Treatment of symptomatic knee osteoarthritis with oral salmon calcitonin: results from two phase 3 trials

Karsdal, M.A.; Byrjalsen, I.; Alexandersen, P.; Bihlet, A.; Andersen, J.R.; Riis, B.J.; Bay-Jensen, A.C.; Christiansen, C.

doi:10.1016/j.joca.2014.12.019

Treatment of symptomatic knee osteoarthritis with oral salmon calcitonin: results from two phase 3 trials

PURPOSE To evaluate the structure-modifying and symptom efficacy, as well as safety and tolerability of oral salmon calcitonin (sCT) formulated with a 5-CNAC carrier (a molecule based on Eligen(®) technology), in osteoarthritis (OA) patients with moderate to severe knee pain and joint structural …