The Possible Damaged Mechanism and the Preventive Effect of Monosialotetrahexosylganglioside in a Rat Model of Cerebral Ischemia-Reperfusion Injury

Zhang, Jie; Fang, Xin; Zhou, Yiyi; Deng, Xia; Lu, Yi; Li, Jiao; Li, Shujuan; Wang, Bo; Xu, Renshi

doi:10.1016/j.jstrokecerebrovasdis.2015.02.008

The Possible Damaged Mechanism and the Preventive Effect of Monosialotetrahexosylganglioside in a Rat Model of Cerebral Ischemia-Reperfusion Injury

Background The pathogenesis of cerebral ischemia-reperfusion injury (CIRI) is not completely clear and therapies are limited now. Therefore, our study aimed to investigate the possible pathogenesis and preventive approach of CIRI through analyzing changes of aspartate (Asp), glutamate (Glu), mito…