The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Correlation between Clinical and Histologic Pulp Diagnoses
Abstract
Introduction Clinicians routinely face conditions in which they have to decide whether the dental pulp can be saved or not. This study evaluated how reliable the clinical diagnosis of normal pulp/reversible pulpitis (savable pulp) or irreversible pulpitis (nonsavable pulp) is when compared with the histologic diagnosis. Methods The study material consisted of 95 teeth collected consecutively in a general practice over a 5-year period and extracted for reasons not related to this study. Based on clinical criteria, teeth were categorized as having normal pulps, reversible pulpitis, or irreversible pulpitis. The former 2 were grouped together because they represent similar conditions in terms of prognosis. Teeth were processed for histologic and histobacteriologic analyses, and pulps were categorized as healthy, reversibly inflamed, or irreversibly inflamed according to defined criteria. The number of matching clinical/histologic diagnosis was recorded. Results The clinical diagnosis of normal pulp/reversible pulpitis matched the histologic diagnosis in 57 of 59 (96.6%) teeth. Correspondence of the clinical and histologic diagnosis of irreversible pulpitis occurred in 27 of 32 (84.4%) cases. Infection advancing to the pulp tissue was a common finding in teeth with irreversible pulpitis but was never observed in normal/reversibly inflamed pulps. Conclusions Findings using defined criteria for clinical and histologic classification of pulp conditions revealed a good agreement, especially for cases with no disease or reversible disease. This means that the classification of pulp conditions as normal pulps, reversible pulpitis, and irreversible pulpitis has high chances of guiding the correct therapy in the large majority of cases. However, there is still a need for refined and improved means for reliable pulp diagnosis.
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“Future research should focus on establishing clearer correlations between clinical symptoms and histological status of the pulp, as current evidence shows significant discrepancies between these parameters [25].”
From Consensus‐Based Recommendations on Pulp Therapies in Primary and Permanent Teeth: IAPD Porto Forum (2026) · cites this paper as [25]
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Cites
Clinical signs and symptoms in pulp disease
DUMMER, P. M. H., HICKS, R., & HUWS, D. (1980) · International Endodontic Journal · doi:10.1111/j.1365-2591.1980.tb00834.x · Cited by 282
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Research works printed but not linked: 15
- Abbott, 2007, A clinical classification of the status of the pulp and the root canal system, Aust Dent J, 52, S17, 10.1111/j.1834-7819.2007.tb00522.x · DOI
- Baume, 1970, Diagnosis of diseases of the pulp, Oral Surg Oral Med Oral Pathol, 29, 102, 10.1016/0030-4220(70)90416-0 · DOI
- Seltzer, 1963, The dynamics of pulp inflammation: correlations between diagnostic data and actual histologic findings in the pulp, Oral Surg Oral Med Oral Pathol, 16, 846, 10.1016/0030-4220(63)90323-2 · DOI
- Garfunkel, 1973, Dental pulp pathosis. Clinicopathologic correlations based on 109 cases, Oral Surg Oral Med Oral Pathol, 35, 110, 10.1016/0030-4220(73)90101-1 · DOI
- Johnson, 1970, Pulpal hyperemia—a correlation of clinical and histologic data from 706 teeth, J Am Dent Assoc, 81, 108, 10.14219/jada.archive.1970.0132 · DOI
- Reeves, 1966, The relationship of bacterial penetration and pulpal pathosis in carious teeth, Oral Surg Oral Med Oral Pathol, 22, 59, 10.1016/0030-4220(66)90143-5 · DOI
- Langeland, 1987, Tissue response to dental caries, Endod Dent Traumatol, 3, 149, 10.1111/j.1600-9657.1987.tb00619.x · DOI
- Ricucci, 2010, Fate of the tissue in lateral canals and apical ramifications in response to pathologic conditions and treatment procedures, J Endod, 36, 1, 10.1016/j.joen.2009.09.038 · DOI
- Levin, 2009, Identify and define all diagnostic terms for pulpal health and disease states, J Endod, 35, 1645, 10.1016/j.joen.2009.09.032 · DOI
- Mejàre, 2012, Diagnosis of the condition of the dental pulp: a systematic review, Int Endod J, 45, 597, 10.1111/j.1365-2591.2012.02016.x · DOI · Paper page
- Taylor, 1966, Modification of the Brown and Brenn Gram stain for the differential staining of gram-positive and gram-negative bacteria in tissue sections, Am J Clin Pathol, 46, 472, 10.1093/ajcp/46.4.472 · DOI
- Ricucci, 2003, Bacterial status in root-filled teeth exposed to the oral environment by loss of restoration and fracture or caries—a histobacteriological study of treated cases, Int Endod J, 36, 787, 10.1046/j.1365-2591.2003.00721.x · DOI
- Barthel, 2000, Pulp capping of carious exposures: treatment outcome after 5 and 10 years: a retrospective study, J Endod, 26, 525, 10.1097/00004770-200009000-00010 · DOI
- Hyman, 1984, The predictive value of endodontic diagnostic tests, Oral Surg Oral Med Oral Pathol, 58, 343, 10.1016/0030-4220(84)90065-3 · DOI
- Lundy, 1969, Correlation of pulpal histopathology and clinical symptoms in human teeth subjected to experimental irritation, Oral Surg Oral Med Oral Pathol, 27, 187, 10.1016/0030-4220(69)90172-8 · DOI
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Duncan, H. F., Galler, K., Tomson, P., Simon, S., karim, I. E., Kundzina, R., Krastl, G., Dammaschke, T., Fransson, H., Markvart, M., et al. (2019) · International Endodontic Journal · doi:10.1111/iej.13080 · Cited by 644
“1980); however, this has recently been questioned (Ricucci et al. 2014).”
BackgroundParirokh, M., Torabinejad, M., & Dummer, P. (2018) · International Endodontic Journal · doi:10.1111/iej.12841 · Cited by 456
Management of deep caries and the exposed pulp.
Bjørndal, L., Simon, S., Tomson, P., & Duncan, H. F. (2019) · International Endodontic Journal · doi:10.1111/iej.13128 · Cited by 444
Duncan, H. F., Kirkevang, L., Peters, O. A., El‐Karim, I., Krastl, G., Del Fabbro, M., Chong, B. S., Galler, K. M., Segura‐Egea, J. J., Kebschull, M., et al. (2023) · International Endodontic Journal · doi:10.1111/iej.13974 · Cited by 304
Wolters, W. J., Duncan, H. F., Tomson, P. L., Karim, I. E., McKenna, G., Dorri, M., Stangvaltaite, L., & van der Sluis, L. W. M. (2017) · International Endodontic Journal · doi:10.1111/iej.12793 · Cited by 298
“Furthermore, endodontically treated teeth without visible radiographic signs of apical periodontitis can still be infected (Molander et al. 1998, Ricucci et al. 2014).”
BackgroundInfluential
Metadata
- Authors
- Ricucci, D., Loghin, S., & Siqueira, J. F.
- Affiliations
- Estácio (Brazil) (BR)
- Corresponding author
- Ricucci, Domenico
- Venue
- Journal of Endodontics
- Publisher
- Elsevier BV
- Published
- 2014-12
- Volume
- 40
- Issue
- 12
- Pages
- 1932-1939
- ISSN
- 0099-2399 (ISSN-L)
- OpenAlex
- W2079366348
- Cited by
- 477
- References
- 0
- Citations by year
- 2026: 60 · 2025: 58 · 2024: 77 · 2023: 61 · 2022: 55 · 2021: 43 · 2020: 39 · 2019: 28 · 2018: 18 · 2017: 13 · 2016: 17 · 2015: 7
- FWCI
- 14.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Endodontics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Dentistry › Oral Surgery › Endodontics and Root Canal Treatments
- Health Sciences › Dentistry › General Dentistry › Dental materials and restorations
- Health Sciences › Dentistry › General Dentistry › Oral Health Pathology and Treatment
- Keywords
- diagnosis, histopathological diagnosis, pulp diagnosis, reversible pulpitis, irreversible pulpitis, pulpitis, pulp infection, endodontic treatment
- MeSH terms
- Adolescent, Adult, Aged, Bacteria, Composite Resins, Dental Amalgam, Dental Caries, Dental Materials, Dental Pulp, Dental Pulp Necrosis, Dental Pulp Test, Dental Restoration, Permanent, Dentin, Dentin, Secondary, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Odontoblasts, Prognosis, Pulpitis, Young Adult
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