Cited by 397Diabetes Management and ResearchDiabetes Management and EducationDiabetes and associated disorders

Glycemic control in youth with diabetes: the SEARCH for Diabetes in Youth Study

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Petitti, Diana B., Klingensmith, Georgeanna J., Bell, Ronny A., Andrews, Jeanette S., Dabelea, Dana, Imperatore, Giuseppina, Marcovina, Santica, Pihoker, Catherine +3 more·2009·The Journal of Pediatrics

Abstract

Objective To assess correlates of glycemic control in a diverse population of children and youth with diabetes.Study design This was a cross-sectional analysis of data from a 6-center US study of diabetes in youth, including 3947 individuals with type 1 diabetes (T1D) and 552 with type 2 diabetes (T2D), using hemoglobin A(1c) (HbA(1c)) levels to assess glycemic control.Results HbA(1c) levels reflecting poor glycemic control (HbA(1c) >or= 9.5%) were found in 17% of youth with T1D and in 27% of those with T2D. African-American, American Indian, Hispanic, and Asian/Pacific Islander youth with T1D were significantly more likely to have higher HbA(1c) levels compared with non-Hispanic white youth (with respective rates for poor glycemic control of 36%, 52%, 27%, and 26% vs 12%). Similarly poor control in these 4 racial/ethnic groups was found in youth with T2D. Longer duration of diabetes was significantly associated with poorer glycemic control in youth with T1D and T2D.Conclusions The high percentage of US youth with HbA(1c) levels above the target value and with poor glycemic control indicates an urgent need for effective treatment strategies to improve metabolic status in youth with diabetes.

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Crossref · 10.1016/j.jpeds.2009.05.025

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  • Post-DCCT studies show mean A1c levels remained higher than current glycemic goals; the Hvidore study reported a mean A1c of 8.6% in over 2,000 youth with type 1 diabetes worldwide.

    “More recently, studies published post-DCCT have shown that mean levels of A1c have remained higher than current glycemic goals with the Hvidore study reporting a mean A1c of 8.6% in over 2,000 youth with T1D worldwide87.”

    From Epidemiology of type 1 diabetes (2010) · cites this paper as [87]

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References 41 · Cited by 397

Authors
Petitti, D. B., Klingensmith, G. J., Bell, R. A., Andrews, J. S., Dabelea, D., Imperatore, G., Marcovina, S., Pihoker, C., Standiford, D., Waitzfelder, B., & Mayer-Davis, E.
Affiliations
  • Arizona State University (US)
  • University of Colorado Denver (US)
  • Wake Forest University Health Sciences (US)
  • Colorado School of Public Health (US)
  • Centers for Disease Control and Prevention (US)
  • University of Washington (US)
  • Seattle Children's Hospital (US)
  • Cincinnati Children's Hospital Medical Center (US)
  • Pacific Health Research and Education Institute (US)
Corresponding author
Bell, Ronny A.
Venue
The Journal of Pediatrics
Publisher
Elsevier BV
Published
2009-11
Volume
155
Issue
5
Pages
668-672.e3
ISSN
0022-3476 (ISSN-L)
OpenAlex
W2142009487
Cited by
397
References
41
Citations by year
2026: 5 · 2025: 9 · 2024: 13 · 2023: 18 · 2022: 28 · 2021: 23 · 2020: 26 · 2019: 26 · 2018: 37 · 2017: 26 · 2016: 26 · 2015: 34 · 2014: 36 · 2013: 22 · 2012: 29
FWCI
15.97
Type
journal article
Language
en
Open access
Locations
  • The Journal of Pediatrics (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • Centers for Disease Control and Prevention (00097, DP-05-069)
  • National Institute of Diabetes and Digestive and Kidney Diseases
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
Keywords
glycemic control, youth with diabetes, type 1 diabetes, type 2 diabetes, HbA1c, racial and ethnic disparities, diabetes duration, SEARCH for Diabetes in Youth
MeSH terms
Adolescent, Analysis of Variance, Blood Glucose, Child, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Ethnicity, Female, Follow-Up Studies, Glycated Hemoglobin, Humans, Hypoglycemic Agents, Male, Probability, Registries, Severity of Illness Index, United States, Body Mass Index, Incidence, Multivariate Analysis, Linear Models, Risk Assessment, Diabetes Complications, Young Adult

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