The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
To an understanding of the biology of sex and gender differences: “an idea whose time has come
Abstract
Abstract In 2001 the Institute of Medicine of the National Academy of Sciences United States published a report, “Exploring the Biological Contributions to Human Health: Does Sex Matter?”, which addressed and highlighted the role of biological sex differences in health and disease, including especially sex differences in non-reproductive areas of the male and female. The report aroused considerable interest and comment and had a significant role in stimulating the generation of a growing body of basic and clinical research on fundamental aspects of sex differences and its role in disease susceptibility, development, and aging. Sex is the most common human polymorphism that affects health and illness through the life cycle. This perspective provides a brief overview of the importance of the critical interlinked interactions of nature (genes and sex hormones) and nurture (environment and experience) on behavior and perception. Differences in gene expression in the male and female appear in the early embryo,...
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Williams Textbook of Endocrinology
Melmed, S., & Polonsky, K. S. (2016) · Elsevier eBooks · doi:10.1016/c2013-0-15980-6 · Cited by 3,715
The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes
Skaletsky, H., Kuroda-Kawaguchi, T., Minx, P. J., Cordum, H. S., Hillier, L., Brown, L. G., Repping, S., Pyntikova, T., Ali, J., Bieri, T. A., et al. (2003) · Nature · doi:10.1038/nature01722 · Cited by 2,148
An abundance of X-linked genes expressed in spermatogonia
Wang, P. J., McCarrey, J. R., Yang, F., & Page, D. C. (2001) · Nature Genetics · doi:10.1038/86927 · Cited by 784
Exploring the Biological Contributions to Human Health
Institute of Medicine (2001) · National Academies Press eBooks · doi:10.17226/10028 · Cited by 658
Sex Differences in Pharmacokinetics and Pharmacodynamics
Gandhi, M., Aweeka, F. T., Greenblatt, R. M., & Blaschke, T. F. (2004) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.44.101802.121453 · Cited by 546
Estrogen: Consequences and Implications of Human Mutations in Synthesis and Action
Grumbach, M. M., & Auchus, R. J. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.12.6290 · Cited by 412
Self-citationDisorders of sex differentiation
Grumbach, M. M. (1992) · Medical Entomology and Zoology · Cited by 402
Self-citationSexually dimorphic gene expression in mouse brain precedes gonadal differentiation
Dewing, P., Shi, T., Horvath, S., & Vilain, E. J. N. (2003) · Molecular Brain Research · doi:10.1016/s0169-328x(03)00339-5 · Cited by 359
A first-generation X-inactivation profile of the human X chromosome
Carrel, L., Cottle, A. A., Goglin, K. C., & Willard, H. F. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.25.14440 · Cited by 354
The ‘oestrogen hypothesis’– where do we stand now?1
Sharpe, R. M. (2003) · International Journal of Andrology · doi:10.1046/j.1365-2605.2003.00367.x · Cited by 330
Sex Differences in Mortality Rate
Owens, I. P. F. (2002) · Science · doi:10.1126/science.1076813 · Cited by 279
Zechner, U., Wilda, M., Kehrer‐Sawatzki, H., Vogel, W., Fundele, R., & Hameister, H. (2001) · Trends in Genetics · doi:10.1016/s0168-9525(01)02446-5 · Cited by 274
Sex differences in sex chromosome gene expression in mouse brain
Xu, J. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.12.1409 · Cited by 269
Gender-Specific Gene Expression in Post-Mortem Human Brain: Localization to Sex Chromosomes
Vawter, M. P., Evans, S. J., Choudary, P. V., Tomita, H., Meador-Woodruff, J., Molnar, M., Li, J. Z., López, J. F., Myers, R. M., Cox, D. R., et al. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300337 · Cited by 204
Are XX and XY brain cells intrinsically different?
Arnold, A. P., & Burgoyne, P. S. (2003) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2003.11.001 · Cited by 166
Evidence That the Human X Chromosome Is Enriched for Male-Specific but not Female-Specific Genes
Lercher, M. J. (2003) · Molecular Biology and Evolution · doi:10.1093/molbev/msg131 · Cited by 125
COMMITTEE ON UNDERSTANDING THE BIOLOGY OF SEX AND GENDER DIFFERENCES
Differences, G., Wizemann, T. M., & Pardue, M. (2001) · Cited by 54
Sexual dimorphism in the neonatal gonad
Hughes, I. A., Coleman, N., Ahmed, S. F., Ng, K., Cheng, A. W.-F., Lim, H. N., & Hawkins, J. (1999) · Acta Paediatrica · doi:10.1111/j.1651-2227.1999.tb14347.x · Cited by 21
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Where Sex Meets Gender: How Sex and Gender Come Together to Cause Sex Differences in Mental Illness
Christiansen, D. M., McCarthy, M. M., & Seeman, M. V. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.856436 · Cited by 65
“They also serve important regulatory functions in relation to neurotransmitter systems (94).”
Background
Metadata
- Authors
- Grumbach, M. M.
- Corresponding author
- Grumbach, Melvin M.
- Venue
- The Journal of Men's Health & Gender
- Publisher
- SAGE Publications
- Published
- 2004-05
- Volume
- 1
- Issue
- 1
- Pages
- 12-19
- ISSN
- 1571-8913 (ISSN-L)
- OpenAlex
- W2162220716
- Cited by
- 10
- References
- 18
- Citations by year
- 2022: 1 · 2014: 1 · 2012: 1
- FWCI
- 1.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Men s Health and Gender (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Keywords
- sex differences, gender differences, sex hormones, gene expression, nature versus nurture, sex differences in disease susceptibility, aging, development (biology), human polymorphism, sex differences in health
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