Genomic survey of SARS-CoV-2 vaccine breakthrough infections in healthcare workers from Kerala, India
Open accessAbstract
We describe genomic analysis of SARS-CoV-2 isolates from breakthrough infections in six healthcare workers following vaccination with AZD1222/Covishield. Four patients were infected by the variant of concern B.1.1.7 while other isolates possessed E484K and S477N mutations in spike protein associated with immune escape.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Reports have been published in which certain variants of concern were more prevalent in breakthrough infections.
“In contrast, reports in which certain variants of concern were more prevalent in breakthrough infections have been published as well.8,16,26”
From Covid-19 Breakthrough Infections in Vaccinated Health Care Workers (2021) · cites this paper as [26]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
The citation lists haven’t been fetched yet
References 10 · Cited by 62
- Authors
- Philomina J, B., Jolly, B., John, N., Bhoyar, R. C., Majeed, N., Senthivel, V., CP, F., Rophina, M., Vasudevan, B., Imran, M., Viswanathan, P., Arvinden, V. R., Joseph, A., Divakar, M. K., Nair, P. R., Shamnath, A., Kumar, P. J., Jain, A., Geetha, P., Bajaj, A., Mathew, S., Gupta, V., Agrawal, S. J., Scaria, V., Sivasubbu, S., & Radhakrishnan, C.
- Affiliations
- Institute of Genomics and Integrative Biology (IN)
- Government of Kerala (IN)
- Government Medical College (IN)
- Corresponding author
- Scaria, Vinod
- Sivasubbu, Sridhar
- Radhakrishnan, Chandni
- ORCID
- Venue
- Journal of Infection
- Publisher
- Elsevier BV
- Published
- 2021-08
- Volume
- 83
- Issue
- 2
- Pages
- 237-279
- ISSN
- 0163-4453 (ISSN-L)
- PMC
- PMC8143909
- OpenAlex
- W3164217743
- Cited by
- 62
- References
- 10
- Citations by year
- 2024: 2 · 2023: 7 · 2022: 36 · 2021: 16
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Infection (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- OSF Preprints (OSF Preprints) (submittedVersion, cc-by)
- OSF Preprints (OSF Preprints) (submittedVersion)
- Funders
- Council of Scientific & Industrial Research
- Topics
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
- Keywords
- SARS-CoV-2, COVID-19 breakthrough infection, vaccine breakthrough infection, healthcare workers, B.1.1.7 variant, spike protein variants, E484K, SARS-CoV-2 genomics
- MeSH terms
- COVID-19, SARS-CoV-2, COVID-19 Vaccines, Antibody Formation, Health Personnel, Humans, India, RNA, Messenger, Genomics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
