Tickets to the brain: Role of CCR2 and CX3CR1 in myeloid cell entry in the CNS

Myeloid cells are mediators of central nervous system (CNS) damage and recovery in neuroinflammatory and neurodegenerative disorders. Besides endogenous myelomonocytic cell populations that reside in the brain already during development, newly migrated leukocytes are considered as important disea…