The DOI matches its Crossref record.
Iowa APP mutation-related hereditary cerebral amyloid angiopathy (CAA): A new family from Spain
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APP mutations can lead to cerebrovascular pathology including BBB breakdown and cerebral amyloid angiopathy in humans and transgenic animal models expressing human APP mutations.
“APP mutations can lead to cerebrovascular pathology including BBB breakdown and cerebral amyloid angiopathy (CAA), as shown in humans (49, 211, 356, 674) and transgenic animal models expressing human APP mutations (56, 57, 137, 321, 322, 331, 336, 405, 420, 464, 467, 512, 513, 579, 606).”
From Blood-Brain Barrier: From Physiology to Disease and Back (2019) · cites this paper as [674]
Individuals with vasculotropic APP mutations within Aβ 21-23 residues, including Dutch, Arctic, Flemish, Iowa, and Italian mutations, develop prominent CAA causing extensive cerebrovascular pathology.
“Individuals with 'vasculotropic' APP mutations within A 𝛃 21-23 residues including Dutch (E693Q), Arctic (E693G), Flemish (A692G), Iowa (D694N), and Italian (E693K) mutation (49, 211, 335, 356, 526, 674) develop prominent CAA (238, 640) causing extensive cerebrovascular pathology.”
From Blood-Brain Barrier: From Physiology to Disease and Back (2019) · cites this paper as [674]
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 6
- Iwanowski, 2015, Iowa-type hereditary cerebral amyloid angiopathy in a Polish family, J. Neurol. Sci., 356, 202, 10.1016/j.jns.2015.06.020 · DOI
- Iglesias, 2000, Familial occipital calcifications, hemorrhagic strokes, leukoencephalopathy, dementia, and external carotid dysplasia, Neurology, 55, 1661, 10.1212/WNL.55.11.1661 · DOI
- Greenberg, 2003, Hemorrhagic stroke associated with the Iowa amyloid precursor protein mutation, Neurology, 60, 1020, 10.1212/01.WNL.0000050140.10044.A8 · DOI
- Grabowski, 2001, Novel amyloid precursor protein mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy, Annals of Neurology., 49, 697, 10.1002/ana.1009 · DOI · Paper page
- Mok, 2014, Familial cerebral amyloid angiopathy due to the iowa mutation in an Irish family, Can. J. Neurol. Sci., 41, 512, 10.1017/S031716710001859X · DOI
- Mackenzie, 1997, Cerebral amyloid angiopathy with extensive mineralization, Clin. Neuropathol., 16, 209
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Blood-Brain Barrier: From Physiology to Disease and Back
Sweeney, M. D., Zhao, Z., Montagne, A., Nelson, A. R., & Zlokovic, B. V. (2019) · Physiological Reviews · doi:10.1152/physrev.00050.2017 · Cited by 2,312
Metadata
- Authors
- Zarranz, J. J., Fernandez-Martinez, M., Rodriguez, O., Mateos, B., Iglesias, S., & Baron, J.-C.
- Affiliations
- Hospital de Cruces (ES)
- Inserm (FR)
- Corresponding author
- Baron, J.-C.
- ORCID
- Baron, J.-C.
- Venue
- Journal of the Neurological Sciences
- Publisher
- Elsevier BV
- Published
- 2016-04
- Volume
- 363
- Pages
- 55-56
- ISSN
- 0022-510X (ISSN-L)
- OpenAlex
- W2259588464
- Cited by
- 14
- References
- 0
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2020: 4 · 2019: 2 · 2018: 1 · 2016: 1
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the Neurological Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Intracerebral and Subarachnoid Hemorrhage Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Clinical Neurology › Cerebrovascular and genetic disorders
- Keywords
- hereditary cerebral amyloid angiopathy, APP mutations, amyloid precursor protein, hemorrhagic stroke, Basque families, genetic diagnosis
- MeSH terms
- Family Health, Female, Humans, Male, Cerebral Amyloid Angiopathy, Familial
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