Cited by 205Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and ManagementHealth Promotion and Cardiovascular Prevention

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Primary Prevention of Cardiovascular Disease in Diabetes Mellitus

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Newman, Jonathan D., Schwartzbard, Arthur Z., Weintraub, Howard S., Goldberg, Ira J., Berger, Jeffrey S.·2017·Journal of the American College of Cardiology

DOI 10.1016/j.jacc.2017.07.001PMC PMC5656394

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Abstract

Type 2 diabetes mellitus (T2D) is a major risk factor for cardiovascular disease (CVD), the most common cause of death in T2D. Yet, <50% of U.S. adults with T2D meet recommended guidelines for CVD prevention. The burden of T2D is increasing: by 2050, approximately 1 in 3 U.S. individuals may have T2D, and patients with T2D will comprise an increasingly large proportion of the CVD population. The authors believe it is imperative that we expand the use of therapies proven to reduce CVD risk in patients with T2D. The authors summarize evidence and guidelines for lifestyle (exercise, nutrition, and weight management) and CVD risk factor (blood pressure, cholesterol and blood lipids, glycemic control, and the use of aspirin) management for the prevention of CVD among patients with T2D. The authors believe appropriate lifestyle and CVD risk factor management has the potential to significantly reduce the burden of CVD among patients with T2D.

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Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N Engl J Med 2013;368:1279-90.
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Additional file 4 of Effects of inappropriate cause-of-death certification on mortality from cardiovascular disease and diabetes mellitus in Tonga
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Additional file 1 of Effects of inappropriate cause-of-death certification on mortality from cardiovascular disease and diabetes mellitus in Tonga
Figueroa, C. A., Linhart, C., Dearie, C., Fusimalohi, L., Kupu, S., Morrell, S. L., & Taylor, R. J. (2023) · Figshare · doi:10.6084/m9.figshare.24715474
Additional file 5 of Effects of inappropriate cause-of-death certification on mortality from cardiovascular disease and diabetes mellitus in Tonga
Figueroa, C. A., Linhart, C., Dearie, C., Fusimalohi, L., Kupu, S., Morrell, S. L., & Taylor, R. J. (2024) · Figshare · doi:10.6084/m9.figshare.26648106
Additional file 1 of Interaction between smoking and diabetes in relation to subsequent risk of cardiovascular events
Yang, Y., 彭年春, Chen, G., Wan, Q., Yan, L., Wang, G., Qin, Y., Luo, Z., Tang, X., Huo, Y., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19029174
Additional file 3 of Effects of inappropriate cause-of-death certification on mortality from cardiovascular disease and diabetes mellitus in Tonga
Figueroa, C. A., Linhart, C., Dearie, C., Fusimalohi, L., Kupu, S., Morrell, S. L., & Taylor, R. J. (2024) · Figshare · doi:10.6084/m9.figshare.26648100
Additional file 1 of Association of circulating PCSK9 concentration with cardiovascular metabolic markers and outcomes in stable coronary artery disease patients with or without diabetes: a prospective, observational cohort study
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Additional file 6 of Effects of inappropriate cause-of-death certification on mortality from cardiovascular disease and diabetes mellitus in Tonga
Figueroa, C. A., Linhart, C., Dearie, C., Fusimalohi, L., Kupu, S., Morrell, S. L., & Taylor, R. J. (2024) · Figshare · doi:10.6084/m9.figshare.26648109
Additional file 1 of Association of caffeine intake with all-cause and cardiovascular mortality in diabetes and prediabetes
Yao, H., Li, L., Wang, X., & Wang, Z. (2024) · Figshare · doi:10.6084/m9.figshare.26384552
Additional file 1 of Integrated investigation and discovery of therapeutic targets for 3-hydroxybakuchiol against diabetes based on molecular docking studies and cell experiments
Liu, M., Wang, X., Yang, J., & Qin, D. (2023) · Figshare · doi:10.6084/m9.figshare.24669828
Additional file 7 of Effects of inappropriate cause-of-death certification on mortality from cardiovascular disease and diabetes mellitus in Tonga
Figueroa, C. A., Linhart, C., Dearie, C., Fusimalohi, L., Kupu, S., Morrell, S. L., & Taylor, R. J. (2024) · Figshare · doi:10.6084/m9.figshare.26648112
Additional file 2 of Effects of inappropriate cause-of-death certification on mortality from cardiovascular disease and diabetes mellitus in Tonga
Figueroa, C. A., Linhart, C., Dearie, C., Fusimalohi, L., Kupu, S., Morrell, S. L., & Taylor, R. J. (2024) · Figshare · doi:10.6084/m9.figshare.24715520
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Asad, M. B., Shafiq, S. S., Naeem, S., Farooq, A. R., Ahmed, M., Tahir, M., Ansari, M. H., Razzak, M. J., & Waqas, S. A. (2026) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-026-01895-7
Pneumonia as a predictor of diabetes mellitus and coronary heart disease: a national cohort study
Jansåker, F., Li, X., Sundquist, K., & Stenberg, H. (2026) · Pneumonia · doi:10.1186/s41479-026-00199-x
Cardiovascular risk factors in adults with type 2 diabetes mellitus: Retrospective study
Ríos, E. D. S. G., Yupari-Azabache, I. L., Otiniano, N. M., & Gómez-Goicochea, N. I. (2026) · F1000Research · doi:10.12688/f1000research.181792.1
Cardiovascular Risk Awareness Among Adults in the Northern Border Region of Saudi Arabia: A Cross-Sectional Study with Emphasis on Hypertension and Type 2 Diabetes
Alanazi, R. A., Alenezi, A. S., Aldhafeeri, R. J., Alanazi, R. A. M., Alshammari, A. H., Alanazi, G. B., Alenzi, M. K., Alenezi, A. A. A., Alsel, B. T. A., Mersal, F. A., et al. (2026) · Diseases · doi:10.3390/diseases14070233

Authors: Newman, J. D., Schwartzbard, A. Z., Weintraub, H. S., Goldberg, I. J., & Berger, J. S.
Affiliations: NYU Langone Health (US)
Corresponding author: Newman, Jonathan D.
ORCID: Newman, Jonathan D.
Weintraub, Howard S.
Goldberg, Ira J.
Berger, Jeffrey S.
Venue: Journal of the American College of Cardiology
Publisher: Elsevier BV
Published: 2017-08
Volume: 70
Issue: 7
Pages: 883-893
ISSN: 0735-1097 (ISSN-L)
DOI: 10.1016/j.jacc.2017.07.001
PMC: PMC5656394
OpenAlex: W2744536672
Cited by: 205
References: 89
Citations by year: 2026: 10 · 2025: 13 · 2024: 28 · 2023: 22 · 2022: 57 · 2021: 18 · 2020: 21 · 2019: 14 · 2018: 20 · 2017: 2
FWCI: 2.27
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 379 d)
Locations: Journal of the American College of Cardiology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: American Heart Association (15MCPRP24480132)
Amgen
AstraZeneca
Sanofi
Gilead Sciences
Amarin Corporation
National Institutes of Health (HL114978)
National Heart, Lung, and Blood Institute (P01HL092969, K23HL125991, HL-114978, R01HL114978)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
Keywords: type 2 diabetes, cardiovascular disease prevention, primary prevention, lifestyle modification, physical activity, nutrition, weight management, blood pressure control, glycemic control, aspirin therapy, cardiovascular risk factors
MeSH terms: Cardiovascular Diseases, Diabetes Mellitus, Type 2, Humans, Morbidity, Primary Prevention, Risk Factors, Global Health

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Primary Prevention of Cardiovascular Disease in Diabetes Mellitus

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