The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
LA Strain for Categorization of LV Diastolic Dysfunction
Open accessAbstract
Objectives This study sought to observe the relationship between left atrial (LA) strain and left ventricular diastolic function and determine whether LA strain could be used to detect diastolic dysfunction (DD) and classify its degree when present. Background The assessment of diastolic function is complex and multiparametric because most conventional parameters do not follow the progression of DD. Strain imaging is an emerging index of LA function, with recent data demonstrating that LA strain is diminished in diastolic heart failure. However, LA strain is not part of the standard assessment of diastolic function. We hypothesized that LA strain decreases with worsening DD in a stepwise fashion and could thus be useful in evaluating DD. Methods We performed a retrospective derivation and validation cohort study to derive and test LA strain thresholds for DD grades (0 to 3) in patients with preserved left ventricular ejection fraction (N = 229). Two-dimensional speckle tracking was used to measure peak LA strain, which was applied as a single parameter to classify DD. American Society of Echocardiography guidelines were used as the reference standard. Results In the derivation cohort (n = 90), peak LA strain was significantly different between DD groups, with gradual decreases seen with worsening DD. Receiver-operating characteristic analysis resulted in 3 distinct LA strain thresholds for categorization of DD grades, with good to excellent diagnostic utility (area under the curve: 0.86 to 0.91). In an independent validation group (n = 139) with a spectrum of diastolic function, 11 patients (8%) had indeterminate DD grades using standard criteria, whereas LA strain was measured in all patients and its cutoffs resulted in diagnostic accuracy up to 95%. Conclusions LA strain measurements are feasible and allow accurate categorization of DD, because unlike the traditional parameters, it changes progressively with severity of DD. LA strain may become a useful tool for diastolic assessment in future clinical practice.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Lang, R. M., Badano, L. P., Mor-Avi, V., Afilalo, J., Armstrong, A., Ernande, L., Flachskampf, F. A., Foster, E., Goldstein, S. A., Kuznetsova, T., et al. (2015) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2014.10.003 · Cited by 12,362
Self-citationNagueh, S. F., Smiseth, O. A., Appleton, C. P., Byrd, B. F., Dokainish, H., Edvardsen, T., Flachskampf, F. A., Gillebert, T. C., Klein, A. L., Lancellotti, P., et al. (2016) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2016.01.011 · Cited by 5,262
Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography
Nagueh, S. F., Appleton, C. P., Gillebert, T. C., Marino, P. N., Oh, J. K., Smiseth, O. A., Waggoner, A. D., Flachskampf, F. A., Pellikka, P. A., & Evangelista, A. (2009) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2008.11.023 · Cited by 4,367
Recommendations for the evaluation of left ventricular diastolic function by echocardiography
Nagueh, S. F., Appleton, C. P., Gillebert, T. C., Marino, P. N., Oh, J. K., Smiseth, O. A., Waggoner, A. D., Flachskampf, F. A., Pellikka, P. A., & Evangelisa, A. (2008) · European Journal of Echocardiography · doi:10.1093/ejechocard/jep007 · Cited by 3,351
Ommen, S. R., Nishimura, R. A., Appleton, C. P., Miller, F. A., Oh, J. K., Redfield, M. M., & Tajik, A. J. (2000) · Circulation · doi:10.1161/01.cir.102.15.1788 · Cited by 2,790
Impaired Systolic Function by Strain Imaging in Heart Failure With Preserved Ejection Fraction
Kraigher-Krainer, E., Shah, A. M., Gupta, D. K., Santos, A., Claggett, B., Pieske, B., Zile, M. R., Voors, A. A., Lefkowitz, M. P., Packer, M., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.09.052 · Cited by 756
Melenovsky, V., Hwang, S.-J., Redfield, M. M., Zakeri, R., Lin, G., & Borlaug, B. A. (2015) · Circulation: Heart Failure · doi:10.1161/circheartfailure.114.001667 · Cited by 530
Left Atrial Function in Diastolic Heart Failure
Kurt, M., Wang, J., Torre-Amione, G., & Nagueh, S. F. (2009) · Circulation: Cardiovascular Imaging · doi:10.1161/circimaging.108.813071 · Cited by 502
Mondillo, S., Cameli, M., Caputo, M. L., Lisi, M., Palmerini, E., Padeletti, M., & Ballo, P. (2011) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2011.04.014 · Cited by 426
Cameli, M., Caputo, M., Mondillo, S., Ballo, P., Palmerini, E., Lisi, M., Marino, E., & Galderisi, M. (2009) · Cardiovascular Ultrasound · doi:10.1186/1476-7120-7-6 · Cited by 389
Cited by
Pieske, B., Tschöpe, C., de Boer, R. A., Fraser, A. G., Anker, S. D., Donal, E., Edelmann, F., Fu, M., Guazzi, M., Lam, C. S. P., et al. (2020) · European Journal of Heart Failure · doi:10.1002/ejhf.1741 · Cited by 394
Redefining Cirrhotic Cardiomyopathy for the Modern Era
Izzy, M., VanWagner, L. B., Lin, G., Altieri, M., Findlay, J. Y., Oh, J. K., Watt, K. D., Lee, S. S., & on behalf of The Cirrhotic Cardiomyopathy Consortium (2020) · Hepatology · doi:10.1002/hep.30875 · Cited by 367
Reddy, Y. N. V., Obokata, M., Egbe, A., Yang, J. H., Pislaru, S., Lin, G., Carter, R., & Borlaug, B. A. (2019) · European Journal of Heart Failure · doi:10.1002/ejhf.1464 · Cited by 316
Left Ventricular Diastolic Function
Nagueh, S. F. (2020) · JACC: Cardiovascular Imaging · doi:10.1016/j.jcmg.2018.10.038 · Cited by 304
Metadata
- Authors
- Singh, A., Addetia, K., Maffessanti, F., Mor-Avi, V., & Lang, R. M.
- Venue
- JACC: Cardiovascular Imaging
- Publisher
- Elsevier BV
- Published
- 2017-07
- Volume
- 10
- Issue
- 7
- Pages
- 735-743
- ISSN
- 1876-7591 (ISSN-L)
- 1936-878X
- OpenAlex
- W2563736117
- Cited by
- 458
- References
- 24
- FWCI
- 19.67
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: LA Strain for Categorization of LV Diastolic Dysfunction. https://app.cochat.ai/papers/10.1016/j.jcmg.2016.08.014
- The paper
- Singh, A., Addetia, K., Maffessanti, F., Mor-Avi, V., & Lang, R. M. (2017). LA Strain for Categorization of LV Diastolic Dysfunction. JACC: Cardiovascular Imaging. https://doi.org/10.1016/j.jcmg.2016.08.014
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
