Cited by 328Clinical practice guidelines implementationMeta-analysis and systematic reviewsHealth Sciences Research and Education

Living systematic reviews: 4. Living guideline recommendations.

Open access
Akl, Elie A., Meerpohl, Joerg J., Elliott, Julian, Kahale, Lara A., Schünemann, Holger J., Agoritsas, Thomas, Hilton, John, Perron, Caroline +128 more·2017·Journal of Clinical Epidemiology

Abstract

While it is important for the evidence supporting practice guidelines to be current, that is often not the case. The advent of living systematic reviews has made the concept of "living guidelines" realistic, with the promise to provide timely, up-to-date and high-quality guidance to target users. We define living guidelines as an optimization of the guideline development process to allow updating individual recommendations as soon as new relevant evidence becomes available. A major implication of that definition is that the unit of update is the individual recommendation and not the whole guideline. We then discuss when living guidelines are appropriate, the workflows required to support them, the collaboration between living systematic reviews and living guideline teams, the thresholds for changing recommendations, and potential approaches to publication and dissemination. The success and sustainability of the concept of living guideline will depend on those of its major pillar, the living systematic review. We conclude that guideline developers should both experiment with and research the process of living guidelines.

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Crossref · 10.1016/j.jclinepi.2017.08.009

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References 27 · Cited by 328

Authors
Akl, E. A., Meerpohl, J. J., Elliott, J., Kahale, L. A., Schünemann, H. J., Agoritsas, T., Hilton, J., Perron, C., Akl, E., Hodder, R., Pestridge, C., Albrecht, L., Horsley, T., Platt, J., Armstrong, R., Nguyen, P. H., Plovnick, R., Arno, A., Ivers, N., Quinn, G., Au, A., Johnston, R., Rada, G., Bagg, M., Jones, A., Ravaud, P., Boden, C., Kahale, L., Richter, B., Boisvert, I., Keshavarz, H., Ryan, R., Brandt, L., Kolakowsky-Hayner, S. A., Salama, D., Brazinova, A., Nagraj, S. K., Salanti, G., Buchbinder, R., Lasserson, T., Santaguida, L., Champion, C., Lawrence, R., Santesso, N., Chandler, J., Les, Z., Schünemann, H. J., Charidimou, A., Leucht, S., Shemilt, I., Chou, R., Low, N., Sherifali, D., Churchill, R., Maas, A., Siemieniuk, R., Cnossen, M. C., MacLehose, H., Simmonds, M., Cossi, M.-J., Macleod, M., Skoetz, N., Counotte, M., Marshall, I., Soares-Weiser, K., Craigie, S., Marshall, R., Srikanth, V., Dahm, P., Martin, N., Sullivan, K., Danilkewich, A., Martínez García, L., Synnot, A., Danko, K., Mavergames, C., Taylor, M., Donoghue, E., Maxwell, L. J., Thayer, K., Dressler, C., McAuley, J., Thomas, J., Egan, C., McDonald, S., Tritton, R., Elliott, J., McKenzie, J., Tsafnat, G., Elliott, S. A., Meerpohl, J., Tugwell, P., Etxeandia, I., Merner, B., Turgeon, A., Featherstone, R., Mondello, S., Turner, T., Foxlee, R., Morley, R., van Valkenhoef, G., Garner, P., Munafo, M., Vandvik, P., Gerrity, M., Munn, Z., Wallace, B., Glasziou, P., Murano, M., Wallace, S. A., Green, S., Newman, K., Watts, C., Grimshaw, J., Nieuwlaat, R., Weeks, L., Gurusamy, K., Nikolakopoulou, A., Weigl, A., Haddaway, N., Noel-Storr, A., Wells, G., Hartling, L., O'Connor, A., Wiercioch, W., Hayden, J., Page, M., Wolfenden, L., Helfand, M., Pahwa, M., Yepes Nuñez, J. J., Higgins, J., Pardo, J. P., Yost, J., Hill, S., & Pearson, L.
Affiliations
Monash University (AU)
Venue
Journal of Clinical Epidemiology
Publisher
Elsevier BV
Published
2017-11
Volume
91
Pages
47-53
ISSN
0895-4356 (ISSN-L)
OpenAlex
W2754128910
Cited by
328
References
27
Citations by year
2026: 25 · 2025: 51 · 2024: 54 · 2023: 52 · 2022: 45 · 2021: 43 · 2020: 32 · 2019: 12 · 2018: 8 · 2017: 5
FWCI
2.53
Type
journal article
Language
en
Open access
Locations
  • Journal of Clinical Epidemiology (publishedVersion)
  • PubMed (publishedVersion)
  • Archive ouverte UNIGE (University of Geneva) (publishedVersion, other-oa)
  • Bond University Research Portal (Bond University) (submittedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
  • UCL Discovery (University College London) (submittedVersion)
  • Griffith Research Online (Griffith University, Queensland, Australia) (submittedVersion)
  • NOVA (University of Newcastle Australia) (submittedVersion)
Funders
  • National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC/L000970/1)
  • Medical Research Council (MR/N015665/1)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
  • Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
  • Health Sciences › Health Professions › General Health Professions › Health Sciences Research and Education
Keywords
living systematic review, living guidelines, guideline recommendations, evidence updating, guideline development
MeSH terms
Decision Making, Humans, Review Literature as Topic, Practice Guidelines as Topic

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