The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Dual Antiplatelet Therapy Duration Based on Ischemic and Bleeding Risks After Coronary Stenting
Open accessAbstract
BACKGROUND Complex percutaneous coronary intervention (PCI) is associated with higher ischemic risk, which can be mitigated by long-term dual antiplatelet therapy (DAPT). However, concomitant high bleeding risk (HBR) may be present, making it unclear whether short- or long-term DAPT should be prioritized. OBJECTIVES This study investigated the effects of ischemic (by PCI complexity) and bleeding (by PRECISE-DAPT [PREdicting bleeding Complications in patients undergoing stent Implantation and SubsequEnt Dual AntiPlatelet Therapy] score) risks on clinical outcomes and on the impact of DAPT duration after coronary stenting. METHODS Complex PCI was defined as ≥3 stents implanted and/or ≥3 lesions treated, bifurcation stenting and/or stent length >60 mm, and/or chronic total occlusion revascularization. Ischemic and bleeding outcomes in high (≥25) or non-high (<25) PRECISE-DAPT strata were evaluated based on randomly allocated duration of DAPT. RESULTS Among 14,963 patients from 8 randomized trials, 3,118 underwent complex PCI and experienced a higher rate of ischemic, but not bleeding, events. Long-term DAPT in non-HBR patients reduced ischemic events in both complex (absolute risk difference: -3.86%; 95% confidence interval: -7.71 to +0.06) and noncomplex PCI strata (absolute risk difference: -1.14%; 95% confidence interval: -2.26 to -0.02), but not among HBR patients, regardless of complex PCI features. The bleeding risk according to the Thrombolysis In Myocardial Infarction scale was increased by long-term DAPT only in HBR patients, regardless of PCI complexity. CONCLUSIONS Patients who underwent complex PCI had a higher risk of ischemic events, but benefitted from long-term DAPT only if HBR features were not present. These data suggested that when concordant, bleeding, more than ischemic risk, should inform decision-making on the duration of DAPT.
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Cites
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
Wallentin, L., Becker, R. C., Budaj, A., Cannon, C. P., Emanuelsson, H., Held, C., Horrow, J., Husted, S., James, S., Katus, H., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0904327 · Cited by 7,117
Self-citationClinical End Points in Coronary Stent Trials: A Case for Standardized Definitions
Cutlip, D. E., Windecker, S., Mehran, R., Boam, A., Cohen, D. J., van Es, G.-A., Gabriel Steg, P., Morel, M.-A., Mauri, L., Vranckx, P., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.685313 · Cited by 5,497
Self-citationValgimigli, M., Bueno, H., Byrne, R. A., Collet, J.-P., Costa, F., Jeppsson, A., Jüni, P., Kastrati, A., Kolh, P., Mauri, L., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehx419 · Cited by 2,987
Self-citationChesebro, J. H., Knatterud, G., Roberts, R., Borer, J., Cohen, L. S., Dalen, J., Dodge, H. T., Francis, C. K., Hillis, D., & Ludbrook, P. (1987) · Circulation · doi:10.1161/01.cir.76.1.142 · Cited by 2,244
Twelve or 30 Months of Dual Antiplatelet Therapy after Drug-Eluting Stents
Mauri, L., Kereiakes, D. J., Yeh, R. W., Driscoll-Shempp, P., Cutlip, D. E., Steg, P. G., Normand, S.-L. T., Braunwald, E., Wiviott, S. D., Cohen, D. J., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1409312 · Cited by 1,928
Self-citationLevine, G. N., Bates, E. R., Bittl, J. A., Brindis, R. G., Fihn, S. D., Fleisher, L. A., Granger, C. B., Lange, R. A., Mack, M. J., Mauri, L., et al. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.03.513 · Cited by 1,641
Statistics with Confidence: Confidence Intervals and Statistical Guidelines.
Jolliffe, F. R., Gardner, M. J., & Altman, D. G. (1990) · Journal of the Royal Statistical Society. Series A (Statistics in Society) · doi:10.2307/2982808 · Cited by 1,319
Costa, F., van Klaveren, D., James, S., Heg, D., Räber, L., Feres, F., Pilgrim, T., Hong, M.-K., Kim, H.-S., Colombo, A., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)30397-5 · Cited by 1,184
Self-citationEverolimus-Eluting versus Paclitaxel-Eluting Stents in Coronary Artery Disease
Stone, G. W., Rizvi, A., Newman, W., Mastali, K., Wang, J. C., Caputo, R., Doostzadeh, J., Cao, S., Simonton, C. A., Sudhir, K., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0910496 · Cited by 902
Self-citationPolymer-free Drug-Coated Coronary Stents in Patients at High Bleeding Risk
Urban, P., Meredith, I. T., Abizaid, A., Pocock, S. J., Carrié, D., Naber, C., Lipiecki, J., Richardt, G., Iñiguez, A., Brunel, P., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1503943 · Cited by 818
Metadata
- Authors
- Costa, F., Van Klaveren, D., Feres, F., James, S., Räber, L., Pilgrim, T., Hong, M.-K., Kim, H.-S., Colombo, A., Steg, P. G., Bhatt, D. L., Stone, G. W., Windecker, S., Steyerberg, E. W., & Valgimigli, M.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2019-02
- Volume
- 73
- Issue
- 7
- Pages
- 741-754
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2911481227
- Cited by
- 325
- References
- 37
- FWCI
- 31.30
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Costa, F., Van Klaveren, D., Feres, F., James, S., Räber, L., Pilgrim, T., Hong, M.-K., Kim, H.-S., Colombo, A., Steg, P. G., Bhatt, D. L., Stone, G. W., Windecker, S., Steyerberg, E. W., & Valgimigli, M. (2019). Dual Antiplatelet Therapy Duration Based on Ischemic and Bleeding Risks After Coronary Stenting. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2018.11.048
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