The Major Cat Allergen, Fel d 1, Is a Viable Target for CRISPR Gene Editing.
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Using CRISPR-Cas9, exons CH1 and CH2 were deleted in CRFK cells with an efficiency of 55%.
“Using CRISPR-Cas9, exons CH1 and CH2 were deleted in CRFK cells with an efficiency of 55% [119,120].”
From Advance in Managing Indoor Cat Allergen Proteins: Molecular Insights, Detection, and Control (2025) · cites this paper as [120]
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Cited by 2
- Authors
- Brackett, N., Pomes, A., & Chapman, M.
- Affiliations
- Indoor Biotechnologies (United States) (US)
- Venue
- Journal of Allergy and Clinical Immunology
- Publisher
- Elsevier BV
- Published
- 2021-02
- Volume
- 147
- Issue
- 2
- Pages
- AB175
- ISSN
- 0091-6749 (ISSN-L)
- OpenAlex
- W3128688767
- Cited by
- 2
- References
- 0
- Citations by year
- 2026: 1 · 2022: 1
- FWCI
- 0.08
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Allergy and Clinical Immunology (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › CRISPR and Genetic Engineering
- Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Animal Genetics and Reproduction
- Keywords
- Fel d 1, cat allergen, CRISPR/Cas9 genome editing, Felis domesticus, IgE sensitization, off-target editing, cat allergy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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