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Cited by 437

The DOI matches its Crossref record; 522 of the 522 references it cites were found in a registry or an index.

EASL Clinical Practice Guidelines on the management of hepatitis B virus infection

Open access
Cornberg, Markus, Sandmann, Lisa, Jaroszewicz, Jerzy, Kennedy, Patrick, Lampertico, Pietro, Lemoine, Maud, Lens, Sabela, Testoni, Barbara, Lai-Hung Wong, Grace, Russo, Francesco Paolo·2025·Journal of Hepatology

Abstract

The updated EASL Clinical Practice Guidelines on the management of hepatitis B virus (HBV) infection provide comprehensive, evidence-based recommendations for its management. Spanning ten thematic sections, the guidelines address diagnostics, treatment goals, treatment indications, therapeutic options, hepatocellular carcinoma surveillance, management of special populations, HBV reactivation prophylaxis, post-transplant care, HBV prevention strategies, and finally address open questions and future research directions. Chronic HBV remains a global health challenge, with over 250 million individuals affected and significant mortality due to cirrhosis and hepatocellular carcinoma. These guidelines emphasise the importance of early diagnosis, risk stratification based on viral and host factors, and tailored antiviral therapy. Attention is given to simplified algorithms, vaccination, and screening to support global HBV elimination targets. The guidelines also discuss emerging biomarkers and evolving definitions of functional and partial cure. Developed through literature review, expert consensus, and a Delphi process, the guidelines aim to equip healthcare providers across disciplines with practical tools to optimise HBV care and outcomes worldwide.

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Registry

Crossref · 10.1016/j.jhep.2025.03.018

Cites

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Citations

Cites

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Metadata

Authors
Cornberg, M., Sandmann, L., Jaroszewicz, J., Kennedy, P., Lampertico, P., Lemoine, M., Lens, S., Testoni, B., Lai-Hung Wong, G., & Russo, F. P.
Venue
Journal of Hepatology
Publisher
Elsevier BV
Published
2025-08
Volume
83
Issue
2
Pages
502-583
ISSN
0168-8278 (ISSN-L)
OpenAlex
W4410219383
Cited by
437
References
522
FWCI
266.04
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: EASL Clinical Practice Guidelines on the management of hepatitis B virus infection. https://app.cochat.ai/papers/10.1016/j.jhep.2025.03.018
The paper
Cornberg, M., Sandmann, L., Jaroszewicz, J., Kennedy, P., Lampertico, P., Lemoine, M., Lens, S., Testoni, B., Lai-Hung Wong, G., & Russo, F. P. (2025). EASL Clinical Practice Guidelines on the management of hepatitis B virus infection. Journal of Hepatology. https://doi.org/10.1016/j.jhep.2025.03.018

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.