Identification of anti-diabetes peptides from Spirulina platensis
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In a study by Hu et al., three synthesized peptides from Limnospira platensis (GVPMPNK, RNPFVFAPTLLTVAAR, and LRSELAAWSR) were evaluated, with LRSELAAWSR showing moderate inhibition of α-amylase and strong inhibition of α-glucosidase.
“In a study by Hu et al. [94], three synthesized peptides from Limnospira platensis, GVPMPNK, RNPFVFAPTLLTVAAR, and LRSELAAWSR, were evaluated, with LRSELAAWSR showing moderate inhibition of α-amylase and strong inhibition of α-glucosidase.”
From Navigating the potential of algal peptides: health effects, market applications, and scientific challenges (2026) · cites this paper as [94]
Limnospira platensis peptide LRSELAAWSR exhibited potent DPP-IV inhibition (IC50 = 167.3 μg/mL).
“Similarly, Limnospira platensis peptide LRSELAAWSR exhibited potent DPP-IV inhibition (IC50 = 167.3 μg/mL) [94].”
From Navigating the potential of algal peptides: health effects, market applications, and scientific challenges (2026) · cites this paper as [94]
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References 34 · Cited by 150
- Authors
- Hu, S., Fan, X., Qi, P., & Zhang, X.
- Affiliations
- South China University of Technology (CN)
- Corresponding author
- Qi, Ping
- Zhang, Xuewu
- Venue
- Journal of Functional Foods
- Publisher
- Elsevier BV
- Published
- 2019-05
- Volume
- 56
- Pages
- 333-341
- ISSN
- 1756-4646 (ISSN-L)
- OpenAlex
- W2924457241
- Cited by
- 150
- References
- 34
- Citations by year
- 2026: 18 · 2025: 24 · 2024: 29 · 2023: 19 · 2022: 12 · 2021: 30 · 2020: 17 · 2019: 1
- FWCI
- 12.21
- Type
- journal article
- Language
- en
- Open access
- green
- doaj.org
- Licence
- Locations
- Journal of Functional Foods (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Administration of Ocean and Fisheries of Guangdong Province
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Keywords
- Spirulina platensis, α-amylase inhibition, α-glucosidase inhibition, DPP-4 inhibition, insulin resistance, HepG2 cells, glycogen metabolism, hexokinase, pyruvate kinase, type 2 diabetes, bioactive peptides
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