2016 ACC/AHA guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease
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Antiplatelet agents reduce cardiovascular events and mortality, but their wider use is limited by increased bleeding risk and nonadherence.
“Use of antiplatelet agents has become a cornerstone for the treatment of CVD because of substantial reduction in CVD events and mortality37,38. However, more widespread use of antiplatelet agents has been limited by the increased risk of bleeding, which also leads to nonadherence39–41.”
From Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential (2018) · cites this paper as [38]
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References 170 · Cited by 304
Part of this paper’s reference list could not be split into single entries.
Research works printed but not linked: 4
- Methodology and Evidence Review . . . . . . . . . . . 1247 1.
- Review and Approval . . . . . . . . . . . . . . . . . . . . . 1247
- Critical Questions and Systematic Review Findings . . 1247 2.1. Critical Questions on Duration of DAPT . . . . . . . . 1247 2.2. Studies of Shorter-Duration DAPT After Stent Implantation. . . . . . . . . . . . . . . . . . . . . . . . . . . . 1248 2.3. Studies of Longer-Duration DAPT After Stent Implantation. . . . . . . . . . . . . . . . . . . . . . . . . . . . 1248
- Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in pa- tients with acute coronary syndromes. N Engl J Med. 2009;361:1045-57.
- Authors
- Levine, G. N., Bates, E. R., Bittl, J. A., Brindis, R. G., Fihn, S. D., Fleisher, L. A., Granger, C. B., Lange, R. A., Mack, M. J., Mauri, L., Mehran, R., Mukherjee, D., Newby, L. K., O'Gara, P. T., Sabatine, M. S., Smith, P. K., Smith, S. C., Halperin, J. L., Levine, G. N., Al-Khatib, S. M., Birtcher, K. K., Bozkurt, B., Brindis, R. G., Cigarroa, J. E., Curtis, L. H., Fleisher, L. A., Gentile, F., Gidding, S., Hlatky, M. A., Ikonomidis, J. S., Joglar, J. A., Pressler, S. J., & Wijeysundera, D. N.
- Affiliations
- American Heart Association (US)
- American College of Cardiology (US)
- ORCID
- Bates, Eric R.
- Bittl, John A.
- Granger, Christopher B.
- Lange, Richard A.
- Mack, Michael J.
- Mauri, Laura
- Mehran, Roxana
- Mukherjee, Debabrata
- Newby, L. Kristin
- Sabatine, Marc S.
- Halperin, Jonathan L.
- Birtcher, Kim K.
- Bozkurt, Biykem
- Cigarroa, Joaquin E.
- Curtis, Lesley H.
- Gentile, Federico
- Gidding, Samuel
- Hlatky, Mark A.
- Ikonomidis, John S.
- Joglar, José A.
- Pressler, Susan J.
- Wijeysundera, Duminda N.
- Venue
- The Journal of Thoracic and Cardiovascular Surgery
- Publisher
- Elsevier BV
- Published
- 2016-11
- Volume
- 152
- Issue
- 5
- Pages
- 1243-1275
- ISSN
- 0022-5223 (ISSN-L)
- OpenAlex
- W2530440392
- Cited by
- 304
- References
- 170
- Citations by year
- 2026: 13 · 2025: 10 · 2024: 19 · 2023: 19 · 2022: 20 · 2021: 43 · 2020: 38 · 2019: 48 · 2018: 45 · 2017: 40 · 2016: 8 · 2015: 1
- FWCI
- 38.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Thoracic and Cardiovascular Surgery (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Heart Association
- Office of Science
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Antiplatelet Therapy and Cardiovascular Diseases
- Health Sciences › Medicine › Surgery › Coronary Interventions and Diagnostics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
- Keywords
- dual antiplatelet therapy, antiplatelet therapy duration, coronary artery disease, percutaneous coronary intervention, coronary artery bypass grafting, stable coronary artery disease, ST-elevation myocardial infarction, non-ST-elevation acute coronary syndrome, antiplatelet therapy discontinuation
- MeSH terms
- Algorithms, American Heart Association, Coronary Artery Disease, Humans, Platelet Aggregation Inhibitors, United States, Advisory Committees, Drug-Eluting Stents
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