The DOI matches its Crossref record; 157 of the 157 references it cites were found in a registry or an index.
The hazardous threat of Bisphenol A: Toxicity, detection and remediation
Abstract
Bisphenol A (or BPA) is a toxic endocrine disrupting chemical that is released into the environment through modern manufacturing practices. BPA can disrupt the production, function and activity of endogenous hormones causing irregularity in the hypothalamus-pituitary-gonadal glands and also the pituitary-adrenal function. BPA has immuno-suppression activity and can downregulate T cells and antioxidant genes. The genotoxicity and cytotoxicity of BPA is paramount and therefore, there is an immediate need to properly detect and remediate its influence. In this review, we discuss the toxic effects of BPA on different metabolic systems in the human body, followed by its mechanism of action. Various novel detection techniques (LC-MS, GC-MS, capillary electrophoresis, immunoassay and sensors) involving a pretreatment step (liquid-liquid microextraction and molecularly imprinted solid-phase extraction) have also been detailed. Mechanisms of various remediation strategies, including biodegradation using native enzymes, membrane separation processes, photocatalytic oxidation, use of nanosorbents and thermal degradation has been detailed. An overview of the global regulations pertaining to BPA has been presented. More investigations are required on the efficiency of integrated remediation technologies rather than standalone methods for BPA removal. The effect of processing operations on BPA in food matrices is also warranted to restrict its transport into food products.
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Cites
Bisphenol A: An endocrine disruptor with widespread exposure and multiple effects
Rubin, B. S. (2011) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2011.05.002 · Cited by 1,410
Bisphenol A – Sources, toxicity and biotransformation
Michałowicz, J. (2014) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2014.02.003 · Cited by 1,089
Bisphenol A exposure, effects, and policy: A wildlife perspective
Flint, S., Markle, T., Thompson, S., & Wallace, E. (2012) · Journal of Environmental Management · doi:10.1016/j.jenvman.2012.03.021 · Cited by 884
The adverse health effects of bisphenol A and related toxicity mechanisms
Ma, Y., Liu, H., Wu, J., Yuan, L., Wang, Y., Du, X., Wang, R., Marwa, P. W., Petlulu, P., Chen, X., et al. (2019) · Environmental Research · doi:10.1016/j.envres.2019.108575 · Cited by 819
Occurrence, toxicity and ecological risk of Bisphenol A analogues in aquatic environment – A review
Liu, J., Zhang, L., Lu, G., Jiang, R., Yan, Z., & Li, Y. (2021) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.111481 · Cited by 440
Bisphenol-A acts as a potent estrogen via non-classical estrogen triggered pathways
Alonso-Magdalena, P., Ropero, A. B., Soriano, S., García-Arévalo, M., Ripoll, C., Fuentes, E., Quesada, I., & Nadal, Á. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.12.012 · Cited by 358
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Bisphenol A Induces Hepatotoxicity through Oxidative Stress in Rat Model
Hassan, Z. K., Elobeid, M. A., Virk, P., Omer, S. A., ElAmin, M., Daghestani, M. H., & AlOlayan, E. M. (2012) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2012/194829 · Cited by 340
Release of Bisphenol A from Polycarbonate—A Review
Hoekstra, E. J., & Simoneau, C. (2013) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2010.536919 · Cited by 330
Barboza, L. G. A., Cunha, S. C., Monteiro, C., Fernandes, J. O., & Guilhermino, L. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.122419 · Cited by 318
Metadata
- Authors
- Tarafdar, A., Sirohi, R., Balakumaran, P. A., Reshmy, R., Madhavan, A., Sindhu, R., Binod, P., Kumar, Y., Kumar, D., & Sim, S. J.
- Venue
- Journal of Hazardous Materials
- Publisher
- Elsevier BV
- Published
- 2022-02
- Volume
- 423
- Issue
- Pt A
- Pages
- 127097
- ISSN
- 0304-3894 (ISSN-L)
- OpenAlex
- W3197476833
- Cited by
- 361
- References
- 157
- FWCI
- 18.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- Tarafdar, A., Sirohi, R., Balakumaran, P. A., Reshmy, R., Madhavan, A., Sindhu, R., Binod, P., Kumar, Y., Kumar, D., & Sim, S. J. (2022). The hazardous threat of Bisphenol A: Toxicity, detection and remediation. Journal of Hazardous Materials. https://doi.org/10.1016/j.jhazmat.2021.127097
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
