The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease

Brunner, Patrick M.; He, Helen; Pavel, Ana B.; Czarnowicki, Tali; Lefferdink, Rachel; Erickson, Taylor; Canter, Talia; Puar, Neha; Rangel, Stephanie M.; Malik, Kunal; Estrada, Yeriel; Krueger, James G.; Guttman-Yassky, Emma; Paller, Amy S.

doi:10.1016/j.jaad.2019.04.036

The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease

BACKGROUND Despite increasing evidence that adults with long-standing atopic dermatitis (AD) have systemic inflammation, little is known about systemic inflammation in recent-onset early pediatric AD. OBJECTIVE To analyze blood inflammatory proteins of early pediatric AD. METHODS Using high-throu…