Disrupted sleep and risk of depression in later life: A prospective cohort study with extended follow up and a systematic review and meta-analysis

BACKGROUND Sleep difficulties increase the risk of current and future depression, but it is unclear if this relationship is causal. METHODS Prospective cohort study of a community sample of men aged 70-89 years followed for up to 17 years. Initial assessments occurred between 2001 and 2004. Parti…