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Diagnosis and Evaluation of Hypertrophic Cardiomyopathy

Maron, Barry J., Desai, Milind Y., Nishimura, Rick A., Spirito, Paolo, Rakowski, Harry, Towbin, Jeffrey A., Rowin, Ethan J., Maron, Martin S., Sherrid, Mark V.·2022·Journal of the American College of Cardiology

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Crossref · 10.1016/j.jacc.2021.12.002

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(A and B) Absence of systolic anterior motion and out fl ow obstruction; and (C and D) out fl ow gradient under resting conditions. (C) Stress (exercise) induced obstruction to left ventricular (LV) out fl ow due to anterior mitral lea fl et contact with ventricular septum (VS) (double arrows) , (D) producing a continuous-wave Doppler estimate of a 100-mm Hg gradient (5-m/s jet). (E to G) Transesophageal images showing (E) systolic anterior motion and septal contact (arrow) typically associated with (F) a secondary posteriorly directed mitral regurgitation jet (double arrows) . (G) In another patient, an anterior and centrally directed jet from intrinsic mitral valve pathology requiring operative repair (triple arrows) . Reproduced with permission from Rowin et al. 4 Ao ¼ aorta; LA ¼ left atrium.
(A and B) Absence of systolic anterior motion and out fl ow obstruction; and (C and D) out fl ow gradient under resting conditions. (C) Stress (exercise) induced obstruction to left ventricular (LV) out fl ow due to anterior mitral lea fl et contact with ventricular septum (VS) (double arrows) , (D) producing a continuous-wave Doppler estimate of a 100-mm Hg gradient (5-m/s jet). (E to G) Transesophageal images showing (E) systolic anterior motion and septal contact (arrow) typically associated with (F) a secondary posteriorly directed mitral regurgitation jet (double arrows) . (G) In another patient, an anterior and centrally directed jet from intrinsic mitral valve pathology requiring operative repair (triple arrows) . Reproduced with permission from Rowin et al. 4 Ao ¼ aorta; LA ¼ left atrium.CC-BY-NC-ND · From the PDF
(A) Changes to left ventricular (LV) out fl ow tract gradient from basal (rest) to immediately after physiologic (exercise) provocation in 200 hypertrophic cardiomyopathy patients. 72 Each exercised patient is depicted by a line connecting the 2 gradient measurements. Ø ¼ group means. Reproduced with permission from Maron et al. 72 (B) Relation of gradients at rest or with exercise provocation (while NYHA functional class I/II) to subsequent progressive heart failure (New York Heart Association [NYHA] functional class III/IV).
(A) Changes to left ventricular (LV) out fl ow tract gradient from basal (rest) to immediately after physiologic (exercise) provocation in 200 hypertrophic cardiomyopathy patients. 72 Each exercised patient is depicted by a line connecting the 2 gradient measurements. Ø ¼ group means. Reproduced with permission from Maron et al. 72 (B) Relation of gradients at rest or with exercise provocation (while NYHA functional class I/II) to subsequent progressive heart failure (New York Heart Association [NYHA] functional class III/IV).CC-BY-NC-ND · From the PDF
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ACC ¼ American College of Cardiology; AHA ¼ American Heart Association; ESC ¼ European Society of Cardiology; HCM ¼ hypertrophic cardiomyopathy; SAM ¼ systolic anterior motion.
ACC ¼ American College of Cardiology; AHA ¼ American Heart Association; ESC ¼ European Society of Cardiology; HCM ¼ hypertrophic cardiomyopathy; SAM ¼ systolic anterior motion.CC-BY-NC-ND · From the PDF

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Research works printed but not linked: 75

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Metadata

Authors
Maron, B. J., Desai, M. Y., Nishimura, R. A., Spirito, P., Rakowski, H., Towbin, J. A., Rowin, E. J., Maron, M. S., & Sherrid, M. V.
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
2022-02
Volume
79
Issue
4
Pages
372-389
ISSN
0735-1097
Cited by
637
References
2
Language
en
Funders
  • Pfizer
  • Takeda Pharmaceuticals U.S.A.

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