Siyakhana: A hybrid type 2 effectiveness-implementation stepped-wedge trial to reduce stigma towards substance use and depression among community health workers in HIV/TB care in South Africa

Magidson, Jessica F.; Regenauer, Kristen S.; Johnson, Kim; Ma, Tianzhou; Belus, Jennifer M.; Rose, Alexandra L.; Brown, Imani; Ciya, Nonceba; Ndamase, Sibabalwe; Sacko, Caroline; Joska, John; Sibeko, Goodman; Bassett, Ingrid V.; Myers, Bronwyn

doi:10.1016/j.josat.2025.209634

Siyakhana: A hybrid type 2 effectiveness-implementation stepped-wedge trial to reduce stigma towards substance use and depression among community health workers in HIV/TB care in South Africa

Introduction: Substance use (SU) and other mental health conditions, such as depression, contribute to poor engagement in HIV and TB care in South Africa, a country with the highest global prevalence of HIV and a significant TB burden. Yet, community health workers (CHWs)—frontline lay health wor…