The intersect of genetics, environment, and microbiota in asthma—perspectives and challenges

Tang, Howard H.F.; Teo, Shu Mei; Sly, Peter D.; Holt, Patrick G.; Inouye, Michael

doi:10.1016/j.jaci.2020.08.026

The intersect of genetics, environment, and microbiota in asthma—perspectives and challenges

In asthma, a significant portion of the interaction between genetics and environment occurs through microbiota. The proposed mechanisms behind this interaction are complex and at times contradictory. This review covers recent developments in our understanding of this interaction: the "microbial h…