NIR Spectroscopy of Natural Medicines Supported by Novel Instrumentation and Methods for Data Analysis and Interpretation
Open accessAbstract
Near-infrared (NIR) spectroscopy is a powerful tool for qualitative and quantitative phytoanalysis. It is a rapid and high-throughput analytical method, with on-site capability, high chemical specificity, and no/minimal sample preparation. NIR spectroscopy is a powerful non-invasive and low-cost alternative with significant practical advantages compared to the conventional methods of analysis. These advantages are particularly exposed in the field of phytoanalysis. In contrast to synthetic medicines, natural products feature chemical diversity that can vary depending on the medicinal plant cultivation conditions, geographical origin or harvest time. The content of bioactive compounds and their derivatives, and thus, the quality parameters of the natural medicine need to be controlled with respect to a number of conditions. NIR spectroscopy has been proved to be particularly competitive in such difficult scenarios. In recent years, remarkable advances in the field of spectroscopic instrumentation and methods of analysis have appeared. Noteworthy was the appearance and dynamic continuing development of miniaturized, on-site capable NIR spectrometers. This was accompanied by application of new tools increasing the potential and reliability of NIR spectroscopy in phytoanalytical applications. The present review discussed the major principles of this technique and critically assesses its future application potential in phytoanalytical strategies. Major attention is given to the current development trends based on the most recent literature published in the field.
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FT-NIR is a spectroscopic technique widely used in the authentication of herbal products and agricultural products, as well as in numerous natural product analyses.
“FT-NIR is a spectroscopic technique that has been widely using in the authentication of herbal products and agricultural products, as well as in numerous natural product analyses [25,28].”
From Comprehensive Metabolomic Fingerprinting Combined with Chemometrics Identifies Species- and Variety-Specific Variation of Medicinal Herbs: An Ocimum Study (2023) · cites this paper as [28]
Section 3.6 says NIR spectroscopy has a long tradition in authenticating herbal medicines, and the Introduction describes its use in quality assessment and analysis of plant-derived natural products. Section 2.2 identifies Fourier-transform instruments as a common benchtop NIR design. The cited paper does not establish the claim that FT-NIR is widely used specifically to authenticate agricultural products. (LLM, conf=0.86)
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References 83 · Cited by 81
Research works printed but not linked: 6
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- Authors
- Beć, K. B., Grabska, J., & Huck, C. W.
- Affiliations
- Universität Innsbruck (AT)
- Corresponding author
- Huck, Christian W.
- Venue
- Journal of Pharmaceutical and Biomedical Analysis
- Publisher
- Elsevier BV
- Published
- 2021-01
- Volume
- 193
- Pages
- 113686
- ISSN
- 0731-7085 (ISSN-L)
- OpenAlex
- W3093703530
- Cited by
- 81
- References
- 83
- Citations by year
- 2026: 11 · 2025: 15 · 2024: 13 · 2023: 13 · 2022: 19 · 2021: 9 · 2020: 1
- FWCI
- 1.39
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Pharmaceutical and Biomedical Analysis (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Digital Library of the University of Innsbruck (University of Innsbruck) (submittedVersion, cc-by)
- Topics
- Physical Sciences › Chemistry › Analytical Chemistry › Spectroscopy and Chemometric Analyses
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
- Keywords
- near-infrared spectroscopy, natural medicine, medicinal plants, miniaturized spectrometer, bioactive compounds, quality control of herbal products
- MeSH terms
- Data Analysis, Biological Products, Reproducibility of Results, Spectroscopy, Near-Infrared
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