961 Colonization of a 3D skin model with a complete microbiota is more beneficial to the skin barrier than with Staphylococcus epidermidis alone
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Landemaine et al. showed that adding a full skin microbiota collected from the inner forearm of a volunteer to a 3D skin model results in a stable number of bacteria up to 7 days, with a more proliferative epidermis showing higher expression of desmosome and tight junction proteins compared to the same model with only S. epidermidis added.
“This aspect was also underlined by Landemaine et al. [137], who showed that the addition of a full skin microbiota collected from the inner forearm of a volunteer to a 3D skin model results in a stable number of bacteria up to 7 days, with a more proliferative epidermis showing a higher expression of proteins of desmosomes and tight junctions when compared to the same model but with the addition”
From Recreating Human Skin In Vitro: Should the Microbiota Be Taken into Account? (2024) · cites this paper as [137]
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Recreating Human Skin In Vitro: Should the Microbiota Be Taken into Account?
Galvan, A., Pellicciari, C., & Calderan, L. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25021165 · Cited by 11 · see citing works
- Authors
- Landemaine, L., Cenizo, V., Lemaire, G., & Portes, P.
- Venue
- Journal of Investigative Dermatology
- Publisher
- Elsevier BV
- Published
- 2018-05
- Volume
- 138
- Issue
- 5
- Pages
- S163
- ISSN
- 0022-202X (ISSN-L)
- OpenAlex
- W2800142880
- Cited by
- 9
- References
- 0
- Citations by year
- 2025: 1 · 2024: 4 · 2023: 1 · 2021: 2 · 2020: 1
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Investigative Dermatology (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Keywords
- skin microbiome, Staphylococcus epidermidis, 3D skin model, skin barrier, commensal bacteria, atopic dermatitis, Staphylococcus aureus, bacterial colonization, skin barrier integrity
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