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Cited by 274Opioid Use Disorder TreatmentSubstance Abuse Treatment and OutcomesPain Management and Opioid Use

The DOI matches its Crossref record; 49 of the 50 references it cites were found in a registry or an index.

Substance Use Disorders in a Primary Care Sample Receiving Daily Opioid Therapy

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Fleming, Michael F., Balousek, Stacey L., Klessig, Cynthia L., Mundt, Marlon P., Brown, David D.·2007·The Journal of Pain
DOI 10.1016/j.jpain.2007.02.432PMC PMC1959336
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Abstract

Unlabelled The primary goal of this paper was to present a comprehensive picture of substance use disorders in a sample of patients receiving opioid therapy from their primary care physician. A second goal was to determine the relation of positive urine screens and aberrant drug behaviors to opioid use disorders. The study recruited 801 adults receiving daily opioid therapy from the primary care practices of 235 family physicians and internists in 6 health care systems in Wisconsin. The 6 most common pain diagnoses were degenerative arthritis, low back pain, migraine headaches, neuropathy, and fibromyalgia. The point prevalence of current (DSM-IV criteria in the past 30 days) substance abuse and/or dependence was 9.7% (n=78) and 3.8% (30) for an opioid use disorder. A logistic regression model found that current substance use disorders were associated with age between 18 and 30 (OR=6.17: 1.99 to 19.12), severity of lifetime psychiatric disorders (OR=6.17; 1.99 to 19.12), a positive toxicology test for cocaine (OR=5.92; 2.60 to 13.50) or marijuana (OR=3.52; 1.85 to 6.73), and 4 aberrant drug behaviors (OR=11.48; 6.13 to 21.48). The final model for opioid use disorders was limited to aberrant behaviors (OR=48.27; 13.63 to 171.04) as the other variables dropped out of the model. Perspective This study found that the frequency of opioid use disorders was 4 times higher in patients receiving opioid therapy compared with general population samples (3.8% vs 0.9%). The study also pro…

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Crossref · 10.1016/j.jpain.2007.02.432

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Research works printed but not linked: 2

  1. Portenoy, 1990, Chronic opioid therapy in non malignant pain, J Pain Symptom Manage, 5, S46
  2. Wilson, 2002, Opioid use and diversion: report on recent hearing by FDA and DEA: ASA statement to FDA committee, ASA Newsletter, 66, 9

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Metadata

Authors
Fleming, M. F., Balousek, S. L., Klessig, C. L., Mundt, M. P., & Brown, D. D.
Affiliations
  • University of Wisconsin–Madison (US)
  • University of British Columbia (CA)
Corresponding author
Fleming, Michael F.
ORCID
Venue
The Journal of Pain
Publisher
Elsevier BV
Published
2007-07
Volume
8
Issue
7
Pages
573-582
ISSN
1526-5900 (ISSN-L)
DOI
10.1016/j.jpain.2007.02.432
PMC
PMC1959336
OpenAlex
W2010125810
Cited by
274
References
50
Citations by year
2026: 1 · 2025: 1 · 2024: 3 · 2023: 8 · 2022: 8 · 2021: 10 · 2020: 13 · 2019: 16 · 2018: 14 · 2017: 22 · 2016: 15 · 2015: 17 · 2014: 19 · 2013: 19 · 2012: 20
FWCI
22.05
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Pain (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institute on Alcohol Abuse and Alcoholism (T32AA014845)
  • National Institute on Drug Abuse (R01DA013686)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Keywords
opioid use disorder, substance use disorders, primary care, cocaine use, cannabis use, psychiatric comorbidity, chronic pain
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Analgesics, Opioid, Marijuana Abuse, Chronic Disease, Drug Administration Schedule, Humans, Mass Screening, Middle Aged, Opioid-Related Disorders, Pain, Intractable, Intractable Pain, Physicians, Family, Risk Factors, Comorbidity, Causality, Prevalence, Logistic Models, Urinalysis, Substance-Related Disorders, Cocaine-Related Disorders

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