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Augmented intelligence dermatology: deep neural networks empower medical professionals in diagnosing skin cancer and predicting treatment options for 134 skin disorders.
Open accessAbstract
Although deep learning algorithms have demonstrated expert-level performance, previous efforts were mostly binary classifications of limited disorders. We trained an algorithm with 220,680 images of 174 disorders and validated it using Edinburgh (1,300 images; 10 disorders) and SNU datasets (2,201 images; 134 disorders). The algorithm could accurately predict malignancy, suggest primary treatment options, render multi-class classification among 134 disorders, and improve the performance of medical professionals. The area under the curves for malignancy detection were 0.928 ± 0.002 (Edinburgh) and 0.937 ± 0.004 (SNU). The area under the curves of primary treatment suggestion (SNU) were 0.828 ± 0.012, 0.885 ± 0.006, 0.885 ± 0.006, and 0.918 ± 0.006 for steroids, antibiotics, antivirals, and antifungals, respectively. For multi-class classification, the mean top-1 and top-5 accuracies were 56.7 ± 1.6% and 92.0 ± 1.1% (Edinburgh) and 44.8 ± 1.2% and 78.1 ± 0.3% (SNU), respectively. With the assistance of our algorithm, the sensitivity and specificity of 47 clinicians (21 dermatologists and 26 dermatology residents) for malignancy prediction (SNU; 240 images) were improved by 12.1% (P < 0.0001) and 1.1% (P < 0.0001), respectively. The malignancy prediction sensitivity of 23 non-medical professionals was significantly increased by 83.8% (P < 0.0001). The top-1 and top-3 accuracies of four doctors in the multi-class classification of 134 diseases (SNU; 2,201 images) were increased by 7.0% (P = 0.045) and 10.1% (P = 0.0020), respectively. The results suggest that our algorithm may serve as augmented intelligence that can empower medical professionals in diagnostic dermatology.
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“the effect of AI-based support on dermoscopic images has been studied.15,24”
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“Several algorithms incorporating artificial intelligence (AI) have been developed to help interpret both clinical11,12,13,14,15 and dermoscopic16,17,18,19,20,21,22,23 images for a variety of skin conditions”
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Metadata
- Authors
- Han, S. S., Park, I., Eun Chang, S., Lim, W., Kim, M. S., Park, G. H., Chae, J. B., Huh, C. H., & Na, J.-I.
- Affiliations
- Chonnam National University (KR)
- LG (South Korea) (KR)
- Inje University (KR)
- Hallym University (KR)
- Seoul National University Bundang Hospital (KR)
- Corresponding author
- Na, Jung-Im
- ORCID
- Venue
- Journal of Investigative Dermatology
- Publisher
- Elsevier BV
- Published
- 2020-09
- Volume
- 140
- Issue
- 9
- Pages
- 1753-1761
- ISSN
- 0022-202X (ISSN-L)
- OpenAlex
- W3014403957
- Cited by
- 248
- References
- 35
- Citations by year
- 2026: 23 · 2025: 43 · 2024: 42 · 2023: 49 · 2022: 55 · 2021: 25 · 2020: 11
- FWCI
- 12.64
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Investigative Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Research Foundation of Korea (2017R1C1B5018396)
- Chonnam National University Hospital Biomedical Research Institute (CRI18019-1 and CRI18094-2)
- Topics
- Health Sciences › Medicine › Oncology › Cutaneous Melanoma Detection and Management
- Physical Sciences › Computer Science › Artificial Intelligence › AI in cancer detection
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Keywords
- ology, skin cancer diagnosis, skin diseases, deep neural network, augmented intelligence, malignancy prediction, non-medical professionals, dermatology education, dermatology residents
- MeSH terms
- Dermatologists, Deep Learning, Adolescent, Adult, Aged, Anti-Bacterial Agents, Antifungal Agents, Antiviral Agents, Clinical Competence, Dermatology, Drug Therapy, Computer-Assisted, Feasibility Studies, Female, Glucocorticoids, Humans, Image Interpretation, Computer-Assisted, Internship and Residency, Male, Middle Aged, Photography, ROC Curve, Skin, Skin Diseases, Skin Neoplasms, Dermoscopy, Young Adult, Datasets as Topic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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