The Problem With Composite End Points in Cardiovascular Studies

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Items 201–300 of 348

1. Participation in disease management programs and major adverse cardiac events in patients after acute myocardial infarction: a longitudinal study based on registry data
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2. Return to work following adverse cardiovascular events in adults with congenital heart disease
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3. Huffman and colleagues' response to Abramson and colleagues' article on statins in low risk people
   Mark D. Huffman, Fiona C. Taylor, Shah B J Ebrahim · 2014 · BMJ
4. Association between coronary monosodium urate deposits at DECT and high-risk coronary plaque phenotypes and other features in gout patients
   Pietro Giacomo Lacaita, Andrea Sabine Klauser, Julia Held, David Haschka, Gerlig Widmann, Gudrun Maria Feuchtner · 2025 · European Radiology Experimental
5. Decreased risk of cardiovascular disease in dermatology patients taking niacinamide: A TriNetX cohort study
   Yousef Salem, Maryam Liaqat, Nadeen Gonna, Dina Hani Zamil, Ferris Abu-Ghosh, Anwar Merie, Dimitri C. Cassimatis, Ida F. Orengo · 2025 · Journal of the American Academy of Dermatology
6. Infarctus du myocarde, accident vasculaire cérébral et psoriasis : une revue systématique des études observationnelles
   Tulio L Correa, Matheus Augusto Coelho Quitete, Luísa Tavares de Azevedo, Isadora Assis Caiado Fraga, Luísa C. Teixeira · 2022 · Annales de Cardiologie et d Angéiologie
7. Days alive and out of hospital at 30 days and outcomes of off-pump coronary artery bypass grafting
   Ah Ran Oh, Seung Hwa Lee, Jungchan Park, Jeong Jin Min, Jong‐Hwan Lee, Seung Yeon Yoo, Ji‐Hye Kwon, Dan-Cheong Choi, Wooksung Kim, Hyun Sung Cho · 2023 · Scientific Reports
8. Effects of Non-Face-to-Face Chronic Care Management on Service Utilization and Outcomes Among US Medicare Beneficiaries with Diabetes
   Dongzhe Hong, Charles Stoecker, Yixue Shao, Elizabeth Nauman, Vivian Andrew Fonseca, Gang Hu, Alessandra N. Bazzano, Edmond Kato Kabagambe, Lizheng Shi · 2024 · Journal of General Internal Medicine
9. Prognostic impact of left ventricular ejection fraction in patients with electrical storm
   Julian Müller, Michael Behnes, Dominik Ellguth, Tobias Schupp, Gabriel Taton, Linda Reiser, Thomas Reichelt, Armin Bollow, Seung Hyun Kim, Christian Barth et al. · 2019 · Journal of Interventional Cardiac Electrophysiology
10. Effects of a Secondary Prevention Combination Therapy with beta-Blocker and Statin on Major Adverse Cardiovascular Events in Acute Coronary Syndrome Patients
    Ling Zhu, Qianwei Cui, Ying Liu, Zhongwei Liu, Yong Zhang, Fuqiang Liu, Junkui Wang · 2020 · Medical Science Monitor
11. Comparing different types of statins for secondary prevention of cardio-cerebrovascular disease from a national cohort study
    Joungyoun Kim, Hyeong-Seop Kim, Yun-Jong Bae, Hyeong-Chul Lee, Jae‐woo Lee, Hee‐Taik Kang · 2021 · PLoS ONE
12. Heart failure clinical trials: how do we define success?
    Boback Ziaeian, Gregg C. Fonarow · 2013 · Nature Reviews Cardiology
13. Copeptin, myeloperoxidase and pro-adrenomedullin for acute coronary syndrome in patients with chronic kidney disease
    Jen Heng Pek, Stephanie Man Chung Fook-Chong, Jason Chon Jun Choo, Carol Hui Chen Tan, Ziwei Lin, Choong Meng Chan, Chin Pin Yeo, Swee Han Lim · 2019 · Proceedings of Singapore Healthcare
14. Renal Denervation After USA FDA Approval: An Update from an Interventional Cardiologist’s Perspective
    Jiandong Zhang, Peter Matthew Belford, George A. Stouffer · 2025 · Journal of Clinical Medicine
15. Machine Learning Using Clinical and Cardiac MRI Features to Predict Long-term Outcomes in Acute STEMI
    Wei‐Hui Xie, RuoYang Shi, Jinyi Xiang, Binghua Chen, Dong‐Aolei An, Yan Zhou, Lei Zhao, Jun Pu, Lian‐Ming Wu · 2026 · Radiology
16. Cost Change of Elective Percutaneous Coronary Artery Intervention for Chronic Coronary Syndrome in Japan From 2010 to 2019
    Masahiko Fujihara, Tomofumi Tsukizawa, Yuko Yazu, Sachiko Tsujikawa, Yoshiaki Yokoi, Daisuke Uesima · 2023 · Circulation Journal
17. Development of a novel point-of-care device to monitor arterial thrombosis
    Christopher A. Bresette, Viviana Clavería, David N. Ku · 2025 · Lab on a Chip
18. A flexible multi‐domain test with adaptive weights and its application to clinical trials
    Yang Zhao, Qifeng Yu, Stephen L. Lake · 2019 · Pharmaceutical Statistics
19. Early postoperative acute myocardial infarction in kidney transplant recipients: A nested case‐control study
    Maya Deeb, Nikita Gupta, Christopher B. Overgaard, Yanhong Li, Olusegun Famure, Sang Joseph Kim · 2021 · Clinical Transplantation
20. CHA2DS2-VASc predicts readmission, outcomes and resource utilization in patients undergoing coronary artery bypass grafting: A 7-year National Readmission Database study
    Syed Emir Irfan Wafa, Hiroyuki Sawatari, Raheel Ahmed, Saurabh Ajit Deshpande, HASSAN KHAN, Rui Andre Providencia, Deepak Padmanabhan, Virend Kristen Somers, Kamleshun Ramphul, Wael Ibrahim Awad et al. · 2024 · International Journal of Cardiology
21. The need for further guidance on the handling of multiple outcomes in randomized controlled trials: a scoping review of the methodological literature
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22. Chinese primary knee osteoarthritis progression cohort (CPKOPC) to evaluate the progression of knee osteoarthritis in the Beijing population: a prospective cohort study protocol
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23. Composite End Points
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24. Predicted burden could replace predicted risk in preventive strategies for cardiovascular disease
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25. Disease overarching mechanisms that explain and predict outcome of patients with high cardiovascular risk: rationale and design of the Berlin Long-term Observation of Vascular Events (BeLOVE) study
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26. Cardiac Events
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27. Coronary Event
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28. Performance of the EDACS-ADP incorporating high-sensitivity troponin assay: Do components of major adverse cardiac events matter?
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29. Development of a Novel Risk-Prediction Tool for Emergency Department Patients with Symptoms of Coronary Artery Disease: A Research Study Protocol
    Andrew D. McRae, A Macci, Jessalyn K. Holodinsky, Tolulope T. Sajobi, James E. Andruchow, Bjug Borgundvaag, Steven C. Brooks, Ivy Cheng, Saswata Deb, Patrick T. Fok et al. · 2025 · CJC Open
30. Exploring the trimethylamine pathway in advanced chronic liver disease
    Jil T. Bürki, Jonas Schropp, Peter J. Neyer, Christian Steuer, Jaime Bosch, Annalisa Berzigotti, Susana Gomes Rodrigues · 2025 · npj gut and liver.
31. Statistical methods for composite analysis of recurrent and terminal events in clinical trials
    Yiyuan Huang, Douglas Earl Schaubel, Min Zhang · 2025 · Lifetime Data Analysis
32. The influence of serum uric acid on risks of major adverse cardiovascular events in patients with acute coronary syndrome
    Cheng‐Hung Chiang, Mei-Chi Wang, En‐Shao Liu, Tse-Hsuan Yang, Haw-Ting Tai, Jeng-Fung Hung, Feng Yu Kuo · 2025 · BMC Cardiovascular Disorders
33. The Combined Prognostic Value of the Systemic Immune-Inflammation Index and LDL-C in Patients with AMI Undergoing PPCI
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34. Recurrent myocardial infarction and adherence to secondary prevention strategies among adults with coronary artery disease in rural Aluva, South India: a nested case–control study
    Neeraj Vinod Mohandas, Vijayakumar Krishnapillai, Neethu Sara George, Avani Dinesh, Vinod Mohandas · 2025 · BMC Public Health
35. Adult isolated coronary artery ectasia: clinical features and long-term outcomes
    Yihan Weng, Jiquan Xiao, Xiang He, Yusi Huang, Wenzhi Hu, Renshang Xu, Huimin M. Yu · 2026 · Frontiers in Cardiovascular Medicine
36. Optimizing identification of major adverse limb and cardiovascular events among adults with peripheral artery disease in administrative data
    Hasan Nassereldine, Samantha Syme, Neha Dinesh Shetty, Stuthi Iyer, Daniel E. Hall, Katherine Moll Reitz · 2026 · Journal of Vascular Surgery
37. Complication and Endpoint Heterogeneity in Vascular Intervention Research: Lessons from Neurovascular Practice
    Pablo Albiña-Palmarola, Ali Khanafer, Hans H. Henkes · 2026 · Journal of Vascular Diseases
38. Metabolic status modifies the predictive value of the C-reactive protein–triglyceride–glucose Index–waist-to-height ratio for major adverse cardiovascular and cerebrovascular events: a prospective cohort study from the China Health and Retirement Longitudinal Study (CHARLS)
    Xuanzhe Li, Yitong Meng, Lishuang Zhang, Tingmin Li, Gen Yan · 2026 · Cardiovascular Diabetology
39. Chronic kidney disease impairs prognosis in electrical storm
    Kathrin Weidner, Michael Behnes, Tobias Schupp, Jorge Hoppner, Uzair Ansari, Julian Mueller, Simon Lindner, Martin M. Borggrefe, Seung Hyun Kim, Aydin Huseyinov et al. · 2021 · Journal of Interventional Cardiac Electrophysiology
40. Dual therapy with an oral non-vitamin K antagonist and a P2Y12 inhibitor vs triple therapy with aspirin, a P2Y12 inhibitor and a vitamin K antagonist for the treatment of diabetes mellitus patients with co-existing atrial fibrillation following percutaneous coronary intervention
    Qiang Wang, Keping Yang · 2021 · Medicine
41. The Protocol-Personalized Perioperative Hemodynamic Management as Part of the ERAS Protocol in Abdominal Surgeries
    K. Е. Kharlamov, Mikhail Ya. Yadgarov, Valery V. Likhvantsev · 2021 · Messenger of Anesthesiology and Resuscitation
42. Performance of Cardiovascular Risk Prediction Models in Korean Patients With New‐Onset Rheumatoid Arthritis: National Cohort Study
    Jae Hyun Kim, Gaeun Lee, Jinseub Hwang, JW Kim, Jin‐Won Kwon, Yun‐Kyoung Song · 2023 · Journal of the American Heart Association
43. Akut koroner sendromda perkütan koroner girişim yapılan hastalarda kontrast nefropati prevalansı
    Muhammed Karadeniz, Hüseyin Kandemir, Taner Sarak, Çağlar Alp · 2018 · Journal of Health Sciences and Medicine
44. Temporal trends in diagnosis, treatment, and outcome for non-ST-segment elevation acute coronary syndrome in three regions of China, 2008–2015
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45. Coronary Artery Disease
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46. Prognostic impact of recurrences in patients with electrical storm
    Julian Müller, Michael Behnes, Dominik Ellguth, Tobias Schupp, Kambis Mashayekhi, Martin M. Borggrefe, İbrahim Akın · 2019 · Scandinavian Cardiovascular Journal
47. Risk Assessment of Development of the Major Adverse Cardiac Events in Patients with Chronic Heart Failure with a Preserved and Intermediate Ejection Fraction in the Presence of a Bendopnea Symptom
    A. D. Gasanova, Д. О. Драгунов, Anna V. Sokolova, G. P. Arutyunov · 2020 · Kardiologiia
48. The prognostic value of CHA2DS2‐VASc and modified‐CHADS2 scores for cardiovascular events in diabetics and non‐diabetics haemodialysis patients
    Theodoros Tourountzis, Γεώργιος Λιούλιος, Evdoxia Ginikopoulou, Fotini Stasini, Zoi Skarlatou, Stamatia Stai, Michalis Christodoulou, Eleni Moysidou, Maria J. Stangou · 2023 · Nephrology
49. Risk Factors Associated with Contrast-Induced Nephropathy after Primary Percutaneous Coronary Intervention
    2023 · Current Science International
50. Comment on: Combination therapy with long-acting bronchodilators and the risk of major adverse cardiovascular events in patients with COPD: a systematic review and meta-analysis
    Pere Almagro, Pablo Martínez‐Camblor · 2022 · European Respiratory Journal
51. Correlation between serum laminin level and prognosis of acute heart failure
    Xiaoyun Yan, Jiaqi Ye, Haixiao Chen, Ying Jiang, Ling Xie, Ying Wen Zhang, Wenhui Qiang, Hongli Cai, Koulong Zheng, Qing Zhang · 2023 · Clinical Cardiology
52. Nomogram to Predict Outcomes After Staged Revascularization in ST-Segment Elevation Myocardial Infarction and Multivessel Coronary Artery Disease
    Huaigen Wang, Aiqun Ma, Tingzhong Wang · 2024 · International Journal of General Medicine
53. Methodological Pitfalls in Aggregating Nonstandardized Composite Outcomes in Meta-analyses: Mixing Apples and Oranges
    Pedro Robson Costa Passos, Valbert Oliveira Costa Filho, Mariana Macambira Noronha, Rodrigo Vieira Motta · 2025 · Diabetes Care
54. Therapies for alcohol use disorder in alcohol-associated hepatitis clinical trials: Integrated trial design with a composite clinical outcome as the primary endpoint
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55. Assessment of Clinical Pharmacist-Initiated Optimisation of Pharmacotherapy in Patients with Acute Coronary Syndrome
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56. Circ_0049271: A Novel Circular RNA Biomarker for Diagnosis and Prognostic Assessment in Acute Myocardial Infarction
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57. Plant-based diet indices in relation to novel cardiovascular risk factors, major adverse cardiovascular events, and novel anthropometric indices in patients with type 2 diabetes
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58. SURPASS ‐ CVOT and the Emerging Biology of Cardiometabolic Benefit
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59. A Modified Treatment Failure Classification System with Complete and Exhaustive Accounting of Any Adverse Events Related to the Previous Percutaneous Coronary Intervention
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60. Comparative Effectiveness Research
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61. Perioperative Antiplatelet Drugs with Coronary Stents and Dancing with Surgeons: Can We Ever Agree About Bleeding Versus Ischemic Risk?
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62. Drug-eluting stents versus bare-metal stents for stable ischaemic heart disease
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63. EFFECTS OF WORKING ENVIRONMENT ON ISCHEMIC HEART DISEASE BURDEN PROFILE IN YOUNG EGYPTIAN MALES
    Hany Negm, Moatez Fayez, El Mahdy N, Youssef A · 2013 · Egyptian Journal of Occupational Medicine
64. Identify Unsuitable Patients with Left Main Coronary Artery Disease in Intermediate SYNTAX Scores Treated by Percutaneous Coronary Intervention
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65. Comparison of outcomes in emergency department patients with suspected cardiac chest pain: two-centre prospective observational study in Southern China
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66. Prognostic Impact of Atrial Fibrillation in Electrical Storm
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67. Association between left ventricular ejection fraction and mortality after Bentall procedure
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68. Applying Exercise Capacity and Physical Activity as Single vs Composite Endpoints for Trials of Cardiac Rehabilitation Interventions: Rationale, Use-case, and a Blueprint Method for Sample Size Calculation
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69. Increased risk of major adverse cardiovascular events in young and middle-aged adults with obesity receiving Chinese herbal medicine: A nationwide cohort study
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74. Association of Apolipoprotein E Gene Polymorphism with Lipid Profile in Patients with Acute Coronary Syndrome in Han Chinese: A Critical Review
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