database, containing 6600 MCC cases. Age‐ and sex‐adjusted projections were generated using US census data. Results During 2000‐2013, the number of reported solid cancer cases increased 15%, melanoma cases increased 57%, and MCC cases increased 95%. In 2013, the MCC incidence rate was 0.7 cases/100,000 person‐years in the United States, corresponding to 2488 cases/year. MCC incidence increased exponentially with age, from 0.1 to 1.0 to 9.8 (per 100,000 person‐years) among age groups 40‐44 years, 60‐64 years, and ≥85 years, respectively. Due to aging of the Baby Boomer generation, US MCC incident cases are predicted to climb to 2835 cases/year in 2020 and 3284 cases/year in 2025. Limitations We assumed that the age‐adjusted incidence rate would stabilize, and thus, the number of incident cases we projected might be an underestimate. Conclusion An aging population is driving brisk increases in the number of new MCC cases in the United States. This growing impact combined with the rapidly evolving therapeutic landscape warrants expanded awareness of MCC diagnosis and management.
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Colorectal cancer statistics, 2017
Siegel, R. L., Miller, K. D., Fedewa, S. A., Ahnen, D. J., Meester, R. G. S., Barzi, A., & Jemal, A. (2017) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21395 · Cited by 3,806
Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma
Feng, H., Shuda, M., Chang, Y., & Moore, P. S. (2008) · Science · doi:10.1126/science.1152586 · Cited by 3,208
Trabecular Carcinoma of the Skin
Toker, C. (1972) · Archives of Dermatology · doi:10.1001/archderm.1972.01620040075020 · Cited by 1,350
PD-1 Blockade with pembrolizumab in advanced Merkel-cell carcinoma
Nghiem, P. T., Bhatia, S., Lipson, E. J., Kudchadkar, R. R., Miller, N. J., Annamalai, L., Berry, S., Chartash, E. K., Daud, A., Fling, S. P., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1603702 · Cited by 1,258
Self-citationKaufman, H. L., Russell, J., Hamid, O., Bhatia, S., Terheyden, P., D'Angelo, S. P., Shih, K. C., Lebbé, C., Linette, G. P., Milella, M., et al. (2016) · The Lancet Oncology · doi:10.1016/s1470-2045(16)30364-3 · Cited by 1,236
Self-citationClinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features
Heath, M., Jaimes, N., Lemos, B., Mostaghimi, A., Wang, L. C., Peñas, P. F., & Nghiem, P. (2008) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2007.11.020 · Cited by 934
Self-citationUnderstanding immunosenescence to improve responses to vaccines
Goronzy, J. J., & Weyand, C. M. (2013) · Nature Immunology · doi:10.1038/ni.2588 · Cited by 827
Seroepidemiology of Human Polyomaviruses
Kean, J. M., Rao, S., Wang, M., & Garcea, R. L. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000363 · Cited by 731
Epidemiology of primary Merkel cell carcinoma in the United States
Agelli, M., & Clegg, L. X. (2003) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(03)02108-x · Cited by 568
Vital signs: melanoma incidence and mortality trends and projections - United States, 1982-2030.
Guy, G. P., Thomas, C. C., Thompson, T., Watson, M., Massetti, G. M., & Richardson, L. C. (2015) · PubMed Central · Cited by 567
Cited by
Nghiem, P., Bhatia, S., Lipson, E. J., Sharfman, W. H., Kudchadkar, R. R., Brohl, A. S., Friedlander, P. A., Daud, A., Kluger, H. M., Reddy, S. A., et al. (2019) · Journal of Clinical Oncology · doi:10.1200/jco.18.01896 · Cited by 396
Self-citationMerkel Cell Carcinoma, Version 1.2018, NCCN Clinical Practice Guidelines in Oncology
Bichakjian, C. K., Olencki, T., Aasi, S. Z., Alam, M., Andersen, J. S., Blitzblau, R., Bowen, G. M., Contreras, C. M., Daniels, G. A., Decker, R., et al. (2018) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2018.0055 · Cited by 319
Self-citationMerkel cell carcinoma: an updated review focused on bone and bone marrow metastases
Scotti, B., Broseghini, E., Ricci, C., Corti, B., Viola, C., Misciali, C., Baraldi, C., Vaccari, S., Lambertini, M., Venturi, F., et al. (2025) · Cancers · doi:10.3390/cancers17132253 · Cited by 9
Metadata
- Authors
- Paulson, K. G., Park, S. Y., Vandeven, N. A., Lachance, K., Thomas, H., Chapuis, A. G., Harms, K. L., Thompson, J. A., Bhatia, S., Stang, A., & Nghiem, P.
- Venue
- Journal of the American Academy of Dermatology
- Publisher
- Elsevier BV
- Published
- 2018-03
- Volume
- 78
- Issue
- 3
- Pages
- 457-463.e2
- ISSN
- 0190-9622 (ISSN-L)
- OpenAlex
- W2766831098
- Cited by
- 528
- References
- 34
- FWCI
- 15.73
- Type
- journal article
- Language
- en
- Open access
- green
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- Paulson, K. G., Park, S. Y., Vandeven, N. A., Lachance, K., Thomas, H., Chapuis, A. G., Harms, K. L., Thompson, J. A., Bhatia, S., Stang, A., & Nghiem, P. (2018). Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics. Journal of the American Academy of Dermatology. https://doi.org/10.1016/j.jaad.2017.10.028
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