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Pharmacovigilance of herbal medicine
Open accessAbstract
Pharmacovigilance is essential for developing reliable information on the safety of herbal medicines as used in Europe and the US. The existing systems were developed for synthetic medicines and require some modification to address the specific differences of medicinal herbs. Traditional medicine from many different cultures is used in Europe and the US which adds to the complexities and difficulties of even basic questions such as herb naming systems and chemical variability. Allied to this also is the perception that a 'natural' or herbal product must be safe simply because it is not synthetic which means that the safety element of monitoring for such medicines can be overlooked because of the tag associated with such products. Cooperation between orthodox physicians and traditional practitioners is needed to bring together the full case details. Independent scientific assistance on toxicological investigation, botanical verification can be invaluable for full evaluation of any case report. Systematic pharmacovigilance is essential to build up reliable information on the safety of herbal medicines for the development of appropriate guidelines for safe effective use.
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Citations
Cited by
Ekor, M. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2013.00177 · Cited by 3,919
Brown, A. C. (2017) · Food and Chemical Toxicology · doi:10.1016/j.fct.2016.11.001 · Cited by 184
Pharmacological Activities of Soursop (Annona muricata Lin.)
Mutakin, M., Fauziati, R., Fadhilah, F. N., Zuhrotun, A., Amalia, R., & Hadisaputri, Y. E. (2022) · Molecules · doi:10.3390/molecules27041201 · Cited by 147
Herbal medicines: challenges in the modern world. Part 4. Canada and United States
Job, K. M., Kiang, T. K. L., Constance, J. E., Sherwin, C. M. T., & Enioutina, E. Y. (2016) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2016.1238762 · Cited by 38
Xu, Y., Patel, D. N., Ng, S.-L. P., Tan, S.-H., Toh, D., Poh, J., Lim, A. T., Chan, C.-L., Low, M.-Y., & Koh, H.-L. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00167 · Cited by 22
Spanakis, M., Bakaros, E., Papadopoulou, S.-N., Fournaraki, A., & Symvoulakis, E. K. (2025) · Pharmacoepidemiology · doi:10.3390/pharma4040022 · Cited by 6
Metadata
- Authors
- Shaw, D., Graeme, L., Pierre, D., Elizabeth, W., & Kelvin, C.
- Venue
- Journal of Ethnopharmacology
- Publisher
- Elsevier BV
- Published
- 2012-04
- Volume
- 140
- Issue
- 3
- Pages
- 513-518
- ISSN
- 0378-8741 (ISSN-L)
- OpenAlex
- W1964598896
- Cited by
- 292
- References
- 0
- FWCI
- 41.45
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.