Erectile Function Outcome Reporting After Clinically Localized Prostate Cancer Treatment
Abstract
Purpose In conjunction with the assignment to update the Guidelines for Management of Clinically Localized Prostate Cancer, the American Urological Association Prostate Cancer Guideline Update Panel performed a side analysis of the reporting of erectile function outcomes in this clinical context as published in the medical literature. Materials and methods Four National Library of Medicine PubMed(R) Services literature searches targeting articles published from 1991 through early 2004 were done to derive outcome reporting (efficacy or side effects) for the treatment of clinical stage T1 or T2 N0M0 prostate cancer. A database was constructed containing descriptions relating to erectile function as well as numerical frequency rates of complete erectile dysfunction, and partial and intact erectile function for various treatments. A literature review was also done, consisting of a PubMed Services search of current measures and protocols used for assessing erectile function outcomes and a survey of consensus opinion sources on the management of male sexual dysfunctions. Results Based on inclusion criteria 436 articles were selected. Of these articles database extraction from 100 pertaining to radical prostatectomy garnered various characterizations of erectile function, including qualitative descriptions, generic terminology and rating systems. Database extraction from 31 articles, in which results for at least 50 patients were reported, yielded ranges of rates for complete erecti…
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Up to 90% of men treated for prostate cancer will experience significant sexual side effects.
“However, despite advances in the effectiveness of PC treatment in eradicating cancer, up to 90% of men treated will experience significant sexual side effects.1,3”
From Preliminary Development of a Mindfulness-Based Group Therapy to Expand Couples’ Sexual Intimacy after Prostate Cancer: A Mixed Methods Approach (2021) · cites this paper as [3]
Side effects of prostate cancer treatments impact the sexual lives of men and their partners, including erectile dysfunction, climacturia, anorgasmia, urinary or fecal incontinence, penile shortening, and/or loss of sexual desire.
“Side effects of PC treatments impact the sexual lives of men and their partners, including erectile dysfunction, climacturia (loss of urine with ejaculation), anorgasmia (inability to reach orgasm), urinary or fecal incontinence, penile shortening, and/or loss of sexual desire.1,3, 4, 5, 6,8,12”
From Preliminary Development of a Mindfulness-Based Group Therapy to Expand Couples’ Sexual Intimacy after Prostate Cancer: A Mixed Methods Approach (2021) · cites this paper as [3]
By focusing on changing or improving a prostate cancer survivor's erections, distress may be maintained or even worsened when his erections do not recover to pretreatment levels (which is the case in approximately 90% of men).
“By focusing on changing or improving a PC survivor’s erections, distress may be maintained or even worsened when his erections do not recover to pretreatment levels (which is the case in approximately 90% of men3).”
From Preliminary Development of a Mindfulness-Based Group Therapy to Expand Couples’ Sexual Intimacy after Prostate Cancer: A Mixed Methods Approach (2021) · cites this paper as [3]
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References 23 · Cited by 213
- Authors
- Burnett, A. L., Aus, G., Canby-Hagino, E. D., Cookson, M. S., D’Amico, A. V., Dmochowski, R. R., Eton, D. T., Forman, J. D., Goldenberg, S. L., Hernandez, J., Higano, C. S., Kraus, S., Liebert, M., Moul, J. W., Tangen, C., Thrasher, J. B., Thompson, I., & American Urological Association Prostate Cancer Guideline Update Panel
- Affiliations
- Johns Hopkins University (US)
- ORCID
- Venue
- Journal of Urology
- Published
- 2007-08
- Volume
- 178
- Issue
- 2
- Pages
- 597-601
- ISSN
- 0022-5347 (ISSN-L)
- 1527-3792
- OpenAlex
- W1974324227
- Cited by
- 213
- References
- 23
- Citations by year
- 2026: 1 · 2024: 4 · 2023: 5 · 2022: 5 · 2021: 5 · 2020: 9 · 2019: 11 · 2018: 8 · 2017: 9 · 2016: 7 · 2015: 14 · 2014: 11 · 2013: 10 · 2012: 15
- FWCI
- 15.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Urology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Prostate Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
- Keywords
- erectile function, erectile dysfunction, localized prostate cancer, radical prostatectomy, external beam radiotherapy, interstitial brachytherapy, outcome reporting, outcome measures, male sexual dysfunction, treatment side effects
- MeSH terms
- Brachytherapy, Humans, Erectile Dysfunction, Male, Neoplasm Staging, Outcome and Process Assessment, Health Care, Postoperative Complications, Prostate, Prostatectomy, Prostatic Neoplasms, Quality of Life, Radioisotope Teletherapy, Treatment Outcome, Practice Guidelines as Topic
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