Prevalence of pseudoresistant hypertension due to inaccurate blood pressure measurement
Open accessAbstract
The prevalence of pseudoresistant hypertension (HTN) due to inaccurate BP measurement remains unknown. Triage BP measurements and measurements obtained at the same clinic visit by trained physicians were compared in consecutive adult patients referred for uncontrolled resistant HTN (RHTN). Triage BP measurements were taken by the clinic staff during normal intake procedures. BP measurements were obtained by trained physicians using the BpTRU (VSM Med Tech Ltd. Coquitlam, Canada) device. The prevalence of uncontrolled RHTN and differences in BP measurements were compared. Of 130 patients with uncontrolled RHTN, 33.1% (n = 43) were falsely identified as having uncontrolled RHTN based on triage BP measurements. The median (inter-quartile range) of differences in systolic BP between pseudoresistant and true resistant groups were 23 (17-33) mm Hg and 13 (6-21) mm Hg, respectively (P = .0001). The median (inter-quartile range) of differences in diastolic BP between the two groups were 12 (7-18) mm Hg and 8 (4-11) mm Hg, respectively (P = .001). Triage BP technique overestimated the prevalence of uncontrolled RHTN in approximately 33% of the patients emphasizing the importance of obtaining accurate BP measurements.
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Approximately 50% of patients diagnosed with resistant hypertension have pseudoresistance rather than true resistant hypertension.
“Approximately 50% of patients diagnosed with resistant hypertension have pseudoresistance rather than true resistant hypertension. 104,105,108”
From 2020 International Society of Hypertension Global Hypertension Practice Guidelines (2020) · cites this paper as [104]
The Introduction says pseudoresistance among people with apparent resistant hypertension is estimated to be *as high as* 50%, not that approximately 50% generally have it. The Results report 33.1% attributable to inaccurate blood-pressure measurement in this study's specialty-clinic patients. The claim omits the upper-bound qualifier and presents 50% as a general proportion. (LLM, conf=0.88)
Experimental — accuracy not yet measuredResistant hypertension affects around 10% of hypertensive individuals.
“Resistant hypertension affects around 10% of hypertensive individuals”
From 2020 International Society of Hypertension Global Hypertension Practice Guidelines (2020) · cites this paper as [104]
The Results and Discussion report pseudoresistant hypertension among patients referred for apparent resistant hypertension, not the prevalence of resistant hypertension among all hypertensive individuals. A search for the claimed 10% prevalence found no passage in our copy that addresses it. (LLM, conf=0.76)
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References 41 · Cited by 77
- Authors
- Bhatt, H., Siddiqui, M., Judd, E., Oparil, S., & Calhoun, D.
- Affiliations
- University of Alabama at Birmingham (US)
- Corresponding author
- Bhatt, Hemal
- Venue
- Journal of the American Society of Hypertension
- Publisher
- Elsevier BV
- Published
- 2016-06
- Volume
- 10
- Issue
- 6
- Pages
- 493-499
- ISSN
- 1878-7436 (ISSN-L)
- 1933-1711
- PMC
- PMC4905807
- OpenAlex
- W2334117108
- Cited by
- 77
- References
- 41
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 7 · 2023: 7 · 2022: 10 · 2021: 7 · 2020: 11 · 2019: 10 · 2018: 8 · 2017: 4 · 2016: 4
- FWCI
- 7.15
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Journal of the American Society of Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R01HL113004, T32HL007457)
- National Institute of Diabetes and Digestive and Kidney Diseases (K23DK102660, P30DK079626)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Keywords
- resistant hypertension, prevalence
- MeSH terms
- Adult, Aged, Antihypertensive Agents, Blood Pressure Determination, Coronary Vasospasm, Diagnostic Errors, Female, Humans, Hypertension, Male, Middle Aged, Physicians, Retrospective Studies, Blood Pressure Monitors, Prevalence
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