Ethnomedicinal survey of medicinal plants used in the management of sickle cell disorder in Southern Nigeria
Abstract
Ethnopharmacological relevance The present study entails the medicinal plant species used to manage sickle cell disorder in Southern States of Nigeria. Materials and methods The ethnomedicinal information was gathered through multistage approach from three geopolitical zones of Southern Nigeria, which were purposively selected. Semi-structured questionnaires were administered on 500 respondents in 125 locations. The ethnomedicinal data collected were analyzed using quantitative value indices such as fidelity level (percentage) and use value. The information got was cross checked using literature search and other related materials. Result Five hundred respondents comprising 53.12% females and 46.88% males were observed. It was noted that 26.70% were illiterate while 73.30% had formal education. Seventy-nine percent is traditional healers, 27% herb traders and the other 4% are those who have awareness of sickle cell disease . One hundred and seventy five plant species belonging to 70 families, of which Fabaceae made up 26.76% and Euphorbiaceae 16.90% forming the highest occurrence. It was observed that leaves were the most common plant part used (69.10%) followed by root (15%) and stem bark (14%) in the preparation for sickle cell management. Majority (48.57%) of these plants were harvested from wild with 38.86% being trees. Citrus aurantifolia and Newbouldia laevis had highest use values of 0.69 and 0.64 respectively. Plants with the least use value (0.001) include Abrus canes…
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In Nigeria, there are numerous uses of C. nucifera water in ethnomedicine.
“In Nigeria, there are numerous uses of C. nucifera water in ethnomedicine (Amujoyegbe et al. 2016).”
From Ethnomedicine, improved traditional medicine from Cocos nucifera water and evaluation of antibacterial activity on four bacterial strains in Center, Cameroon (2024) · cites this paper as Amujoyegbe et al. 2016
Cites
Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia
Charache, S., Terrin, M. L., Moore, R. D., Dover, G. J., Barton, F. B., Eckert, S. V., McMahon, R. P., & Bonds, D. R. (1995) · New England Journal of Medicine · doi:10.1056/nejm199505183322001 · Cited by 2,340 · cited 1× · see citing works
“SCD treatment also requires interrupting the interaction of sickle cells with the endothelium (Brugnara et al., 1993; Charache et al., 1995; Kinney et al., 1999; Claster and Vichinsky, 2003; Vadolas et al., 2004).”
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LAMY, G. M. L., LIKENG, J. L. N., NDJIB, R. C., NDOUNGA, S. E. N., ELOMO, L. B., MBUH, S. M., NNANGA, L. S., MAHAMA, M., BIYON, J. B. N., HARMSEN, K., et al. (2024) · Asian Journal of Natural Product Biochemistry · doi:10.13057/biofar/f220104
- Authors
- Amujoyegbe, O. O., Idu, M., Agbedahunsi, J. M., & Erhabor, J. O.
- Affiliations
- University of Benin (NG)
- Obafemi Awolowo University (NG)
- Corresponding author
- Amujoyegbe, O.O.
- Venue
- Journal of Ethnopharmacology
- Publisher
- Elsevier BV
- Published
- 2016-06
- Volume
- 185
- Pages
- 347-360
- ISSN
- 0378-8741 (ISSN-L)
- OpenAlex
- W2310558808
- Cited by
- 66
- References
- 1
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 8 · 2023: 10 · 2022: 8 · 2021: 7 · 2020: 4 · 2019: 10 · 2018: 2 · 2017: 1 · 2015: 1
- FWCI
- 5.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Ethnopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Ethnobotanical and Medicinal Plants Studies
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry Medicinal Plant Applications
- Keywords
- sickle cell disease, medicinal plants, ethnomedicine, traditional medicine, Fabaceae, Euphorbiaceae, Citrus aurantifolia, Newbouldia laevis, use value, fidelity level, Southern Nigeria, plant parts used, wild plant harvesting, traditional healers, herbal medicine
- MeSH terms
- Adult, Aged, Anemia, Sickle Cell, Female, Humans, Male, Phytotherapy, Medicine, Traditional, Middle Aged, Nigeria, Plants, Medicinal, Medicine, African Traditional, Ethnopharmacology, Young Adult
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