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Cited by 298

The DOI matches its Crossref record; 137 of the 137 references it cites were found in a registry or an index.

Proanthocyanidins in grape seeds: An updated review of their health benefits and potential uses in the food industry

Open access
Unusan, Nurhan·2020·Journal of Functional Foods
DOI 10.1016/j.jff.2020.103861
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Abstract

Grape seeds are rich sources of proanthocyanidins, which comprise polyhydroxyflavan oligomers or polymers. The beneficial health properties of grape seed proanthocyanidins are attributed to their conjugated and colonic metabolites. There is potential for a two-way relationship between the gut microbiota and grape seed proanthocyanidin. In particular, numerous in vitro and in vivo studies have demonstrated that grape seed proanthocyanidins appear to exert pharmacological effects. These include anti-oxidant, anti-microbial, anti-obesity, anti-diabetic, anti-neurodegenerative, anti-osteoarthritis, anti-cancer, and cardio- and eye-protective properties. In this review, it is aimed to summarize the current literature regarding grape seed proanthocyanidins, focusing on the recently proposed mechanisms of action from clinical trials considered to underlie pharmacological and disease-preventing properties, along with their bioavailability, toxicology, and safety with regard to potential utilization in the food industry.

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Show all 137 references

Research works printed but not linked: 30

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Cited by

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Metadata

Authors
Unusan, N.
Venue
Journal of Functional Foods
Publisher
Elsevier BV
Published
2020-04
Volume
67
Pages
103861
ISSN
1756-4646 (ISSN-L)
DOI
10.1016/j.jff.2020.103861
OpenAlex
W3008701934
Cited by
298
References
137
FWCI
17.35
Type
journal article
Language
en
Open access
gold
Licence

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Unusan, N. (2020). Proanthocyanidins in grape seeds: An updated review of their health benefits and potential uses in the food industry. Journal of Functional Foods. https://doi.org/10.1016/j.jff.2020.103861

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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