What have we learned about GPER function in physiology and disease from knockout mice

Prossnitz, Eric R., Hathaway, Helen J.·2015·The Journal of Steroid Biochemistry and Molecular Biology

Cited by (158)

Items 101–158 of 158

  1. Insulin receptor cleavage induced by estrogen impairs insulin signaling
    Tomoyuki Yuasa, Yasunori Takata, Nanako Aki, Kotaro Kunimi, Miki Satoh, Mari Nii, Yoshihiko Izumi, Toshiki Otoda, Seiichi Hashida, Haruhiko Osawa et al. · 2021 · BMJ Open Diabetes Research & Care
  2. The Importance of G-protein Coupled Estrogen Receptor in Patients With Fibromyalgia
    Tuba Tülay Koca, Burhan Fatih Koçyiğit, Muhammed Seyithanoğlu, Ejder BERK · 2019 · Archives of Rheumatology
  3. Sex differences in murine myocutaneous flap revascularization
    Jacquelyn S. Brandenburg, Ross M Clark, Brittany B. Coffman, Geetanjali Sharma, Helen J. Hathaway, Eric R. Prossnitz, Thomas R. Howdieshell · 2020 · Wound Repair and Regeneration
  4. Interaction of GPER-1 with the endocrine signaling axis in breast cancer
    Luis Molina, Yennyfer Arancibia, Marcela Alejandra Olivera, Sigrid Domke, Rodrigo Flavio Torres · 2025 · Frontiers in Endocrinology
  5. Gastric calcifying fibrous tumor: A clinicopathological study of nine cases
    Shan Tian, Zhi Rong Zeng, Xiulan Peng, Weiguo Dong · 2018 · Experimental and Therapeutic Medicine
  6. Association between Estradiol/Estrogen Receptors and Cognition: A Knowledge Domain Visualization Analysis of Trends
    Min Wu, Shujie Lou · 2023 · Medical Science Monitor
  7. The Role of Female Reproductive Hormones in the Association between Migraine and Breast Cancer: An Unanswered Question
    Paola Tiberio, Alessandro Viganò, Mariya Boyanova Ilieva, Sebastiano Pindilli, Anna Bianchi, Alberto Zambelli, Armando Santoro, Rita De Sanctis · 2023 · Biomedicines
  8. Mouse testicular transcriptome after modulation of non-canonical oestrogen receptor activity
    Michał Duliban, Artur Gurgul, Tomasz Szmatoła, Piotr Pawlicki, Agnieszka Milon, Zbigniew Arent, Paweł Grzmil, Małgorzata Kotula‐Balak, Barbara Bilińska · 2020 · Reproduction Fertility and Development
  9. Assessment of Metabolic Regulation by Estrogen Receptors
    Geetanjali Sharma, Eric R. Prossnitz · 2022 · Methods in molecular biology
  10. Tumour initiation, store-operated calcium entry (SOCE) and apoptosis: cyclic nucleotide dependence
    William R. Williams · 2020 · General Physiology and Biophysics
  11. Guest editorial: 11th international meeting on rapid responses to steroid hormones RRSH2018
    Brian Joseph Harvey · 2019 · Steroids
  12. The complex interaction between oestrogen receptor genes, oestradiol, and perinatal mood
    Gianna Zorzini, Alexandra Johann, Jelena Đukić, Ulrike Ehlert · 2025 · Dialogues in Clinical Neuroscience
  13. Mineralocorticoid and estrogen receptors as sex-dependent modulators of vascular health in aging and obesity
    Casey G. Turner, Karla de Oliveira, Iris Zamir Jaffe, Jennifer J. DuPont · 2025 · Journal of Pharmacology and Experimental Therapeutics
  14. Characterization of G protein‐coupled estrogen receptors in Japanese medaka, Oryzias latipes
    Kaori Miyaoku, Yukiko Ogino, Anke Lange, Ayaka Ono, Tohru Kobayashi, Masaru Ihara, Hiroaki Tanaka, Kenji Toyota, Hiroshi D. Akashi, Genki Yamagishi et al. · 2020 · Journal of Applied Toxicology
  15. Expression of steroidogenic enzymes and steroid receptors in foetal gonads of domestic cat—Sex similarities and differences
    BC Braun, Katarina Jewgenow · 2016 · Reproduction in Domestic Animals
  16. Immunolocalization of G Protein‐Coupled Estrogen Receptor in the Pig Epididymis
    Rocco Malivindi, Saveria Aquila, Vittoria Rago · 2018 · The Anatomical Record
  17. GPER deficiency impedes murine myocutaneous revascularization and wound healing
    Randy Ko, Oliver Q. C. Davidson, Michael A. Ahmed, Ross M Clark, Jacquelyn S. Brandenburg, V. Shane Pankratz, Geetanjali Sharma, Helen J. Hathaway, Eric R. Prossnitz, Thomas R. Howdieshell · 2024 · Scientific Reports
  18. G-protein couple receptor (GPER1) plays an important role during ovarian folliculogenesis and early development of the Chinese Alligator
    Yue Wen, Jixiang Zhan, Changcheng Li, Pengfei Li, Chong Wang, Jie Jayne Wu, Yunlu Xu, Yuqian Zhang, Yongkang Zhou, En Li et al. · 2023 · Animal Reproduction Science
  19. G-Protein-coupled Estrogen Receptor 1 (GPER1) Overexpression Affects Aggressiveness of Cervical Carcinoma Cells Depending on Histological Entity
    LENA HAMBACH, Julia K. S. Gallwas, Carsten Gründker · 2025 · Cancer Genomics & Proteomics
  20. Role for Nongenomic Estrogen Signaling in Male Fertility
    Jones Bernardes Graceli, Helena D. Zomer, Theresa I. Medrano, Rex A. Hess, Kenneth Steven Korach, Paul S. Cooke · 2023 · Endocrinology
  21. GPR30 Selective Agonist G1 Exhibits Antiobesity Effects and Promotes Insulin Resistance and Gluconeogenesis in Postmenopausal Mice Fed a High‐Fat Diet
    Da Liu, Mingqi Zheng, Congcong Lu, Mengdan Miao, Yinge Zhan, Fangfang Ma, Yajuan Yin, Mei Wei, Wei Wang, Wenyao Wang et al. · 2024 · Journal of Lipids
  22. Novel estrogen receptor-α gene inactivating missense variant in a woman: Therapeutic challenge and long-term follow-up data
    Eva Feigerlová · 2025 · Bone
  23. G protein-coupled estrogen receptor expression in postnatal developing mouse retina
    Wendy L. Piñon-Teal, Judith Mosinger Ogilvie · 2024 · Frontiers in Ophthalmology
  24. Therapeutic significance of long noncoding RNAs in estrogen receptor‐positive breast cancer
    Abdullah Ali Alzahrani, Raed Obaid Saleh, Amaliya latypova, Dmitry Olegovich Bokov, Anaheed Hussein Kareem, Hayder Abdullah Talib, Noora M. Hameed, Atreyi Pramanik, Ahmed Hussien Alawadi, Ali Alsalamy · 2024 · Cell Biochemistry and Function
  25. Estradiol 17-β Induces Pancreatic Beta-Cell Proliferation through Distinct Estrogen Receptors in a Glucose Dependent Manner
    Sigal Shaklai, Meital Grafi‐Cohen, Orli Sharon, Gabi Shefer, Dalia Sömjen, Naftali Stern · 2019 · OBM Transplantation
  26. Assessing Estrogenic Activity of Classical Estrogen Receptor-Binding Compounds
    Richard A. Pepermans, Eric R. Prossnitz · 2022 · Methods in molecular biology
  27. GPER1 reduces skin inflammation by inhibiting keratinocyte proliferation
    Natalia Pérez-Escudero, Isabel Cabas, Raúl Corbalán-Vélez, Teresa Martínez‐Menchón, Belén Ferri, María Luisa Cayuela, Diana García‐Moreno, Alfonsa Garcı́a Ayala, Víctoriano Mulero · 2026 · Cell Death Discovery
  28. Hormonal Dysregulation and Neuroinflammation in Endometriosis: Convergent Druggable Pathways
    Ioana-Laura Olteanu, Ciprian Pușcașu, Corina Andrei, Anca Zanfirescu · 2026 · Current Issues in Molecular Biology
  29. Endocrine, Reproductive, Neurophysiologic and Extraneous Activities of Estrogen in Vertebrates
    O N Nwankudu · 2021 · Nigerian Veterinary Journal
  30. G-Protein Coupled Hormone Receptors of the Hypothalamic-Pituitary-Gonadal Axis are Targets of Endocrine Disrupting Chemicals
    Valentine Suteau, Patrice Rodien, Mathilde Munier · 2021 · IntechOpen eBooks
  31. GPER expression prevents estrogen-induced urinary retention in obese mice
    Donna F. Kusewitt, Geetanjali Sharma, Christine D Woods, Emmanuel Rosas, Helen J. Hathaway, Eric R. Prossnitz · 2024 · The Journal of Steroid Biochemistry and Molecular Biology
  32. GPR30-mediated the MEK/ERK signaling pathway promotes porcine oocyte maturation and development
    Jiaxin Duan, Anli Xu, Junhao Xie, Linghao Wang, Qipin Lv, Jingxian Yang, Ning Zhao, Bugao Li, Guoqing Cao · 2025 · Theriogenology
  33. GPER a Potent Target of Xenoestrogens: An Overview on Biological Activity and Mechanism of Action in Cancer and Immunogenic Pathway
    Sumana Das, Sudipta Majumdar nee Paul · 2025 · Proceedings of the Zoological Society
  34. Estrogen Neuroprotection and Anti-Inflammation Actions in the Hippocampus
    Roshni Thakkar, Ruimin Wang, Gangadhara R. Sareddy, Ratna K. Vadlamudi, Darrell W. Brann · 2020 · Oxford University Press eBooks
  35. G protein-coupled estrogen receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
    Edward J. Filardo, Richard R. Neubig, Eric R. Prossnitz · 2019 · IUPHAR/BPS Guide to Pharmacology CITE
  36. Female Reproductive System
    Darlene Dixon, Alexander Yu. Nikitin, Joel F. Mahler · 2021
  37. The Effects of the Environmental Estrogens Cadmium and Arsenite on Phosphorylation of ERK1/2 via GPR30 in Human Lung Adenocarcinoma Cells
    Katarzyna Krauss · 2016
  38. The Use of Transcriptional Profiling in In Vitro Systems to Determine the Potential Estrogenic Activity of Chemicals of Interest
    Jorge M. Naciff · 2017 · Elsevier eBooks
  39. Induced ablation of skeletal muscle-specific estrogen receptor-alpha in adult female mice increased the susceptibility to develop skeletal muscle inflammation and glucose intolerance under chronic lipid overload
    Melissa Mae Raval Iñigo · 2018 · The Scholarship East Carolina University's Institutional Repository (East Carolina University)
  40. G protein-coupled estrogen receptor in GtoPdb v.2021.3
    Edward J. Filardo, Richard R. Neubig, Eric R. Prossnitz · 2021 · IUPHAR/BPS Guide to Pharmacology CITE
  41. Sex Hormone Receptor Signals in Human Malignancies
    Miyamoto, Hiroshi · 2019 · MDPI eBooks
  42. Faculty Opinions recommendation of A selective ligand for estrogen receptor proteins discriminates rapid and genomic signaling.
    M Madan Babu, Maria Marti · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  43. GPR30 negatively regulates inflammation in gout by inhibiting IL-1β production
    Hongyan Qian, Rongjuan Chen, Shiju Chen, Yan He, Yuan Liu, Guixiu Shi · 2020
  44. G protein-coupled estrogen receptor in GtoPdb v.2023.1
    Edward J. Filardo, Eric R. Prossnitz · 2023 · IUPHAR/BPS Guide to Pharmacology CITE
  45. RISCO ONCOLÓGICO NA TERAPIA HORMONAL DO CLIMATÉRIO: EVIDÊNCIAS ATUAIS E PROTOCOLOS DE SEGURANÇA
    Carolinne Domingues Pereira De Medeiros, João Luiz Vinhal Júnior, Thiago Motta Vaz Rodrigues, Giovanna Santos Barchet, Cecília Cerqueira Suzarte Almeida, Kamile Maria Saboia Moreira, Júlia Meschessi Vidigal Gouveia Teixeira, Bernardo Resende Lopes De Lacerda, Ana Clara Moreira Neves, Bernardo Morais Da Costa et al. · 2025 · LUMEN ET VIRTUS
  46. Development and Function of the Ovaries and Testes in the Fetus and Neonate
    Analia Veronica Freire, María Gabriela Ropelato, Rodolfo Alberto Rey · 2025 · Elsevier eBooks
  47. Additional file 1 of Growth characteristics of HCT116 xenografts lacking asparagine synthetase vary according to sex
    Oladimeji B. Aladelokun, Lu, Lingeng, Jie Zheng, Yan, Hong, Abhishek Jain, Gibson, Joanna, Khan, Sajid A., Caroline Helen Johnson · 2024 · Figshare
  48. Additional file 2 of Growth characteristics of HCT116 xenografts lacking asparagine synthetase vary according to sex
    Oladimeji B. Aladelokun, Lu, Lingeng, Jie Zheng, Yan, Hong, Abhishek Jain, Gibson, Joanna, Khan, Sajid A., Caroline Helen Johnson · 2024 · Figshare
  49. The implementation of small molecule agonists and antagonists to elucidate gonadotropin receptor structure, function and physiology
    James A. Dias, Claire L. Newton, Alfredo Ulloa‐Aguirre · 2026 · Molecular and Cellular Endocrinology
  50. Exploration de l’impact de l’exposition chronique et faibles doses de facteurs environnementaux sur les cellules pré-cancéreuses mammaires MCF10AT1
    Myriam El Helou · 2017
  51. Études des altérations cellulaires et moléculaires dans les tumeurs ovariennes des cellules de la granulosa
    Victoria Cluzet · 2021
  52. Activité endocrine de l'ovaire au cours de la mini-puberté : mécanismes sous-jacents et rôle dans la fonction de reproduction
    Marie M. Devillers · 2021
  53. La signalisation oestrogénique : effets dans le testicule et perturbation par le bisphénol A et les mycotoxines du genre Fusarium
    Maëva Drouault · 2022
  54. Antinociception and neuroprotection of the peptidic G protein‐coupled estrogen receptor inverse agonist PLMI in the murine model of paclitaxel‐induced peripheral neuropathy
    Baptiste Jouffre, Alexandre Acramel, Pascale Coric, Pauline Gousseau, Julie Barbier, Youssef Aissouni, Laurence Daulhac, Serge Bouaziz, Yves Jacquot, Christophe Mallet · 2026 · British Journal of Pharmacology
  55. More than alternative estrogen receptors: the emerging role of GPER-1 and ERα36 in breast cancer
    Luis Molina, Rodrigo Flavio Torres, Johana Spies, Sonia Sánchez Meneses, María Soto, Joaquín Carrasco, Javiera Gálvez, Dayanara Muñoz, Javiera Soto, Yennyfer Arancibia · 2026 · Exploration of Targeted Anti-tumor Therapy
  56. Sexual dimorphism in the liver
    Anisha Jain, Satdarshan P. Monga · 2026 · Nature Reviews Gastroenterology & Hepatology
  57. Evaluation of Serum G Protein-Coupled Estrogen Receptor-1 (GPER-1) Levels in Children With Cleft Palate: A Pilot Controlled Study
    Fatma Bilgen, E.B. Kurutas, Alper Ural, Mehmet Bekerecioğlu · 2026 · The Cleft Palate-Craniofacial Journal
  58. Sex differences in hepatitis A virus infection in mice
    Ichiro Misumi, Itoe Shiota, Tomoyuki Shiota, Jingyu Zhao, John Michael Cullen, Stanley M. Lemon, Jason K. Whitmire · 2026 · PLoS Pathogens