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Cited by 70Mobile Health and mHealth ApplicationsCeliac Disease Research and ManagementDiabetes Management and Education

Text Message Intervention (TEACH) Improves Quality of Life and Patient Activation in Celiac Disease: A Randomized Clinical Trial

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Haas, Kelly, Martin, Andrew, Park, K.T.·2017·The Journal of Pediatrics
DOI 10.1016/j.jpeds.2017.02.062PMC PMC5637528
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Abstract

Objective To determine the impact of the Text Message Educational Automated Compliance Help (TEACH) text message intervention as a pragmatic approach for patient engagement among adolescents with celiac disease (CD) as measured by gluten-free diet (GFD) adherence, patient activation, and quality of life (QOL). Study design Randomized controlled trial with patient recruitment at a pediatric, university-based hospital and through social media; 61 participants ages 12-24 years with CD diagnosed at least 1 year were enrolled. The TEACH intervention cohort received 45 unique text messages over a 3-month study period while the control group received standard of care treatment. Primary outcome measures included objective markers of GFD adherence included serum tissue transglutaminase IgA and deamidated gliadin peptide IgA levels. Secondary patient-reported outcomes collected via online survey included the Celiac Dietary Adherence Test, National Institutes of Health (NIH) Patient-Reported Outcomes Measurement Information System (PROMIS) Global Short Form measure of QOL, Celiac Symptom Index, and Patient Activation Measure. All measures were assessed at enrollment and after the 3-month study period. Statistical analysis performed using the 2-tailed paired Student t test. Results Among the TEACH intervention group, there was significant improvement comparing enrollment scores with 3-month follow-up scores in patient activation (Patient Activation Measure score 63.1 vs 72.5, P?=?.01) and QOL (NIH PROMIS Global Mental Health 50.8 vs 53.3, P?=?.01 and NIH PROMIS Global Physical Health 50.8 vs 57.7, P?=?.03). There was no statistically significant difference in patient-reported or objectively measured GFD adherence. Conclusions TEACH is an effective intervention among patients with CD to improve patient activation and QOL, even among a cohort with GFD adherence at baseline. Trial registration ClinicalTrials.gov: NCT02458898.

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  • Both E-health interventions (Text Message intervention and online consultation) positively affected self-management, quality of life, patient satisfaction, and in one study reduced health-care costs compared with conventional in-office standard of care.

    “Both interventions positively affected selfmanagement, QoL, patient satisfaction, and in one study reduced health-care costs compared with conventional in-office standard of care.”

    From ESPGHAN Position Paper on Management and Follow-up of Children and Adolescents With Celiac Disease. (2022) · cites this paper as [17]

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  • Three studies, of which two were randomized clinical trials, have investigated E-health in the follow-up of patients with coeliac disease.

    “Three studies (of which two were RCTs (17,18) have investigated E-health in the follow-up of patients with CD.”

    From ESPGHAN Position Paper on Management and Follow-up of Children and Adolescents With Celiac Disease. (2022) · cites this paper as [17]

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Authors
Haas, K., Martin, A., & Park, K. T.
Affiliations
Stanford Medicine (US)
Corresponding author
Haas, Kelly
ORCID
Venue
The Journal of Pediatrics
Publisher
Elsevier BV
Published
2017-06
Volume
185
Pages
62-67.e2
ISSN
0022-3476 (ISSN-L)
DOI
10.1016/j.jpeds.2017.02.062
PMC
PMC5637528
OpenAlex
W2600487141
Cited by
70
References
41
Citations by year
2026: 3 · 2025: 4 · 2024: 8 · 2023: 8 · 2022: 9 · 2021: 10 · 2020: 15 · 2019: 6 · 2018: 3 · 2017: 3
FWCI
11.97
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The Journal of Pediatrics (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (UL1TR001085)
  • National Institute of Diabetes and Digestive and Kidney Diseases (K08DK094868, T32DK007056)
  • National Center for Research Resources (UL1RR025744)
  • National Center for Advancing Translational Sciences
Topics
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
  • Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Keywords
celiac disease, text messaging intervention, patient activation, quality of life, gluten-free diet adherence, adolescents, patient engagement, mobile health, patient-reported outcomes, anti-tissue transglutaminase IgA
MeSH terms
Protein Glutamine gamma Glutamyltransferase 2, Adolescent, Celiac Disease, Child, Female, Gliadin, Humans, Immunoglobulin A, Male, Patient Compliance, Patient Participation, Peptide Fragments, Transglutaminases, Quality of Life, GTP-Binding Proteins, Diet, Gluten-Free, Young Adult, Text Messaging

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