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Impact of chitosan composites and chitosan nanoparticle composites on various drug delivery systems: A review
Open accessAbstract
Chitosan is a promising biopolymer for drug delivery systems. Because of its beneficial properties, chitosan is widely used in biomedical and pharmaceutical fields. In this review, we summarize the physicochemical and drug delivery properties of chitosan, selected studies on utilization of chitosan and chitosan-based nanoparticle composites in various drug delivery systems, and selected studies on the application of chitosan films in both drug delivery and wound healing. Chitosan is considered the most important polysaccharide for various drug delivery purposes because of its cationic character and primary amino groups, which are responsible for its many properties such as mucoadhesion, controlled drug release, transfection, in situ gelation, and efflux pump inhibitory properties and permeation enhancement. This review can enhance our understanding of drug delivery systems particularly in cases where chitosan drug-loaded nanoparticles are applied.
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Cites
Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan—a review
George, M., & Abraham, T. E. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.04.017 · Cited by 2,012
Cited by
Rizwan, M., Yahya, R., Hassan, A., Yar, M., Azzahari, A., Selvanathan, V., Sonsudin, F., & Abouloula, C. (2017) · Polymers · doi:10.3390/polym9040137 · Cited by 844
Agrawal, M., Saraf, S., Saraf, S., Antimisiaris, S. G., Chougule, M. B., Shoyele, S. A., & Alexander, A. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.05.011 · Cited by 630
Nanotechnology in food science: Functionality, applicability, and safety assessment
He, X., & Hwang, H.-M. (2016) · Journal of Food and Drug Analysis · doi:10.1016/j.jfda.2016.06.001 · Cited by 474
Harugade, A., Sherje, A. P., & Pethe, A. (2023) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2023.105634 · Cited by 474
Synthesis of chitosan aerogels as promising carriers for drug delivery: A review
Wei, S., Ching, Y. C., & Chuah, C. H. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2019.115744 · Cited by 285
Metadata
- Authors
- Elgadir, M. A., Uddin, M. S., Ferdosh, S., Adam, A., Chowdhury, A. J. K., & Sarker, M. Z. I.
- Venue
- Journal of Food and Drug Analysis
- Published
- 2015-12
- Volume
- 23
- Issue
- 4
- Pages
- 619-629
- ISSN
- 1021-9498 (ISSN-L)
- OpenAlex
- W2061831048
- Cited by
- 536
- References
- 1
- FWCI
- 11.17
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Elgadir, M. A., Uddin, M. S., Ferdosh, S., Adam, A., Chowdhury, A. J. K., & Sarker, M. Z. I. (2015). Impact of chitosan composites and chitosan nanoparticle composites on various drug delivery systems: A review. Journal of Food and Drug Analysis. https://doi.org/10.1016/j.jfda.2014.10.008
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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