Crosstalk between adipose tissue insulin resistance and liver macrophages in non-alcoholic fatty liver disease

BACKGROUND & AIMS The pathogenesis of Non-Alcoholic Fatty Liver Disease (NAFLD) and steatohepatitis (NASH) is likely due to the interaction between a deranged metabolic milieu and local mediators of hepatic inflammation and fibrosis. We undertook this study to elucidate the interplay between macr…