Combined application of dispersive liquid–liquid microextraction based on the solidification of floating organic droplets and charged aerosol detection for the simple and sensitive quantification of macrolide antibiotics in human urine

Jia, Shaodong; Li, Jing; Park, So-Ra; Ryu, Yeonsuk; Park, Il Ho; Park, Jeong Hill; Hong, Soon-Sun; Kwon, Sung Won; Lee, Jeongmi

doi:10.1016/j.jpba.2013.07.024

Combined application of dispersive liquid–liquid microextraction based on the solidification of floating organic droplets and charged aerosol detection for the simple and sensitive quantification of macrolide antibiotics in human urine

A novel analytical method combining dispersive liquid-liquid microextraction based on the solidification of floating organic droplets (DLLME-SFO) and liquid chromatography with charged aerosol detection (LC-CAD) was established. For the first time, CAD was applied for the detection of macrolide a…