The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Surgery Does Not Improve Survival in Patients With Isolated Severe Tricuspid Regurgitation
Open accessAbstract
Background: Patients with isolated tricuspid regurgitation (TR) in the absence of left-sided valvular dysfunction are historically managed nonoperatively. Objectives: To assess the impact of surgery for isolated TR, we compared survival for isolated severe TR patients who underwent surgery to those who did not. Methods: A longitudinal echocardiography database was used to perform a retrospective analysis on 3,276 adult patients with isolated severe TR from November 2001-March 2016. All-cause mortality for patients who underwent surgery versus those who did not was analyzed in the entire cohort and a propensity-matched sample. To assess the possibility of immortal time bias, the analysis was performed considering time from diagnosis to surgery as a time-dependent covariate. Results: Of 3,276 patients with isolated severe TR, 171 (5%) underwent tricuspid valve surgery, including 143 (84%) repairs and 28 (16%) replacements. The remaining 3,105 (95%) patients were medically managed. When considering surgery as a time-dependent covariate in a propensity matched sample, there was no difference in overall survival between patients who received medical versus surgical therapy (HR 1.34 [0.78–2.30], p=0.288). In the subgroup that underwent surgery, there was no difference in survival between tricuspid repair versus replacement (HR 1.53 [0.74–3.17], p=0.254). Conclusion: In patients with isolated severe TR, surgery is not associated with improved long-term survival compared to medical management alone after accounting for immortal time bias.
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Cites
Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation
Zoghbi, W. A., Adams, D., Bonow, R. O., Enriquez-Sarano, M., Foster, E., Grayburn, P. A., Hahn, R. T., Han, Y., Hung, J., Lang, R. M., et al. (2017) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2017.01.007 · Cited by 3,556
Immortal Time Bias in Pharmacoepidemiology
Suissa, S. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwm324 · Cited by 1,708
Impact of tricuspid regurgitation on long-term survival
Nath, J., Foster, E., & Heidenreich, P. A. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.09.036 · Cited by 1,677
Haddad, F., Hunt, S. A., Rosenthal, D. N., & Murphy, D. J. (2008) · Circulation · doi:10.1161/circulationaha.107.653576 · Cited by 1,523
Haddad, F., Doyle, R., Murphy, D. J., & Hunt, S. A. (2008) · Circulation · doi:10.1161/circulationaha.107.653584 · Cited by 1,304
National Trends and Outcomes in Isolated Tricuspid Valve Surgery
Zack, C. J., Fender, E. A., Chandrashekar, P., Reddy, Y. N. V., Bennett, C. E., Stulak, J. M., Miller, V. M., & Nishimura, R. A. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.10.039 · Cited by 648
Clinical Outcome of Isolated Tricuspid Regurgitation
Topilsky, Y., Nkomo, V. T., Vatury, O., Michelena, H. I., Letourneau, T., Suri, R. M., Pislaru, S., Park, S., Mahoney, D. W., Biner, S., et al. (2014) · JACC: Cardiovascular Imaging · doi:10.1016/j.jcmg.2014.07.018 · Cited by 620
The need for a new tricuspid regurgitation grading scheme
Hahn, R. T., & Zamorano, J. L. (2017) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jex139 · Cited by 574
Landmark Analysis at the 25-Year Landmark Point
Dafni, U. (2011) · Circulation: Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.110.957951 · Cited by 569
Gammie, J. S., Sheng, S., Griffith, B. P., Peterson, E. D., Rankin, J. S., O'Brien, S. M., & Brown, J. M. (2009) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2009.01.064 · Cited by 513
Cited by
2021 ESC/EACTS Guidelines for the management of valvular heart disease
Vahanian, A., Beyersdorf, F., Praz, F., Milojevic, M., Baldus, S., Bauersachs, J., Capodanno, D., Conradi, L., De Bonis, M., De Paulis, R., et al. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehab395 · Cited by 5,685
Otto, C. M., Nishimura, R. A., Bonow, R. O., Carabello, B. A., Erwin, J. P., Gentile, F., Jneid, H., Krieger, E. V., Mack, M., McLeod, C., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000923 · Cited by 3,686
Self-citationOtto, C. M., Nishimura, R. A., Bonow, R. O., Carabello, B. A., Erwin, J. P., Gentile, F., Jneid, H., Krieger, E. V., Mack, M., McLeod, C., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000932 · Cited by 2,449
Self-citation2021 ESC/EACTS Guidelines for the management of valvular heart disease
Beyersdorf, F., Vahanian, A., Milojevic, M., Praz, F., Baldus, S., Bauersachs, J., Capodanno, D., Conradi, L., De Bonis, M., De Paulis, R., et al. (2021) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezab389 · Cited by 622
JCS/JSCS/JATS/JSVS 2020 Guidelines on the Management of Valvular Heart Disease
Izumi, C., Eishi, K., Ashihara, K., Arita, T., Otsuji, Y., Kunihara, T., Komiya, T., Shibata, T., Seo, Y., Daimon, M., et al. (2020) · Circulation Journal · doi:10.1253/circj.cj-20-0135 · Cited by 367
Metadata
- Authors
- Axtell, A. L., Bhambhani, V., Moonsamy, P., Healy, E. W., Picard, M. H., Sundt, T. M., & Wasfy, J. H.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2019-08
- Volume
- 74
- Issue
- 6
- Pages
- 715-725
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2942949171
- Cited by
- 312
- References
- 25
- FWCI
- 25.76
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Axtell, A. L., Bhambhani, V., Moonsamy, P., Healy, E. W., Picard, M. H., Sundt, T. M., & Wasfy, J. H. (2019). Surgery Does Not Improve Survival in Patients With Isolated Severe Tricuspid Regurgitation. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2019.04.028
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