The Diversity of Gut Microbiome is Associated With Favorable Responses to Anti–Programmed Death 1 Immunotherapy in Chinese Patients With NSCLC

Jin, Yueping, Dong, Hui, Xia, Liliang, Yang, Yi, Zhu, Yongqiang, Shen, Yan, Zheng, Huajun, Yao, Chengcheng, Wang, Ying, Lu, Shun·2019·Journal of Thoracic Oncology

DOI 10.1016/j.jtho.2019.04.007

Cited by (570)

Items 101–200 of 570

The gut microbiota improves the efficacy of immune-checkpoint inhibitor immunotherapy against tumors: From association to cause and effect
Liliang Xia, Xiaokuan Zhu, Ying Wang, Shun Lü · 2024 · Cancer Letters
Predicting cancer immunotherapy response from gut microbiomes using machine learning models
Hai Liang, Jay‐Hyun Jo, Zhiwei Zhang, Margaret A. MacGibeny, Jungmin Han, Diana M. Proctor, Monica E. Taylor, You Che, Paul L. Juneau, Andrea Borghese Apolo et al. · 2022 · Oncotarget
Predictable Roles of Peripheral IgM Memory B Cells for the Responses to Anti-PD-1 Monotherapy Against Advanced Non-Small Cell Lung Cancer
Liliang Xia, Limin Guo, Jin U. Kang, Yi Yang, Yaxian Yao, Weimin Xia, Ruiming Sun, Shun Zhang, Wenfeng Li, Yu-Er Gao et al. · 2021 · Frontiers in Immunology
Solid tumour CAR-T cells engineered with fusion proteins targeting PD-L1 for localized IL-12 delivery
John Paul Murad, Lea Christian, Reginaldo Cruz Alves Rosa, Yuwei Ren, Alyssa J. Buckley, Eric Hee Jun Lee, Lupita S. Lopez, Anthony K. Park, Jason Yang, Yukiko Yamaguchi et al. · 2025 · Nature Biomedical Engineering
Gut microbiota as a biomarker and modulator of anti-tumor immunotherapy outcomes
Jiexi Yan, Lu Yang, Qingmiao Ren, Chan Zhu, Huimin Du, Zhouyu Wang, Yajuan Qi, Xiaohong Xian, Dongsheng Chen · 2024 · Frontiers in Immunology
Roles of the gut microbiota in immune-related adverse events: mechanisms and therapeutic intervention
Yaqi Gao, Yong-Jie Tan, Jing‐Yuan Fang · 2025 · Nature Reviews Clinical Oncology
Vaginal microbiota, genital inflammation, and neoplasia impact immune checkpoint protein profiles in the cervicovaginal microenvironment
Paweł Łaniewski, Haiyan Cui, Denise J. Roe, Dana M. Chase, Melissa M. Herbst‐Kralovetz · 2020 · npj Precision Oncology
Exploiting dietary fibre and the gut microbiota in pelvic radiotherapy patients
Selina E. Eaton, Justyna Kaczmarek, Daanish Mahmood, Anna M. McDiarmid, Alya N. Norarfan, Erin G. Scott, Chee Kin Then, Hailey Y. Tsui, Anne E. Kiltie · 2022 · British Journal of Cancer
The impact of the gut microbiome on tumor immunotherapy: from mechanism to application strategies
Ciliang Guo, Lingkai Kong, Lingjun Xiao, Kua Liu, Huawei Cui, Qilei Xin, Xiaosong Gu, Chunping Jiang, Junhua Wu · 2023 · Cell & Bioscience
Drug response in association with pharmacogenomics and pharmacomicrobiomics: towards a better personalized medicine
Radia Hassan, Imane Allali, Francis Edem Agamah, Samar S. M. Elsheikh, Nicholas Ekow Thomford, Collet Dandara, Emile Rugamika Chimusa · 2020 · Briefings in Bioinformatics
Analysis of the Gut Microbiota: An Emerging Source of Biomarkers for Immune Checkpoint Blockade Therapy in Non-Small Cell Lung Cancer
Feiyu Zhang, Macarena Ferrero, Ning Dong, Giuseppe D’Auria, Mariana Reyes‐Prieto, Alejandro Herreros‐Pomares, Silvia Calabuig Fariñas, Elena Duréndez-Saéz, Francisco Aparisi, Ana Blasco et al. · 2021 · Cancers
Faecal microbiota transplantation enhances efficacy of immune checkpoint inhibitors therapy against cancer
Yongbo Kang, Yue Cai · 2021 · World Journal of Gastroenterology
The Lung Microbiota and Lung Cancer: A Growing Relationship
Maroun Bou Zerdan, Joseph T. Kassab, Paul Meouchy, Elio Haroun, Rami Nehme, Morgan Bou Zerdan, Gracia Fahed, Michael Petrosino, Dibyendu Dutta, Stephen L. Graziano · 2022 · Cancers
Recognizing Prognostic and Predictive Biomarkers in the Treatment of Non-Small Cell Lung Cancer (NSCLC) with Immune Checkpoint Inhibitors (ICIs)
Nicholas Giustini, Lyudmila A. Bazhenova · 2021 · Lung Cancer Targets and Therapy
Mitochondria determine response to anti-programmed cell death protein-1 (anti-PD-1) immunotherapy: An evidence-based hypothesis
Hassan Akbari, Farzad Taghizadeh‐Hesary, Moslem Bahadori · 2021 · Mitochondrion
Immunotherapy for Metastatic Non-Small Cell Lung Cancer: Therapeutic Advances and Biomarkers
Marco Russano, Giulia La Cava, Alessio Cortellini, Fabrizio Citarella, Alessandro Galletti, Giuseppina Rita Di Fazio, Valentina Santo, Leonardo Brunetti, Alessia Vendittelli, Iacopo Fioroni et al. · 2023 · Current Oncology
A specific enterotype derived from gut microbiome of older individuals enables favorable responses to immune checkpoint blockade therapy
Xiaoqiang Zhu, Xiaowen Huang, Muni Hu, Rongrong Sun, Jiantao Li, Hai Wang, Xuefeng Pan, Yanru Ma, Lijun Ning, Tianying Tong et al. · 2024 · Cell Host & Microbe
Facts and Hopes for Gut Microbiota Interventions in Cancer Immunotherapy
Davar, Diwakar, Zarour, Hassane M. · 2022 · Clinical Cancer Research
Gut microbiota and its metabolites in non-small cell lung cancer and brain metastasis: from alteration to potential microbial markers and drug targets
Haixiao Jiang, Wei Gen Zeng, Xiaoli Zhang, Yuping Li, Yilun Wang, Aijun Peng, Demao Cao · 2024 · Frontiers in Cellular and Infection Microbiology
Gut microbiota diversity and specific composition during immunotherapy in responders with non-small cell lung cancer
Fumihiro Shoji, Masafumi Yamaguchi, Masaki Okamoto, Shinkichi Takamori, Koji Yamazaki, Tatsuro Okamoto, Yoshihiko Maehara · 2022 · Frontiers in Molecular Biosciences
Compartmentalization of the host microbiome: how tumor microbiota shapes checkpoint immunotherapy outcome and offers therapeutic prospects
Maximilian Boesch, Lena Horvath, Florent Baty, Andreas Pircher, Dominik Georg Friedrich Wolf, Stephan Spahn, Ravid Straussman, Herbert Tilg, Martin Hugo Brutsche · 2022 · Journal for ImmunoTherapy of Cancer
Metabolic Implications of Immune Checkpoint Proteins in Cancer
Elizabeth R. Stirling, Steven M. Bronson, Jessica D. Mackert, Katherine Loree Cook, Pierre L. Triozzi, David R. Soto‐Pantoja · 2022 · Cells
Alistipes finegoldii augments the efficacy of immunotherapy against solid tumors
Zhi‐Ying Wu, Qiwen Wu, Yi Han, Shu-Jing Xiang, Yingnan Wang, Wen-Wei Wu, Yan‐Xing Chen, Ziqing Feng, Yi-Yu Wang, Ze-Gong Xu et al. · 2025 · Cancer Cell
The Role of Gut Microbiota in Tumor Immunotherapy
Miao Wu, Jiawei Bai, Chengtai Ma, Jie Wei, Xianjin Du · 2021 · Journal of Immunology Research
Role and impact of immune checkpoint inhibitors in neoadjuvant treatment for NSCLC
Alex Friedlaender, Jarushka Naidoo, Giuseppe Luigi Banna, Giulio Metro, Patrick M. Forde, Alfredo Addeo · 2022 · Cancer Treatment Reviews
Infections and Immunotherapy in Lung Cancer: A Bad Relationship?
Lorenzo Belluomini, Alberto Caldart, Alice Avancini, Alessandra Dodi, Ilaria Trestini, Dzenete Kadrija, Marco Sposito, Daniela Tregnago, Miriam Casali, Silvia Teresa Riva et al. · 2020 · International Journal of Molecular Sciences
Prognostic and Predictive Biomarkers in the Era of Immunotherapy for Lung Cancer
Lucile Pabst, Sébastien Lopes, Basil Bertrand, Quentin Creusot, Maria Kotovskaya, Erwan Pencreach, Michèle Beau‐Faller, Céline Mascaux · 2023 · International Journal of Molecular Sciences
Gut microbiota and metabolites signatures of clinical response in anti-PD-1/PD-L1 based immunotherapy of biliary tract cancer
Chengpei Zhu, Yunchao Wang, Ruijuan Zhu, Shanshan Wang, Jingnan Xue, Dongya Zhang, Zhou Lan, Chenchen Zhang, Yajun Liang, Nan Zhang et al. · 2024 · Biomarker Research
Targeting gut-microbiota for gastric cancer treatment: a systematic review
Amir H. Marashi, Saina Hasany, Sadra Moghimi, Reza Kiani, Sina Mehran Asl, Yasamin Alavi Dareghlou, Parsa Lorestani, Shirin Varmazyar, Fatemeh Jafari, Shakiba Ataeian et al. · 2024 · Frontiers in Medicine
The crosstalk between the gut microbiota and tumor immunity: Implications for cancer progression and treatment outcomes
Man Wang, Lei Zhang, Wenguang Chang, Yuan Zhang · 2023 · Frontiers in Immunology
Effectiveness of PD-1/PD-L1 inhibitors in the treatment of lung cancer: Brightness and challenge
Ying Yang, Yongfeng Yu, Shun Lü · 2020 · Science China Life Sciences
The impact of antibiotics on efficacy of immune checkpoint inhibitors in malignancies: A study based on 44 cohorts
Qing Wu, Junjin Liu, Su‐Mei Wu, Xianhe Xie · 2021 · International Immunopharmacology
Unveiling the intratumoral microbiota within cancer landscapes
Shusheng Che, Zhiyong Yan, Yugong Feng, Zhao Hai · 2024 · iScience
Gut microbiota in acute leukemia: Current evidence and future directions
Yao Zhou, Chendan Zhou, Aijun Zhang · 2022 · Frontiers in Microbiology
Multi-omics of the gut microbial ecosystem in patients with microsatellite-instability-high gastrointestinal cancer resistant to immunotherapy
Siyuan Cheng, Zihan Han, Die Dai, Fang Li, Xiaotian Zhang, Ming Shian Lu, Zhihao Lü, Xicheng Wang, Jun Zhou, Jian Li et al. · 2024 · Cell Reports Medicine
An Exploratory Study for the Association of Gut Microbiome with Efficacy of Immune Checkpoint Inhibitor in Patients with Hepatocellular Carcinoma
Shen, Ying-Chun, Lee, Pei-Chang, Kuo, Yu-Lun, Wu, Wei-Kai, Chen, Chieh-Chang, Lei, Chengh-Hau, Yeh, Ching-Ping, Hsu, Chiun, Hsu, Chih-Hung, Lin, Zhong-Zhe et al. · 2021 · Journal of Hepatocellular Carcinoma
Resistance to immune checkpoint inhibitors in gastric cancer
Kai Liu, Shiman Yuan, Chenyu Wang, Hong Zhu · 2023 · Frontiers in Pharmacology
Serum Metabolite Biomarkers Predictive of Response to PD-1 Blockade Therapy in Non-Small Cell Lung Cancer
Xiaoqun Nie, Liliang Xia, Fang Gao, Lixia Liu, Yi Yang, Yingying Chen, Huangqi Duan, Yaxian Yao, Zhiwei Chen, Shun Lü et al. · 2021 · Frontiers in Molecular Biosciences
Nurturing and modulating gut microbiota with jujube powder to enhance anti-PD-L1 efficiency against murine colon cancer
Luoyang Wang, Nan Jing, Xuerun Liu, Guoqiang Jiang, Zheng Liu · 2019 · Journal of Functional Foods
Predictive Biomarkers for Immune-Checkpoint Inhibitor Treatment Response in Patients with Hepatocellular Carcinoma
Jun Ho Ji, Sang Yun Ha, Danbi Lee, K. Nathan Sankar, Ekaterina K. Koltsova, Ghassan K. Abou‐Alfa, Ju Dong Yang · 2023 · International Journal of Molecular Sciences
The Effect of Microbiome-Derived Metabolites in Inflammation-Related Cancer Prevention and Treatment
Alice Njolke Mafe, Dietrich Büsselberg · 2025 · Biomolecules
Distinct Functional Metagenomic Markers Predict the Responsiveness to Anti-PD-1 Therapy in Chinese Non-Small Cell Lung Cancer Patients
Chao Fang, Wenfeng Fang, Liqin Xu, Fangfang Gao, Yong Hou, Hua Zou, Yuxiang Ma, Janne Marie Moll, Yunpeng Yang, Dan Wang et al. · 2022 · Frontiers in Oncology
Management of Immune Checkpoint Inhibitor Toxicities
Quentin Durrechou, Charlotte Domblides, Baptiste Sionneau, Félix Lefort, Amandine Quivy, Alain Ravaud, Marine Gross‐Goupil, Amaury Daste · 2020 · Cancer Management and Research
The emerging role of the lung microbiome and its importance in non-small cell lung cancer diagnosis and treatment
Anna E. B. McLean, Steven Chuan-Hao Kao, David John Barnes, KEITH K. H. WONG, Richard A. Scolyer, Wendy A. Cooper, Maija R.J. Kohonen‐Corish · 2022 · Lung Cancer
Identification and Application of Emerging Biomarkers in Treatment of Non-Small-Cell Lung Cancer: Systematic Review
Juan Carlos Restrepo, Darly Martínez Guevara, Andrés Pareja López, John Fernando Montenegro Palacios, Yamil Liscano · 2024 · Cancers
Immune Checkpoint Inhibitors in Triple Negative Breast Cancer: The Search for the Optimal Biomarker
Sadaf Qureshi, Nancy Chan, Mridula Annette George, Shridar Ganesan, Deborah Toppmeyer, Coral Oghenerukevwe Omene · 2022 · Biomarker Insights
Current and future biomarkers for outcomes with immunotherapy in non-small cell lung cancer
Boris Duchemann, Jordi Remón, Marie Naigeon, Lydie Cassard, Jean-Mehdi Jouniaux, Lisa Boselli, Jonathan Grivel, Édouard Auclin, Aude Desnoyer, Benjamin Besse et al. · 2021 · Translational Lung Cancer Research
The Gut Microbiome and Gastrointestinal Toxicities in Pelvic Radiation Therapy: A Clinical Review
Byeongsang Oh, Thomas Eade, Gillian Lamoury, Susan L. Carroll, Marita Morgia, Andrew B. Kneebone, George Hruby, Mark John Stevens, Frances M. Boyle, Stephen John Clarke et al. · 2021 · Cancers
The commensal consortium of the gut microbiome is associated with favorable responses to anti-programmed death protein 1 (PD-1) therapy in thoracic neoplasms
Huihui Yin, Lu Yang, Gongxin Peng, Ke Yang, Yuling Mi, Xingsheng Hu, Xuezhi Hao, Yuchen Jiao, Xiaobing Wang, Yan Wang · 2021 · Cancer Biology and Medicine
Intestinal microbiota: A potential target for enhancing the antitumor efficacy and reducing the toxicity of immune checkpoint inhibitors
Baohua Luo, Yongbin Zhang, Caiqin Zhang, Xiaoqiu Liu, Changhong Shi · 2021 · Cancer Letters
Optimizing Cancer Treatment Through Gut Microbiome Modulation
Kyuri Kim, Mingyu Lee, Yoojin Shin, Yoonji Lee, Tae Jung Kim · 2025 · Cancers
Gut microbiota interactions with antitumor immunity in colorectal cancer: From understanding to application
Yu-Pei Zhuang, Hongli Zhou, Haibin Chen, Ming-Yue Zheng, Yuwei Liang, Yu-Tian Gu, Wenting Li, Wenli Qiu, Hongguang Zhou · 2023 · Biomedicine & Pharmacotherapy
Emerging role of microbiota in immunomodulation and cancer immunotherapy
Raghwendra Pratap Singh, Hilal Bashir, Rashmi Kumar · 2020 · Seminars in Cancer Biology
Stool Microbiome Signature Associated with Response to Neoadjuvant Pembrolizumab in Patients with Muscle-invasive Bladder Cancer
Pederzoli, Filippo, Riba, Michela, Venegoni, Chiara, Marandino, Laura, Bandini, Marco, Alchera, Elisa, Locatelli, Irene, Raggi, Daniele, Giannatempo, Patrizia, Provero, Paolo et al. · 2024 · European Urology
Emerging roles of the gut microbiota in cancer immunotherapy
Zhuangzhuang Shi, Hongwen Li, Wenting Song, Zhi‐Yuan Zhou, Zhaoming Li, Mingzhi Zhang · 2023 · Frontiers in Immunology
A Clinical Outcome of the Anti-PD-1 Therapy of Melanoma in Polish Patients Is Mediated by Population-Specific Gut Microbiome Composition
Pietrzak, Bernadeta, Tomela, Katarzyna, Olejnik-Schmidt, Agnieszka, Galus, Łukasz, Mackiewicz, Jacek, Kaczmarek, Mariusz, Mackiewicz, Andrzej, Schmidt, Marcin · 2022 · Cancers
Exploring the food-gut axis in immunotherapy response of cancer patients
Edda Russo, Giulia Nannini, Monica Dinu, Giuditta Pagliai, Francesco Sofi, Amedeo Amedei · 2020 · World Journal of Gastroenterology
Gut microbiota: A double-edged sword in immune checkpoint blockade immunotherapy against tumors
Juanjuan Wang, Ningning Zhu, Lei Su, Rongcun Yang · 2023 · Cancer Letters
Acarbose enhances the efficacy of immunotherapy against solid tumours by modulating the gut microbiota
Shilong Zhang, Xin Wang, Qing-Qing Cai, Chen Chen, Zheng-Yan Zhang, Yayun Xu, Mengxuan Yang, Qing-An Jia, Yan Wang, Zhi-ming Wang · 2024 · Nature Metabolism
Prognostic and Predictive Biomarkers in Non-Small Cell Lung Cancer Patients on Immunotherapy—The Role of Liquid Biopsy in Unraveling the Puzzle
Elien Augustus, Karen Zwaenepoel, Vasiliki Siozopoulou, Jo Raskin, Stephanie Jordaens, Geert Baggerman, Laure Sorber, Geert Roeyen, Marc Peeters, Patrick Pauwels · 2021 · Cancers
From bench to bedside: an interdisciplinary journey through the gut-lung axis with insights into lung cancer and immunotherapy
Dávid Dóra, Emőke Szőcs, Ádám Soós, Viktória Halasy, Csenge Somodi, Anna Mihucz, Melinda Rostás, Fruzsina Mógor, Zoltán Lohinai, Nándor Nagy · 2024 · Frontiers in Immunology
Peripheral CD4+ T cell signatures in predicting the responses to anti-PD-1/PD-L1 monotherapy for Chinese advanced non-small cell lung cancer
Liliang Xia, Hui Wang, Mingjiao Sun, Yi Yang, Chengcheng Yao, Sheng He, Huangqi Duan, Weimin Xia, Ruiming Sun, Yaxian Yao et al. · 2021 · Science China Life Sciences
Effects of Concomitant Antibiotics Use on Immune Checkpoint Inhibitor Efficacy in Cancer Patients
Shuai Jiang, Shuai Geng, Qian Chen, Chen Zhang, Mengfei Cheng, Yang Yu, Shuo Zhang, Ning Shi, Mei Dong · 2022 · Frontiers in Oncology
Anti-inflammatory Effects of Bacteroidota Strains Derived From Outstanding Donors of Fecal Microbiota Transplantation for the Treatment of Ulcerative Colitis
Dai Ishikawa, Xiaochen Zhang, Kei Nomura, Tomoyoshi Shibuya, Mariko Hojo, Makoto Yamashita, Satoshi Koizumi, Fuhito Yamazaki, Susumu Iwamoto, Masato Saito et al. · 2024 · Inflammatory Bowel Diseases
Exploiting the obesity-associated immune microenvironment for cancer therapeutics
Lysanne Desharnais, Logan A. Walsh, Daniela F. Quail · 2021 · Pharmacology & Therapeutics
Concomitant Proton Pump Inhibitor Use With Pembrolizumab Monotherapy vs Immune Checkpoint Inhibitor Plus Chemotherapy in Patients With Non−Small Cell Lung Cancer
Hayato Kawachi, Tadaaki Yamada, Motohiro Tamiya, Yoshiki Negi, Yasuhiro Gotô, Akira Nakao, Shinsuke Shiotsu, Keiko Tanimura, Takayuki Takeda, Asuka Okada et al. · 2023 · JAMA Network Open
Baseline gut microbiota composition is associated with oral mucositis and tumour recurrence in patients with head and neck cancer: a pilot study
Ghanyah H. Al-Qadami, Joanne M. Bowen, Ysabella Z. A. Van Sebille, Kate R. Secombe, Mohsen Dorraki, Johan W. H. Verjans, Hannah R. Wardill, Hien V. Le · 2023 · Supportive Care in Cancer
Microbiota and Lung Cancer. Opportunities and Challenges for Improving Immunotherapy Efficacy
Maitane Ocáriz, Mara Cruellas, Marta Gascón Ruiz, Rodrigo Pimienta Lastra, Luis Martínez‐Lostao, Ariel Ramírez-Labrada, José Ramón Paño, Andrea Sesma, Irene Torres, Alfonso Yubero et al. · 2020 · Frontiers in Oncology
Impact of intestinal dysbiosis on breast cancer metastasis and progression
Jin Zhang, Qiqi Xie, Xingfa Huo, Zhilin Liu, Mengting Da, Mingxue Yuan, Yi D. Zhao, Guoshuang Shen · 2022 · Frontiers in Oncology
Mechanistic insight of predictive biomarkers for antitumor PD‑1/PD‑L1 blockade: A paradigm shift towards immunome evaluation (Review)
Wenjie You, Bin Shang, Jian Sun, Xueqing Liu, Lili Su, Shujuan Jiang · 2020 · Oncology Reports
Gut microbiota influences the efficiency of immune checkpoint inhibitors by modulating the immune system (Review)
Haihong Jiang, Qinlu Zhang · 2024 · Oncology Letters
Microbiota as the unifying factor behind the hallmarks of cancer
Iva Benešová, Ľudmila Křížová, Miloslav Kverka · 2023 · Journal of Cancer Research and Clinical Oncology
Attempting to Identify Bacterial Allies in Immunotherapy of NSCLC Patients
Anna Grenda, Ewelina Iwan, Paweł Adam Krawczyk, Małgorzata Frąk, Izabela Chmielewska, Arkadiusz Bomba, Aleksandra Giza, Anna Rolska-Kopińska, Michał Szczyrek, Robert Kieszko et al. · 2022 · Cancers
Novel insights on gut microbiota manipulation and immune checkpoint inhibition in cancer (Review)
Silvia Vivarelli, Luca Falzone, Giulia Costanza Leonardi, Mario Salmeri, Massimo Libra · 2021 · International Journal of Oncology
Distinct tumor bacterial microbiome in lung adenocarcinomas manifested as radiological subsolid nodules
Yi Ma, Mantang Qiu, Shaodong Wang, Shushi Meng, Fan Yang, Guanchao Jiang · 2021 · Translational Oncology
Role of the Microbiome and Diet for Response to Cancer Checkpoint Immunotherapy: A Narrative Review of Clinical Trials
Gamrath, Lone, Pedersen, Tobias Bruun, Møller, Martin Vad, Volmer, Lone Marie, Holst-Christensen, Linda, Vestermark, Lene Weber, Donskov, Frede · 2025 · Current Oncology Reports
Gut microbiota and dietary intervention: affecting immunotherapy efficacy in non–small cell lung cancer
Yu Xin, Chenguang Liu, Dan Zang, Jun Chen · 2024 · Frontiers in Immunology
Tumor Microbiome in Nasopharyngeal Carcinoma and Its Association With Prognosis
Guihua Zhong, Wei Wei, Wei Liao, Rong Wang, Yingpeng Peng, Yuling Zhou, Xiaotao Huang, Shiping Xian, Shunli Peng, Zhaoyuan Zhang et al. · 2022 · Frontiers in Oncology
Checkpoint inhibitor responses can be regulated by the gut microbiota – A systematic review
M. Zeriouh, Hans Raskov, Lasse Kvich, Ismail Gögenür, Astrid Louise Bjørn Bennedsen · 2023 · Neoplasia
Gut–lung axis: role of the gut microbiota in non-small cell lung cancer immunotherapy
Huaiyuan Zhang, Ziyuan Xu · 2023 · Frontiers in Oncology
Safety and Preliminary Efficacy of Pembrolizumab Following Transarterial Chemoembolization for Hepatocellular Carcinoma: The PETAL Phase Ib Study
David James Pinato, Antonio D’Alessio, Claudia Angela Maria Fulgenzi, Alexandra Emilia Schlaak, Ciro Celsa, Saskia Killmer, Jesús Miguéns Blanco, Caroline E. Ward, Charalampos‐Vlasios Stikas, Mark Robert Openshaw et al. · 2024 · Clinical Cancer Research
Polysaccharides of Sporoderm-Broken Spore of Ganoderma lucidum Modulate Adaptive Immune Function via Gut Microbiota Regulation
Lu Su, Dan Li, Jiyan Su, Enqi Zhang, Shaodan Chen, Zheng Chaoqun, Ting L. Luo, Muxia Li, Xiaohong Chen, Guoxin Huang et al. · 2021 · Evidence-based Complementary and Alternative Medicine
Influence of gut and lung dysbiosis on lung cancer progression and their modulation as promising therapeutic targets: a comprehensive review
Rajan Thapa, Anjana Thapa Magar, Jesus Shrestha, Nisha Panth, Sobia Idrees, Tayyaba Sadaf, Saroj Bashyal, Bassma Hassan Elwakil, Vrashabh V. Sugandhi, Satish V. Rojekar et al. · 2024 · MedComm
Cancer Immunotherapy with Immune Checkpoint Inhibitors-Biomarkers of Response and Toxicity; Current Limitations and Future Promise
Brian Bird, Kenneth Nally, Karine E. Ronan, Gerard A. Clarke, Sylvie Amu, Ana Santos Almeida, Richard Flavin, Stephen P. Finn · 2022 · Diagnostics
Gut microbial signature in lung cancer patients highlights specific taxa as predictors for durable clinical benefit
Yael Haberman, Iris Kamer, Amnon Amir, Sapir Goldenberg, Gilat Efroni, Inbal Daniel‐Meshulam, Anastasiya Lobachov, Sameh Daher, Rotem Hadar, Hadas Gantz-Sorotsky et al. · 2023 · Scientific Reports
Cancer immunotherapy resistance: The impact of microbiome-derived short-chain fatty acids and other emerging metabolites
Fatema Hersi, Sara M. Elgendy, Salma A. Al Shamma, Roa T. Altell, Omar Sadiek, Hany A. Omar · 2022 · Life Sciences
Atypical immunometabolism and metabolic reprogramming in liver cancer: Deciphering the role of gut microbiome
Rachel M. Golonka, Matam Vijay–Kumar · 2020 · Advances in cancer research
Relationship Between Adverse Events and Microbiomes in Advanced Hepatocellular Carcinoma Patients Treated With Sorafenib
Kenta Yamamoto, Teiji Kuzuya, Takashi Honda, Takanori Ito, Yoji Ishizu, Masanao Nakamura, Ryoji Miyahara, Hiroki Kawashima, Masatoshi Ishigami, Mitsuhiro Fujishiro · 2020 · Anticancer Research
Influence of Microbiota on Tumor Immunotherapy
Xin Yu, Wenge Li, Zhi Li, Qi Wu, Shengrong Sun · 2024 · International Journal of Biological Sciences
Microbiota Regulates Pancreatic Cancer Carcinogenesis through Altered Immune Response
Yihan Chai, Zhengze Huang, Xuqiu Shen, Tianyu Lin, Yiyin Zhang, Feng Xu, Qijiang Mao, Yuelong Liang · 2023 · Microorganisms
Inflammation Mediated by Gut Microbiome Alterations Promotes Lung Cancer Development and an Immunosuppressed Tumor Microenvironment
Zahraa Rahal, Yuejiang Liu, Fuduan Peng, Sujuan Yang, Mohamed A. Jamal, Manvi Sharma, Hannah Moreno, Ashish V. Damania, Matthew C. Wong, Matthew Clayton Ross et al. · 2024 · Cancer Immunology Research
The gut microbiome, immune check point inhibition and immune-related adverse events in non-small cell lung cancer
Philip Bredin, Jarushka Naidoo · 2022 · Cancer and Metastasis Reviews
The Species of Gut Bacteria Associated with Antitumor Immunity in Cancer Therapy
Xiaoqiang Qi, Yajun Liu, Samira Hussein, Grace Choi, Eric T. Kimchi, Kevin F. Staveley-O’Carroll, Guangfu Li · 2022 · Cells
The Gut Microbiome from a Biomarker to a Novel Therapeutic Strategy for Immunotherapy Response in Patients with Lung Cancer
Sreya Duttagupta, Taiki Hakozaki, Bertrand Routy, Meriem Messaoudene · 2023 · Current Oncology
Microbiome meets immunotherapy: unlocking the hidden predictors of immune checkpoint inhibitors
Huang, Lihaoyun, Li, Yu, Zhang, Chunyan, Jiang, Aimin, Zhu, Lingxuan, Mou, Weiming, Li, Kailai, Zhang, Jian, Cui, Cui, Cui, Xinfang et al. · 2025 · npj Biofilms and Microbiomes
Monitoring and Modulating Diet and Gut Microbes to Enhance Response and Reduce Toxicity to Cancer Treatment
Anne T. Knisely, Yongwoo David Seo, Jennifer Ann Wargo, Manoj Chelvanambi · 2023 · Cancers
A narrative review from gut to lungs: non-small cell lung cancer and the gastrointestinal microbiome
Hely Shah, Terry L. Ng · 2023 · Translational Lung Cancer Research
Microbial mechanisms to improve immune checkpoint blockade responsiveness
Matthew E. Griffin, Howard C. Hang · 2022 · Neoplasia
Xuanfei Baidu decoction ameliorates bleomycin-elicited idiopathic pulmonary fibrosis in mice by regulating the lung-gut crosstalk via IFNγ/STAT1/STAT3 axis
Mengjie Jia, Yiman Liu, Jia Liu, Junyu Meng, Jiazhen Cao, Lin Miao, Han Zhang, Yan Zhu, Mengmeng Sun, Jian Yang · 2024 · Phytomedicine
Immune Checkpoint Inhibitors: Review of the Existing Evidence and Challenges in Breast Cancer
Mobina Jalalvand, Farzaneh Darbeheshti, Nima Rezaei · 2021 · Immunotherapy