The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Electron transfer dissociation of peptide anions
Abstract
Ion/ion reactions of multiply deprotonated peptide anions with xenon radical cations result in electron abstraction to generate charge-reduced peptide anions containing a free-radical site. Peptide backbone cleavage then occurs by hydrogen radical abstraction from a backbone amide N to facilitate cleavage of the adjacent C-C bond, thereby producing a- and x-type product ions. Introduction of free-radical sites to multiply charged peptides allows access to new fragmentation pathways that are otherwise too costly (e.g., lowers activation energies). Further, ion/ion chemistry, namely electron transfer reactions, presents a rapid and efficient means of generating odd-electron multiply charged peptides; these reactions can be used for studying gas-phase chemistries and for peptide sequence analysis.
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Citations
Cites
Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry
Syka, J. E. P., Coon, J. J., Schroeder, M. J., Shabanowitz, J., & Hunt, D. F. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402700101 · Cited by 2,370
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High-sensitivity Analytical Approaches for the Structural Characterization of Glycoproteins
Alley, W. R., Mann, B. F., & Novotny, M. V. (2013) · Chemical Reviews · doi:10.1021/cr3003714 · Cited by 310
Metadata
- Authors
- Coon, J. J., Shabanowitz, J., Hunt, D. F., & Syka, J. E. P.
- Venue
- Journal of the American Society for Mass Spectrometry
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-06-01
- Volume
- 16
- Issue
- 6
- Pages
- 880-882
- ISSN
- 1044-0305 (ISSN-L)
- OpenAlex
- W2067708744
- Cited by
- 238
- References
- 1
- FWCI
- 5.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- Coon, J. J., Shabanowitz, J., Hunt, D. F., & Syka, J. E. P. (2005). Electron transfer dissociation of peptide anions. Journal of the American Society for Mass Spectrometry. https://doi.org/10.1016/j.jasms.2005.01.015
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