Simvastatin-loaded PCL/PEG nanofibrous scaffold: A prospective approach for suppression 5-fluorouracil resistance in MKN-45 gastric cancer cells
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Compared to PCL alone, the PCL/PEG/PCL triblock copolymer has been noted to have lower acidity, higher rate of degradation, as well as lower hydrophilicity, thus making it a better alternative to constructing scaffolds for TE applications.
“Compared to PCL alone, the PCL/PEG/PCL triblock copolymer has been noted to have lower acidity, higher rate of degradation, as well as lower hydrophilicity, thus making it a better alternative to constructing scaffolds for TE applications [147].”
From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [147]
The addition of PEG improves the hydrophilicity of PCL, and so cell adherence is also enhanced.
“The addition of PEG improves the hydrophilicity of PCL, and so cell adherence is also enhanced.”
From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [147]
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Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review
Vach Agocsova, S., Culenova, M., Birova, I., Omanikova, L., Moncmanova, B., Danisovic, L., Ziaran, S., Bakos, D., & Alexy, P. (2023) · Materials · doi:10.3390/ma16124267 · Cited by 98 · see citing works
- Authors
- Norouz Dolatabadi, E., Asghariazar, V., Darvish, M., & Nejati-Koshki, K.
- Affiliations
- Ardabil University of Medical Sciences (IR)
- Arak University of Medical Sciences (IR)
- Corresponding author
- Darvish, Maryam
- Venue
- Journal of Drug Delivery Science and Technology
- Publisher
- Elsevier BV
- Published
- 2023-02
- Volume
- 80
- Pages
- 104104
- ISSN
- 1773-2247 (ISSN-L)
- OpenAlex
- W4313253618
- Cited by
- 19
- References
- 0
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 9 · 2023: 3
- FWCI
- 1.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Journal of Drug Delivery Science and Technology (publishedVersion)
- Funders
- Arak University of Medical Sciences
- Topics
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer, Lipids, and Metabolism
- Keywords
- simvastatin, 5-fluorouracil resistance, gastric cancer, MKN45 cells, drug delivery scaffolds, chemoresistance, apoptosis, autophagy, p53, Bax/Bcl-2 ratio, cell migration, combination chemotherapy
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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