Naturally modified nonionic alginate functionalized upconversion nanoparticles for the highly efficient targeted pH-responsive drug delivery and enhancement of NIR-imaging
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KB cancer cells received effectively DOX-loaded nonionic alginate micelle through folate-mediated endocytosis, resulting in pH-responsive DOX discharge and consequent apoptosis.
“It is noteworthy that KB cancer cells received effectively DOX-loaded nonionic alginate micelle through folate-mediated endocytosis, resulting in pH-responsive DOX discharge and consequent apoptosis, Figure 8B.”
From Recent Advances in Nanomicelles Delivery Systems. (2020) · cites this paper as [17]
90% of DOX was discharged from nonionic alginate nanomicelles at pH 5.0.
“In addition, 90% of DOX was discharged from nanomicelles at pH 5.0 that could be caused by weak ionic interaction between nonionic nanomicelles and DOX.”
From Recent Advances in Nanomicelles Delivery Systems. (2020) · cites this paper as [17]
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References 46 · Cited by 56
- Authors
- Tawfik, S. M., Sharipov, M., Huy, B. T., Gerelkhuu, Z., Biechele-Speziale, D., & Lee, Y.-I.
- Affiliations
- Changwon National University (KR)
- Western Kentucky University (US)
- Corresponding author
- Lee, Yong-Ill
- Venue
- Journal of Industrial and Engineering Chemistry
- Publisher
- Elsevier BV
- Published
- 2018-01
- Volume
- 57
- Pages
- 424-435
- ISSN
- 1226-086X (ISSN-L)
- OpenAlex
- W2752592873
- Cited by
- 56
- References
- 46
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 9 · 2023: 7 · 2022: 9 · 2021: 7 · 2020: 2 · 2019: 8 · 2018: 3 · 2017: 1
- FWCI
- 1.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Industrial and Engineering Chemistry (publishedVersion)
- Funders
- Korea Research Fellowship program funded by the Ministry of Science and ICT (NRF-2015H1D3A1066235)
- Basic Science Program (NRF-2014R1A1A4A01008793)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Physical Sciences › Materials Science › Materials Chemistry › Luminescence Properties of Advanced Materials
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Keywords
- upconversion nanoparticles, pH-responsive drug delivery, doxorubicin, folate receptor targeting, endocytosis, NIR imaging, anticancer drug delivery, biocompatibility, luminescence enhancement
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