Cited by 304Antiplatelet Therapy and Cardiovascular DiseasesCoronary Interventions and DiagnosticsAcute Myocardial Infarction Research

2016 ACC/AHA guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease

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Levine, Glenn N., Bates, Eric R., Bittl, John A., Brindis, Ralph G., Fihn, Stephan D., Fleisher, Lee A., Granger, Christopher B., Lange, Richard A. +25 more·2016·The Journal of Thoracic and Cardiovascular Surgery

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Crossref · 10.1016/j.jtcvs.2016.07.044

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  • Antiplatelet agents reduce cardiovascular events and mortality, but their wider use is limited by increased bleeding risk and nonadherence.

    “Use of antiplatelet agents has become a cornerstone for the treatment of CVD because of substantial reduction in CVD events and mortality37,38. However, more widespread use of antiplatelet agents has been limited by the increased risk of bleeding, which also leads to nonadherence39–41.”

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References 170 · Cited by 304

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Research works printed but not linked: 4

  1. Methodology and Evidence Review . . . . . . . . . . . 1247 1.
  2. Review and Approval . . . . . . . . . . . . . . . . . . . . . 1247
  3. Critical Questions and Systematic Review Findings . . 1247 2.1. Critical Questions on Duration of DAPT . . . . . . . . 1247 2.2. Studies of Shorter-Duration DAPT After Stent Implantation. . . . . . . . . . . . . . . . . . . . . . . . . . . . 1248 2.3. Studies of Longer-Duration DAPT After Stent Implantation. . . . . . . . . . . . . . . . . . . . . . . . . . . . 1248
  4. Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in pa- tients with acute coronary syndromes. N Engl J Med. 2009;361:1045-57.

Authors
Levine, G. N., Bates, E. R., Bittl, J. A., Brindis, R. G., Fihn, S. D., Fleisher, L. A., Granger, C. B., Lange, R. A., Mack, M. J., Mauri, L., Mehran, R., Mukherjee, D., Newby, L. K., O'Gara, P. T., Sabatine, M. S., Smith, P. K., Smith, S. C., Halperin, J. L., Levine, G. N., Al-Khatib, S. M., Birtcher, K. K., Bozkurt, B., Brindis, R. G., Cigarroa, J. E., Curtis, L. H., Fleisher, L. A., Gentile, F., Gidding, S., Hlatky, M. A., Ikonomidis, J. S., Joglar, J. A., Pressler, S. J., & Wijeysundera, D. N.
Affiliations
  • American Heart Association (US)
  • American College of Cardiology (US)
Venue
The Journal of Thoracic and Cardiovascular Surgery
Publisher
Elsevier BV
Published
2016-11
Volume
152
Issue
5
Pages
1243-1275
ISSN
0022-5223 (ISSN-L)
OpenAlex
W2530440392
Cited by
304
References
170
Citations by year
2026: 13 · 2025: 10 · 2024: 19 · 2023: 19 · 2022: 20 · 2021: 43 · 2020: 38 · 2019: 48 · 2018: 45 · 2017: 40 · 2016: 8 · 2015: 1
FWCI
38.71
Type
journal article
Language
en
Open access
Locations
  • Journal of Thoracic and Cardiovascular Surgery (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • American Heart Association
  • Office of Science
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Antiplatelet Therapy and Cardiovascular Diseases
  • Health Sciences › Medicine › Surgery › Coronary Interventions and Diagnostics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
Keywords
dual antiplatelet therapy, antiplatelet therapy duration, coronary artery disease, percutaneous coronary intervention, coronary artery bypass grafting, stable coronary artery disease, ST-elevation myocardial infarction, non-ST-elevation acute coronary syndrome, antiplatelet therapy discontinuation
MeSH terms
Algorithms, American Heart Association, Coronary Artery Disease, Humans, Platelet Aggregation Inhibitors, United States, Advisory Committees, Drug-Eluting Stents

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