Acne: The role of medical nutrition therapy
Abstract
Acne is a common disease in Westernized nations, particularly among adolescents and young adults. Acne has substantial effects on quality of life, making treatment essential. Medical nutrition therapy as a potential treatment for acne is not new, although the literature examining diet and acne during the past 100 years is mixed. During the late 1800s and early 1900s, diet was commonly used as an adjunct treatment for acne. During the 1960s, however, the diet-acne connection fell out of favor. In recent years, dermatologists and registered dietitians have revisited the idea and become increasingly interested in the role of medical nutrition therapy in acne treatment. This article reviews the history and existing literature examining the association between diet and acne. Although the total number of studies conducted within the past 40 years is relatively small, the growing body of epidemiologic and experimental evidence suggests a relationship between diet and acne. Compared with other dietary factors, more research examines dietary glycemic load. The evidence is more convincing for high glycemic load diets, compared with other dietary factors. To date there are no randomized controlled trials investigating the relationship between frequent dairy or milk consumption and acne. Similarly, the number of research studies examining the relationship between dietary fat and/or n-3 fatty acids is sparse and the evidence is less robust. Taken together, several methodologic limitations need to be addressed, and additional research, preferably randomized controlled trials, is warranted before comprehensive evidence-based guidelines can be established. While dermatologists and registered dietitians continue to debate and research the potential relationship between diet and acne, the best dietary approach is to address each acne patient individually, carefully considering the possibility of dietary counseling.
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GLA applied topically as a cream penetrates to the stratum corneum, while taken orally, it reaches the dermis, enhancing its cohesiveness and preventing excessive TEWL.
“GLA applied topically as a cream penetrates to the stratum corneum, while taken orally, it reaches the dermis, enhancing its cohesiveness and preventing excessive TEWL [156,157].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [157]
Essential fatty acids have therapeutic properties (e.g., anti-inflammatory and anti-allergic) and exert protective effects.
“EFAs have therapeutic properties (e.g., anti-inflammatory and anti-allergic) and exert protective effects.”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [157]
Oils rich in essential fatty acids improve skin hydration, have a regenerative effect on the damaged epidermal lipid barrier, and regulate skin metabolism.
“Oils rich in EFAs improve skin hydration, have a regenerative effect on the damaged epidermal lipid barrier, and regulate skin metabolism.”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [157]
Vegetable oils play an important role in the care of dry, sensitive, oily, acne-prone and mature skin.
“Vegetable oils play an important role in the care of dry, sensitive, oily, acne-prone and mature skin [152,157] (Table 2).”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [157]
A deficiency of essential fatty acids can reduce the fluidity of sebum, which leads to the obstruction of the sebaceous glands and the appearance of blackheads and inflammation.
“A deficiency of essential fatty acids can also reduce the fluidity of sebum, which leads to the obstruction of the sebaceous glands and the appearance of blackheads and inflammation [152,157].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [157]
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References 100 · Cited by 82
- Authors
- Burris, J., Rietkerk, W., & Woolf, K.
- Corresponding author
- Burris, Jennifer
- Venue
- Journal of the Academy of Nutrition and Dietetics
- Publisher
- Elsevier BV
- Published
- 2013-03
- Volume
- 113
- Issue
- 3
- Pages
- 416-430
- ISSN
- 2212-2672 (ISSN-L)
- OpenAlex
- W2163403168
- Cited by
- 82
- References
- 100
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 4 · 2023: 8 · 2022: 5 · 2021: 6 · 2020: 4 · 2019: 5 · 2018: 4 · 2017: 9 · 2016: 6 · 2015: 2 · 2014: 13 · 2013: 9
- FWCI
- 1.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the Academy of Nutrition and Dietetics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Keywords
- acne, medical nutrition therapy, diet and acne, glycemic load, dairy consumption, milk consumption, dietary fat, omega-3 fatty acids, nutrition counseling, quality of life
- MeSH terms
- Acne Vulgaris, Adolescent, Dairy Products, Diet, Dietary Carbohydrates, Female, Humans, Male, Quality of Life, Fatty Acids, Omega-3, Treatment Outcome, Glycemic Index, Nutrition Therapy, Young Adult
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