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Cited by 33Magnesium Alloys: Properties and ApplicationsSurface Treatment and CoatingsTitanium Alloys Microstructure and Properties

Polymer bilayer-Micro arc oxidation surface coating on pure magnesium for bone implantation

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Dong, Jieyang, Zhong, Jiaqi, Hou, Ruixia, Hu, Xiaodong, Chen, Yujiong, Weng, Hangbin, Zhang, Zhewei, Liu, Botao +2 more·2023·Journal of Orthopaedic Translation
DOI 10.1016/j.jot.2023.05.003PMC PMC10232471
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Abstract

Pure magnesium-based ortho-implants have a number of advantages. However, vital parameters like degradation rate and biocompatibility still call for significant improvement. In this study, poly (1,3-trimethylene carbonate) (PTMC) and polydopamine (PDA) bilayer and micro arc oxidation composite coatings were prepared successively on magnesium surface by immersion method and microarc oxidation. Its corrosion resistance and biocompatibility were evaluated by in vitro corrosion tests, cellular compatibility experiments, and in vivo animal experiments. In vitro experiments demonstrated that the composite coating provides excellent corrosion protection and biocompatibility. Animal studies demonstrated that the composite coating slowed the degradation of the implant and was not toxic to animal viscera. In conclusion, the inorganic-organic composite coating proposed in this study provided good corrosion resistance and enhanced biocompatibility for pure magnesium implants. The translational potential of this article is to develop an anti-corrosion composite coating on a pure magnesium surface and to verify the viability of its use in animal models. It is hoped to open up a new approach to the design of new degradable orthopedic magnesium-based implants.

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Cited by

Sorted by citations

Authors
Dong, J., Zhong, J., Hou, R., Hu, X., Chen, Y., Weng, H., Zhang, Z., Liu, B., Yang, S., & Peng, Z.
Affiliations
  • Ningbo University (CN)
  • Shanghai Jiao Tong University (CN)
Corresponding author
  • Hou, Ruixia
  • Yang, Shengbing
  • Peng, Zhaoxiang
ORCID
Venue
Journal of Orthopaedic Translation
Publisher
Elsevier BV
Published
2023-05
Volume
40
Pages
27-36
ISSN
2214-031X (ISSN-L)
DOI
10.1016/j.jot.2023.05.003
PMC
PMC10232471
OpenAlex
W4378070503
Cited by
33
References
1
Citations by year
2026: 7 · 2025: 10 · 2024: 11 · 2023: 5
FWCI
2.11
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Orthopaedic Translation (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Medical Science and Technology Project of Zhejiang Province (2022KY1083)
  • Zhejiang Province Public Welfare Technology Application Research Project (LGF21H060003)
  • Science and Technology Innovation 2025 Major Project of Ningbo (2019B10064)
Topics
  • Physical Sciences › Materials Science › Biomaterials › Magnesium Alloys: Properties and Applications
  • Physical Sciences › Engineering › Mechanical Engineering › Surface Treatment and Coatings
  • Physical Sciences › Materials Science › Materials Chemistry › Titanium Alloys Microstructure and Properties
Keywords
plasma electrolytic oxidation, polydopamine, double-layer coating, corrosion resistance, biocompatibility, degradation rate, bone implants

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