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Cited by 44Bone Tissue Engineering Materialsbiodegradable polymer synthesis and propertiesSurface Treatment and Coatings

Dielectric and biodegradation properties of biodegradable nano-hydroxyapatite/starch bone scaffold

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You, Beh Chong, Meng, Cheng Ee, Mohd Nasir, Nashrul Fazli, Mohd Tarmizi, Emma Ziezie, Fhan, Khor Shing, Kheng, Eng Swee, Abdul Majid, Mohd Shukry, Mohd Jamir, Mohd Ridzuan·2022·Journal of Materials Research and Technology
DOI 10.1016/j.jmrt.2022.04.014
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Abstract

This study is aim to investigate the dielectric properties (dielectric constant, ε′ and loss factor, ε′′) and the biodegradation properties of the nano-hydroxyapatite/starch bone scaffold with various starch proportion in simulated body fluid. The nano-hydroxyapatite/starch bone scaffolds with starch proportions 30, 40, 50, 60, 70, 80, and 90 wt.% were fabricated. The ε′ and ε′′ of nano-hydroxyapatite/starch composite decrease when frequency increases. However, it increases when starch proportion and temperature increase. The biodegradation properties of the nano-hydroxyapatite/starch bone scaffold can be improved when the dielectric properties and porosity are enhanced. The enhancement of dielectric properties and porosity is due to the increment of starch proportion. The nano-hydroxyapatite/starch bone scaffold with the high starch proportion exhibits nano-hydroxyapatite/starch interfaces with strong intermolecular interactions that can stabilize biodegradation and biomineralization. The dielectric properties of the simulated body solutions are highly sensitive to the variation of the ion concentrations (calcium and phosphate). The nano-hydroxyapatite/starch bone scaffold with 80 wt.% starch proportion exhibits significant dielectric and biodegradation properties. It has potential to be a biodegradable inorganic/organic bone scaffold.

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  • Biodegradable matrices recommended for hard tissue tissue engineering must be uniformly degraded in the human body during bone mineralization to improve bone tissue replacement and growth processes.

    “Biodegradable matrices recommended for hard tissue TE must be uniformly degraded in the human body during bone mineralization to improve bone tissue replacement and growth processes [77].”

    From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [77]

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Cited by

Sorted by citations

Authors
You, B. C., Meng, C. E., Mohd Nasir, N. F., Mohd Tarmizi, E. Z., Fhan, K. S., Kheng, E. S., Abdul Majid, M. S., & Mohd Jamir, M. R.
Affiliations
Universiti Malaysia Perlis (MY)
ORCID
Venue
Journal of Materials Research and Technology
Publisher
Elsevier BV
Published
2022-05
Volume
18
Pages
3215-3226
ISSN
  • 2214-0697 (ISSN-L)
  • 2238-7854
DOI
10.1016/j.jmrt.2022.04.014
OpenAlex
W4224257152
Cited by
44
References
0
Citations by year
2026: 4 · 2025: 6 · 2024: 15 · 2023: 16 · 2022: 3
FWCI
2.86
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Materials Research and Technology (publishedVersion, cc-by-nc-nd)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia) (submittedVersion, cc-by-nc-nd)
Funders
Ministry of Higher Education, Malaysia (RACER/1/2019/STG07/UNIMAP/2)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
  • Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
  • Physical Sciences › Engineering › Mechanical Engineering › Surface Treatment and Coatings
Keywords
hydroxyapatite nanoparticles, starch, bone scaffolds, dielectric properties, biodegradation, simulated body fluid, porosity, biomineralization, calcium and phosphate ions, biodegradable bone substitutes

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